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Filtered Search Results
Medchemexpress LLC HY-18162 5mg Medchemexpress, JNJ-42153605 CAS:1254977-87-1 Purity:>98%
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Medchemexpress, HY-18162 5mg JNJ-42153605 CAS:1254977-87-1 JNJ-42153605 is a positive allosteric modulator of the metabotropic glutamate 2 (mGlu2) receptor with an EC50 of 17 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC AMG-548 dihydrochloride | 2518299-32-4 | 99.9% | 534.48 | 1 MG
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AMG-548 dihydrochloride | 2518299-32-4 | 99.9% | 534.48 | 1 MG
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eMolecules 170098-38-1 | Medchem Express | Alvimopan (dihydrate) | 5mg | 446271508 | HY-76657A | MFCD00927248 | 460.571 | C25H36N2O6
Ambeed | 1-Propyl-1234-tetrahydropyrimidine-24-dione | 100mg | 714081784 | A1127570 | 24466-52-2 | MFCD00466422 | 154.169 | C7H10N2O2
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![Medchemexpress LLC 3-(4-morpholinopyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl)phenol | 371935-74-9 | MFCD11983145 | 99.0% | 348.36 g/mol | C19H16N4O3 | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000213142.png-250.jpg)
Medchemexpress LLC 3-(4-morpholinopyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl)phenol | 371935-74-9 | MFCD11983145 | 99.0% | 348.36 g/mol | C19H16N4O3 | 50 MG
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A small-molecule research reagent that potently inhibits PI3K and mTOR signaling and is used in biochemical and cell-based studies. It also inhibits DNA-PK and has been reported to induce autophagy.
- Potent PI3K and mTOR inhibitor with reported low-nanomolar IC50s (p110α 8 nM; mTORC1 20 nM).
- Also inhibits DNA-PK (IC50 2 nM).
- Used for biochemical and cell-based research; for research use only.
- Stable as a powder at -20°C (up to 3 years) or 4°C (up to 2 years).
- Recommended in-solution storage: -80°C (1 year) or -20°C (6 months).
- Supplied in milligram-scale quantities suitable for analytical and cellular studies.
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Apexbio Technology LLC PI-1840 1401223-22-0 50mg
PI-1840 (CAS 1401223-22-0) is a potent selective and rapidly reversible noncovalent inhibitor of the proteasome chymotrypsin-like (CT-L) activity It exhibits an IC50 of 27 nM against CT-L catalytic function of the proteasome with significantly greater selectivity over other proteolytic activities including PGPH-L and T-L In MDA-MB-468 human breast cancer cells PI-1840 inhibits CT-L activity (IC50 0 37 M) suppresses cell viability and proliferation and induces accumulation of CT-L substrates such as I B- p27 and Bax ultimately triggering apoptosis via PARP cleavage and caspase-3 activation In vivo PI-1840 markedly reduces tumor growth in a breast cancer xenograft model This compound is valuable for investigating proteasome function apoptosis and cancer biology
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Medchemexpress LLC HY-100748 5mg Medchemexpress, CXD101 CAS:934828-12-3 Purity:>98%
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Medchemexpress, HY-100748 5mg CXD101 CAS:934828-12-3 CXD101 is a class I-selective HDAC inhibitor (HDAC1 ( IC 50 , 63 nM), HDAC2 ( IC 50 , 570 nM), HDAC3 ( IC 50 , 550 nM). CXD101 has no activity against HDAC class II [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Matrix Scientific PAROXETINE HYDROCHLORIDE HE-1G
Paroxetine hydrochloride hemihydrate, >95%; 1g,C38H42F2N2O7, MFCD03658863, mw 676.76, [110429-35-1]
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Medchemexpress LLC GPR40/FFAR1 modulator 1 | 874755-26-7 | 98.28% | 389.41 | 50 MG
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GPR40/FFAR1 modulator 1 acts as an agonist and an allosteric modulator for Gq-coupled free fatty acid receptor 1 (GPR40/FFAR1). This product is intended for research use only.
- Agonist and allosteric modulator for Gq-coupled free fatty acid receptor 1.
- Purity of 98.28%.
- Solid appearance.
- Off-white to light yellow color.
- Soluble in DMSO (31.25 mg/mL).
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Apexbio Technology LLC PI-3065 955977-50-1 50mg
PI-3065 (CAS 955977-50-1) is a selective small-molecule inhibitor targeting the phosphoinositide 3-kinase delta (PI3K ) isoform It exhibits potent inhibitory activity with reported Ki and IC50 values of approximately 1 5 nM and 5 nM respectively PI-3065 demonstrates marked selectivity showing significantly lower inhibitory potency against the related isoforms PI3K PI3K and PI3K In preclinical models treatment with PI-3065 suppressed growth and metastasis of 4T1 tumors extended survival and reduced tumor-related pathological outcomes This compound serves as a valuable tool for studying PI3K -driven signaling pathways in oncology and immunology research contexts
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eMolecules 3466-80-6 | 2-Phenylpiperidine | Apollo Scientific | MFCD00270125 | 161.248 | C11H15N | 95.000 | C1CCC(NC1)c1ccccc1 | 1g | 562444498
2-Phenylpiperidine | Apollo Scientific | 3466-80-6 | MFCD00270125 | 161.248 | C11H15N | 95.000 | C1CCC(NC1)c1ccccc1 | 1g | 562444498
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eMolecules 182618-86-6 | 1-BOC-4-(4-nitrophenyl)piperazine | MFCD02187326 | 1g
Ambeed | N-(45-Dihydrothiazol-2-yl)-4-(4455-tetramethyl-132-dioxaborolan-2-yl)benzamide | 100mg | 714084042 | A1537616 | 2828439-73-0 | 332.230 | C16H21BN2O3S
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Accela Chembio Inc (3s | 4r)-4-(4-fluorophenyl)-1-methyl-3-piperidinemethanol | 25g | 105812-81-5 | MFCD06658161 | 97+% | Shelf Life: 1260 Days | Light Sensitive/moisture Sensitive/+4
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(3s | 4r)-4-(4-fluorophenyl)-1-methyl-3-piperidinemethanol | 25g | 105812-81-5 | MFCD06658161 | 97+% | Shelf Life: 1260 Days | Light Sensitive/moisture Sensitive/+4
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Medchemexpress LLC Casopitant mesylate | 414910-30-8 | 99.8% | C31H39F7N4O5S | 10MG
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Casopitant mesylate is a potent, selective, brain-permeable, and orally active neurokinin-1 (NK1) receptor antagonist supplied as the mesylate salt for preclinical research into antiemetic mechanisms, including chemotherapy-induced and postoperative nausea and vomiting. The compound is offered with high reported purity and in multiple formats for laboratory use.
- Potent, selective NK1 receptor antagonist
- Brain permeable and orally active
- Supplied as mesylate salt for improved handling
- High reported purity suitable for research
- Available in multiple sizes and solution formats
- Intended for preclinical antiemetic and pharmacology studies
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eMolecules 3466-80-6 | 2-Phenylpiperidine | ChemScene | MFCD00270125 | 161.248 | C11H15N | 97.000 | C1CCC(NC1)c1ccccc1 | 1g | 536778997
2-Phenylpiperidine | ChemScene | 3466-80-6 | MFCD00270125 | 161.248 | C11H15N | 97.000 | C1CCC(NC1)c1ccccc1 | 1g | 536778997
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eMolecules 2079886-19-2 | Medchem Express | GSK4028 | 5mg | 437898925 | HY-101027A | 377.286 | C17H21BrN4O
Ambeed | 35-Bis(trifluoromethyl)benzenesulfonamide | 1g | 516644791 | A102533 | 39213-22-4 | MFCD01935138 | 293.180 | C8H5F6NO2S
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