Pyrazines
TARGETMOL CHEMICALS INC CEFTAROLINE FOSAMIL 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Ceftaroline fosamil (TAK-599) is a cephalosporin with activity against Gram-positive pathogens. purity: 98%
TARGETMOL CHEMICALS INC CCT245737 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. CCT245737 (SRA737) is an orally active and selective Chk1 inhibitor (IC50 1.3 nM); CCT245737 shows much less activity against Chk2 (IC50 2440 nM). purity: 99%
TARGETMOL CHEMICALS INC VESNARINONE 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. Vesnarinone (Arkin) (INN) is a mixed phosphodiesterase 3 inhibitor and ion-channel modifier that has modest dose-dependent positive inotropic activity but minimal negative chronotropic activity. It also suppresses cell proliferation and induces apoptosis by inducing the expression of p21 an inhibitor of cyclin-dependent kinase activity in p53-mediated cell cycle arrest. purity: 98%
TARGETMOL CHEMICALS INC CYANIDIN CHLORIDE 10MG
Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Cyanidin Chloride the main phenolic antioxidant in the grape (Vitis vinifera) in particular in the liposomal forms could be used for treatment of diabetes mellitus complications. purity: 98%
TARGETMOL CHEMICALS INC FONDAPARINUX SODIUM 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. Fondaparinux sodium (SR-90107A) is an antithrombin-dependent factor Xa inhibitor with antithrombotic activity. purity: 98%
TARGETMOL CHEMICALS INC 1400W DIHYDROCHLORIDE 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. 1400W dihydrochloride (N-(3-(Aminomethyl)benzyl)acetamidine) is a highly effective and specific inhibitor of inducible NOS2 (iNOS). purity: 99%
TARGETMOL CHEMICALS INC SB-505124 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. SB505124 is a selective inhibitor of TGF(beta)R for ALK4 ALK5. purity: 99%
TARGETMOL CHEMICALS INC RANOLAZINE 200MG
Also available in 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Ranolazine (RS 43285-003) is a calcium uptake inhibitor via the sodium/calcium channel used to treat chronic angina. It affects the sodium-dependent calcium channels during myocardial ischemia in rabbits by altering the intracellular sodium level. purity: 98%
TARGETMOL CHEMICALS INC DAPANSUTRILE 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 200 mg 500 mg 1000 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Dapansutrile is a potent selective and orally active NLRP3 inflammasome inhibitor with Anti-inflammatory and analgesic activity. purity: 98%
TARGETMOL CHEMICALS INC TALMAPIMOD 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Talmapimod (SCIO-469) is an selective orally active and ATP-competitive p38(alpha) inhibitor with IC50 of 9 nM and 90 nM for p38(alpha) and p38(beta) respectively. Talmapimod exhibits at least 2000-fold selectivity over a panel of 20 kinases including other MAPKs. purity: 100%
TARGETMOL CHEMICALS INC IXAZOMIB 10MG
Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Ixazomib (MLN2238) a second generation boron-containing peptide proteasome inhibitor (PI) inhibits the chymotrypsin-like proteolytic ((beta)5) site of the 20S proteasome (IC50/Ki 3.4/0.93 nM in cell-free assays) also inhibits the caspase-like ((beta)1) and trypsin-like ((beta)2) proteolytic sites (IC50 31/3500 nM). purity: 98%
TARGETMOL CHEMICALS INC CAY10434 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. CAY10434 is an active inhibitor of CYP4A hydroxylase with an IC50 value of 8.8 nM in human kidney microsomal test. The maximum contractile value (Emax) of CAY 10434 was 6764 mg in improving the contractile process of angiotensin II. purity: 99%
Cell Signaling Technology Phospho-Akt2 Ser474 Matched
Phospho-Akt2 (Ser474) Matched Antibody Pair 1 Kit
TARGETMOL CHEMICALS INC MICLXIN 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. Miclxin (DS37262926) is a novel MIC60 inhibitor that induces apoptosis through mitochondrial stress in mutant tumor cells via (beta)-catenin.Miclxin is a potent inhibitor of mutant (beta)-catenin which is involved in the Wnt signaling pathway.Miclxin induces (beta)-catenin-dependent apoptosis leading to mitochondrial damage and loss of mitochondrial membrane. Miclxin has anti-tumor activity and kills tumors by targeting MIC60. purity: 99%
TARGETMOL CHEMICALS INC CARBOXYATRACTYLOSIDE 25MG
Also available in 5 mg 10 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Carboxyatractyloside (Carboxyatractyloside tripotassium salt) is a natural product. It acts as an inhibitor of ADP/ATP carrier inhibits mitochondrial ADP/ATP transport. purity: 99%