Pyrazines
TARGETMOL CHEMICALS INC ML400 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. ML400 (CID73050863) is an allosteric inhibitor of LMPTP with an EC50 of 1uM. ML400 displays good cell-based activity and rodent pharmacokinetics. purity: 99%
TARGETMOL CHEMICALS INC LP-471756 5MG
Also available in 10 mg 25 mg 50 mg 100 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. LP-471756 is a specific antagonist of GPR139 and inhibits LP-360924-stimulated cAMP production (IC50 = 640 nM). purity: 99%
TARGETMOL CHEMICALS INC ILOMASTAT 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Ilomastat (GM6001) (GM6001 Galardin) is a broad spectrum matrix metalloprotease (MMP) inhibitor. purity: 99%
TARGETMOL CHEMICALS INC CCX140 25MG
Also available in 2 mg 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. CCX140 (CCX140-B) (CCX140-B) is an antagonist of CCR2. purity: 99%
TARGETMOL CHEMICALS INC PDE4B-IN-2 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. PDE4B-IN-2 (A 33) is an orally active and selective PDE4B inhibitor with an IC50 of 15 nM. PDE4B-IN-2 inhibits PDE4D (IC50=1.7 µM). PDE4B-IN-2 exhibits potent anti-inflammatory effects. purity: 99%
TARGETMOL CHEMICALS INC SR9009 25MG
Also available in 1 mg 2 mg 5 mg 10 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. SR9009 (Stenabolic) a REV-ERB agonist increases the constitutive repression of genes regulated by REV-ERB(alpha)/ERB(beta) (IC50 670/800 nM). Through activation of REV-ERB SR9009 can decrease circadian locomotor activity during the dark phase and alter the expression pattern of core clock genes in the hypothalami of mice. The circadian pattern of expression of an array of metabolic genes in the liver skeletal muscle and adipose tissue was also altered in mice exposed to SR9009 resulting in increased energy expenditure. In Diet-induced obese mice SR9009 (100 mg/kg i.p. b.i.d. for 30 days) could decrease fat mass and markedly improve dyslipidemia and hyperglycemia. purity: 99%
TARGETMOL CHEMICALS INC AZ PFKFB3 26 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. AZ PFKFB3 26 is an effective and selective PFKFB3 inhibitor with an IC50 of 23 nM. The IC50s for PFKFB1 and PFKFB2 are 2.06 and 0.384 uM respectively. purity: 98%
eMolecules 632-46-2 | 2,6-Dimethylbenzoic acid | Ambeed | MFCD00002483 | 150.177 | C9H10O2 | 98.000 | Cc1cccc(C)c1C(O)=O | 1g | 490514783
2,6-Dimethylbenzoic acid | Ambeed | 632-46-2 | MFCD00002483 | 150.177 | C9H10O2 | 98.000 | Cc1cccc(C)c1C(O)=O | 1g | 490514783
TARGETMOL CHEMICALS INC PRANIDIPINE 10MG
Also available in 1 mg 5 mg 25 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Pranidipine (OPC-13340) is a novel long-acting 14-dihydropyridine calcium channel blocker. It prolongs acetylcholine-induced relaxation in presence of endothelium as well as nitroglycerin-induced relaxation in absence of endothelium. It also has antihypertensive activity. purity: 99%
TARGETMOL CHEMICALS INC AHN 1-055 HYDROCHLORIDE 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. AHN 1-055 hydrochloride (3(alpha)-Bis-(4-fluorophenyl) Methoxytropane hydrochloride) is an inhibitor of dopamine transporter (DAT) and dopamine uptake(IC50 = 71 nM). purity: 99%
TARGETMOL CHEMICALS INC TELOTRISTAT ETIPRATE 25MG
Also available in 2 mg 5 mg 10 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Telotristat Etiprate (LX 1606 Hippurate) is an orally bioavailable tryptophan hydroxylase (TPH) inhibitor with potential antiserotonergic activity. purity: 99%
TARGETMOL CHEMICALS INC PBRM1-BD2-IN-5 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. PBRM1-BD2-IN-5 is a potent PBRM1 Bromodomain inhibitor with Kd values of 1.5 uM and 3.9 uM for PBRM1-BD2 and PBRM1-BD5 respectively and an IC50 value of 0.26 uM for PBRM1-BD2. PBRM1-BD2-IN-5 reduces the binding of full-length PBRM1 within the PBAF complex in cell lysates to acetylated histone peptide. PBRM1-BD2-IN-5 can be used to research anticancer. purity: 99%
TARGETMOL CHEMICALS INC SKF83959 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. SKF83959 a benzazepine analog is a selective and potent partial agonist of the dopamine D1 receptor with Ki values of 1.18 7.56 920 and 399 nM for rat D1 D5 D2 and D3 receptors respectively.SKF83959 is a potent variant modulator of the sigma ((sigma))-1 receptor which ameliorates cognitive dysfunction for the study depression and Alzheimer's disease. purity: 98%