Pyrazines
TARGETMOL CHEMICALS INC IOX4 25MG
Also available in 2 mg 5 mg 10 mg 50 mg 100 mg 200 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. IOX4 is a potent PHD2 inhibitor (IC50 = 1.6 nM)purity: 98%
TARGETMOL CHEMICALS INC PKCIOTA-IN-2 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. PKCiota-IN-2 (PKCiota-IN-49) is a selective and potent PKCiota (PKC-(iota)) inhibitor with an IC50 of 2.8 nM. PKCiota-IN-2 also inhibits PKC-(alpha) and PKC-(epsilon) with IC50s of 71 nM and 350 nM respectivelypurity: 99%
TARGETMOL CHEMICALS INC NAE-IN-M22 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. NAE-IN-M22 (NEDD8 inhibitor M22) is a selective potent and reversible inhibitor of NEDD8 activating enzyme (NAE). NAE-IN-M22 inhibits multiple cancer cell lines and induces apoptosis in A549 cells. NAE-IN-M22 also can inhibit tumor growth in vivo. purity: 98%
TARGETMOL CHEMICALS INC AMI-1 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. AMI-1 is an effective and selective Histone Methyltransferase (HMT) inhibitor (IC50 3.0/8.8 uM for yeast Hmt1p and human PRMT1). purity: 99%
TARGETMOL CHEMICALS INC AS1949490 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. AS1949490 activated glucose metabolism via up-regulation of GLUT1 gene in L6 myotubes[1][2]. AS1949490 is a potent and selective SHIP-2 (SH2 domain-containing inositol 5′ phosphatase 2) inhibitor with an IC50 of 620 nM. purity: 99%
TARGETMOL CHEMICALS INC IXAZOMIB 10MG
Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Ixazomib (MLN2238) a second generation boron-containing peptide proteasome inhibitor (PI) inhibits the chymotrypsin-like proteolytic ((beta)5) site of the 20S proteasome (IC50/Ki 3.4/0.93 nM in cell-free assays) also inhibits the caspase-like ((beta)1) and trypsin-like ((beta)2) proteolytic sites (IC50 31/3500 nM). purity: 98%
TARGETMOL CHEMICALS INC PARP10-IN-2 5MG
Also available in 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. PARP10-IN-2 is a potent inhibitor of PARP10 a mono-ADP-ribosyltransferase with an IC50 value of 3.64 uM for human PARP10.PARP10-IN-2 also inhibited PARP2 and PARP15 with IC50 values of 27 uM and 11 uM respectively. purity: 99%
TARGETMOL CHEMICALS INC ISRIB-A15 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. ISRIB-A15 (ISR-IN-2) is an potent inhibitor of the integrated stress response with an EC50 of 0.8 nM. purity: 98%
eMolecules 475576-83-1 | 2,7,8-TRIAMINO-4-(3-BROMO-4,5-DIMETHOXYPHENYL)-4H-CHROMENE-3-CARBONITRILE | Broadpharm | MFCD24038951 | 417.263 | C18H17BrN4O3 | 98.000 | COc1cc(cc(Br)c1OC)C1C(C#N)=C(N)Oc2c(N)c(N)ccc12 | 1g | 249969204
2,7,8-TRIAMINO-4-(3-BROMO-4,5-DIMETHOXYPHENYL)-4H-CHROMENE-3-CARBONITRILE | Broadpharm | 475576-83-1 | MFCD24038951 | 417.263 | C18H17BrN4O3 | 98.000 | COc1cc(cc(Br)c1OC)C1C(C#N)=C(N)Oc2c(N)c(N)ccc12 | 1g | 249969204
TARGETMOL CHEMICALS INC CAMKP INHIBITOR 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. CaMKP Inhibitor can inhibit CaMKP. purity: 99%
TARGETMOL CHEMICALS INC PROTOHYPERICIN 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. Protohypericin is a naturally occurring naphthodianthrone derived from plant Hypericum perforatum.Radioiodinated protohypericin is used in Tumor necrosis targeted radiotherapy. Protohypericin exhibits photocytotoxicity. purity: 98%
eMolecules 54013-04-6 | Ethyl 5-chloropyrazine-2-carboxylate | MFCD18070850 | 1g
Ambeed | Ethyl 5-chloropyrazine-2-carboxylate | 1g | 598443289 | A162332 | 54013-04-6 | MFCD18070850 | 186.600 | C7H7ClN2O2
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