Oxazinanes
Apexbio Technology LLC Tipiracil hydrochloride 183204-72-0 10mM (in 1mL H2O)
Tipiracil hydrochloride (CAS 183204-72-0) is a small-molecule inhibitor of thymidine phosphorylase (TP) an enzyme involved in the pyrimidine nucleoside salvage pathway By inhibiting TP tipiracil reduces the degradation of thymidine analogs thereby maintaining higher plasma concentrations of compounds such as trifluridine (FTD) when co-administered Tipiracil in combination with FTD constitutes the oral antitumor agent TAS-102 which is under clinical investigation In research settings tipiracil is used to enhance the pharmacological activity of nucleoside analogs by limiting their metabolic breakdown supporting studies on antitumor therapeutics and nucleotide metabolism
Apexbio Technology LLC Lofexidine (hydrochloride) 21498-08-8 10mM (in 1mL H2O)
Lofexidine hydrochloride (CAS 21498-08-8) is a selective 2-adrenergic receptor agonist demonstrating high affinity for the 2A-receptor subtype By activating presynaptic 2-adrenergic autoreceptors in the central nervous system lofexidine modulates noradrenergic neurotransmission which is implicated in opioid withdrawal physiology Following oral administration lofexidine is extensively absorbed with peak plasma concentrations achieved within approximately 3 hours Clinically it has been investigated for the management of opioid withdrawal symptoms with reported adverse effects including insomnia dry mucous membranes sedation dizziness and asthenia Lofexidine serves as a research tool in studies of adrenergic receptor pharmacology and opioid detoxification
Apexbio Technology LLC Tacrine hydrochloride 1684-40-8 10mM (in 1mL H2O)
Tacrine hydrochloride (CAS 1684-40-8) is a small molecule inhibitor of cholinesterases exhibiting potent inhibitory activity against both acetylcholinesterase (AChE IC 31 nM) and butyrylcholinesterase (BChE IC 25 6 nM) in vitro Additionally it has been shown to inhibit N-methyl-D-aspartate receptors (NMDARs) with an IC of approximately 26 M By modulating both cholinergic and glutamatergic signaling pathways tacrine hydrochloride is frequently employed in studies investigating the molecular mechanisms underlying Alzheimer s disease and exploring potential therapeutic strategies for neurodegenerative disorders
Selleck Chemical LLC Kevetrin hydrochloride
Kevetrin hydrochloride (Thioureidobutyronitrile) is a water-soluble small molecule and activator of the tumor suppressor protein p53 with potential antineoplastic activity
Selleck Chemical LLC Propacetamol hydrochloride S4867-1g
Propacetamol hydrochloride (PRO) is a water-soluble prodrug of paracetamol (PA) which can be parenterally administered as analgesic for the treatment of postoperative pain acute trauma and gastric and/or intestinal disorders
Selleck Chemical LLC Propacetamol hydrochloride S4867-25mg
Propacetamol hydrochloride (PRO) is a water-soluble prodrug of paracetamol (PA) which can be parenterally administered as analgesic for the treatment of postoperative pain acute trauma and gastric and/or intestinal disorders
Sigma Aldrich Fine Chemicals Biosciences Coniine hydrochloride phyp20MG
This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity water residual solvents inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH Co. KG
Sigma Aldrich Fine Chemicals Biosciences Europine hydrochloride phy10MG
This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity water residual solvents inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH Co. KG
Cayman Chemical O2545 hydrochloride
A potent water-soluble agonist of CB1 and CB2 receptors with Ki values of 1.5 and 0.32 nM, respectively; when dissolved in saline, is highly efficacious in mouse behavioral models when administered either intravenously or intracerebroventricularly
Cayman Chemical O2545 hydrochloride
A potent water-soluble agonist of CB1 and CB2 receptors with Ki values of 1.5 and 0.32 nM, respectively; when dissolved in saline, is highly efficacious in mouse behavioral models when administered either intravenously or intracerebroventricularly
Cayman Chemical O2545 hydrochloride
A potent water-soluble agonist of CB1 and CB2 receptors with Ki values of 1.5 and 0.32 nM, respectively; when dissolved in saline, is highly efficacious in mouse behavioral models when administered either intravenously or intracerebroventricularly
Cayman Chemical O2545 hydrochloride
A potent water-soluble agonist of CB1 and CB2 receptors with Ki values of 1.5 and 0.32 nM, respectively; when dissolved in saline, is highly efficacious in mouse behavioral models when administered either intravenously or intracerebroventricularly
AdipoGen Caroverine hydrochloride
Chemical. CAS 55750-05-5. Formula C22H27N3O2 . HCl . H2O. MW 401.93 . 18.0. Synthetic. Nonselective NMDA and AMPA glutamate receptor antagonist. A class B calcium-channel-blocker, antiglutamatergic agent and shown to act as an antioxidant.
AdipoGen Caroverine hydrochloride
Chemical. CAS 55750-05-5. Formula C22H27N3O2 . HCl . H2O. MW 401.93 . 18.0. Synthetic. Nonselective NMDA and AMPA glutamate receptor antagonist. A class B calcium-channel-blocker, antiglutamatergic agent and shown to act as an antioxidant.
Medchemexpress LLC HXR9 hydrochloride | 99.5% | 2754.67 | 1 MG
HXR9 hydrochloride is a cell-permeable peptide that acts as a competitive antagonist of HOX/PBX interaction. It selectively decreases cell proliferation and promotes apoptosis in cells with high HOXA/PBX3 gene expression, such as MLL-rearranged leukemic cells, by blocking the interaction between HOX and PBX transcription factors.
- Antagonizes the interaction between HOX and PBX transcription factors.
- Selectively decreases cell proliferation.
- Promotes apoptosis in cells with high HOXA/PBX3 gene expression.
- Appears as a white to off-white solid.
- Soluble in water (H2O) and PBS.
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