Pyridines and derivatives
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- (245)
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- (2)
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- (1)
- (1)
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- (1)
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- (1)
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- (4)
- (8)
- (7)
- (12)
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- (875)
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- (357)
- (2)
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- (2)
- (1)
- (1)
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- (1)
- (1,713)
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- (1)
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- (128)
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- (1)
- (1)
- (63)
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- (1)
- (1)
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- (1)
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- (1)
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- (1)
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- (2)
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- (6)
- (7)
- (12)
- (1)
- (1)
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- (1)
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- (11)
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- (2)
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- (1)
- (1)
- (2)
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- (3)
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- (1)
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- (1)
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Filtered Search Results
Apexbio Technology LLC APEXBIO TECHNOLOGY LLC
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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5000570771 NOTOPTEROL-20MG
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Fc-11 (PROTAC FAK degrader) | 2271035-37-9 | ≥98.0% | 949.92 g/mol | C41H42F3N13O9S | 5 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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FC-11 is a PROTAC (proteolysis-targeting chimera) that induces targeted degradation of focal adhesion kinase (FAK). It links a CRBN-recruiting pomalidomide moiety to a FAK-binding ligand via a chemical linker to achieve potent cellular degradation (reported DC90 ≈ 1 nM), and is intended for biochemical and cellular studies of FAK biology.
- Potent FAK degradation with DC90 ≈ 1 nM.
- CRBN-mediated mode of action via pomalidomide ligand.
- High purity suitable for biological assays (≥98.0%).
- Molecular weight 949.92 g/mol and formula C41H42F3N13O9S.
- Supplied in small research quantities, for example 5 MG packs.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Apexbio Technology LLC APEXBIO TECHNOLOGY LLC
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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5000570808 PRIMARY-ANTIBODIES
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Medchemexpress LLC Interferon alpha 1, mouse (P. pastoris, His-tagged) | 10 UG
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Recombinant mouse interferon alpha 1 (IFN-α1) expressed in Pichia pastoris with a C-terminal His tag. This type I interferon has antiviral and immunomodulatory activity and is provided as a purified recombinant protein for research use in signaling studies, antiviral assays, and immune response experiments.
- Mouse interferon alpha 1 suitable for research applications.
- Expressed in P. pastoris to support eukaryotic protein processing.
- C-terminal His tag enables affinity purification and detection.
- Functional in antiviral and immunomodulatory assays.
- Provided in a research-scale quantity for biochemical and cell-based assays.
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Medchemexpress LLC 2-(4-(2,3,4-trimethoxybenzyl)piperazin-1-yl)ethyl nicotinate | 2254741-41-6 | 99.1% | 415.48 g·mol⁻¹ | C22H29N3O5 | 5 MG
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Ninerafaxstat is an orally active cardiac mitotrope used for research on cardiac energetics. It partially inhibits fatty acid oxidation by targeting 3-ketoacyl-CoA thiolase, shifting myocardial substrate utilization toward glucose oxidation and improving cardiac energy efficiency. Supplied as a high-purity research compound with documented molecular properties and formulation for laboratory use.
- Partial fatty acid oxidation inhibition improves energy efficiency.
- Oral bioactivity supports in vivo research models.
- High reported purity suitable for experimental use.
- Documented molecular weight and formula for analytical characterization.
- Applicable to studies of cardiac metabolism and disease models.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000296721 5-IAF 10MG
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Medchemexpress LLC GSK591 (EPZ015866) | 1616391-87-7 | ≥95.0% | 380.48 g/mol | C22H28N4O2 | 1 MG
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GSK591 (EPZ015866) is a selective small-molecule inhibitor of protein arginine methyltransferase 5 (PRMT5) used as a research chemical probe. It shows low-nanomolar potency in biochemical assays and modulates PRMT5-mediated arginine methylation in cellular models, supporting mechanistic studies of epigenetic regulation and PRMT5-dependent signaling. For research use only.
- Potent PRMT5 inhibition at low-nanomolar concentrations.
- High selectivity for PRMT5 versus related methyltransferases.
- Cell-active modulation of arginine methylation in vitro.
- Well-characterized for mechanistic and target validation studies.
- Available in both free base and hydrochloride salt forms for formulation flexibility.
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Medchemexpress LLC (R,S)-anatabine | 2743-90-0 | MFCD00078278 | 99.7% | 160.22 | C10H12N2 | 5MG
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(R,S)-Anatabine is an analytical reference standard of the tobacco alkaloid anatabine provided as a solid for use in research and analytical workflows. It is intended for chromatographic calibration, method development, and biochemical assay verification where a defined reference compound is required.
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Medchemexpress LLC AChE/BChE-IN-10 | 2924824-48-4 | C26H30N2O2 | 25 MG
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AChE/BChE-IN-10 is a potent dual inhibitor of Acetylcholinesterase (AChE) and Butyrylcholinesterase (BChE), exhibiting good blood-brain barrier permeability. This compound is capable of inhibiting Aβ-aggregation and is utilized in Alzheimer's disease (AD) research.
- Potent dual AChE and BChE inhibitor
- Exhibits good blood-brain barrier permeability
- Can inhibit Aβ-aggregation
- Used in Alzheimer's disease (AD) research
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Medchemexpress LLC Methanone, [2-fluoro-4-[2-(4-methoxyphenyl)ethynyl]phenyl][(3R)-3-hydroxy-1-piperidinyl] | 1443118-44-2 | 99.1% | 353.39 | 25 MG
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ML337 is a selective and brain-penetrant negative allosteric modulator of mGlu3, with an IC50 of 593 nM. It possesses a favorable dystrophia myotonica protein kinase (DMPK) and ancillary pharmacology profile. ML337 is also a click chemistry reagent, containing an Alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- Selectivity: highly selective for mGlu3, with no activity at mGlu1, 2, 4, 5, 6, 7, and 8 at concentrations up to 30 μM.
- Brain-penetrant: capable of crossing the blood-brain barrier.
- Dmpk profile: possesses a favorable dystrophia myotonica protein kinase (DMPK) profile.
- Click chemistry reagent: contains an Alkyne group, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules.
- Appearance: off-white to light yellow solid.
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Medchemexpress LLC N-pivaloylglycine | 23891-96-5 | MFCD06385042 | ≥98.0% | 159.18 g/mol | C7H13NO3 | 1 G
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N-Pivaloylglycine is an amino acid derivative of glycine supplied for laboratory research use. It is provided as a solid reagent for in vitro and analytical applications and is not intended for human or clinical use. Small package sizes suit synthetic chemistry, analytical standards, and other bench-scale workflows.
- Glycine derivative suitable for research and analytical use.
- Solid form, easy to handle and store.
- High purity for reliable experimental results.
- Useful as a synthetic intermediate or analytical standard.
- Available in small laboratory package sizes for convenience.
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Medchemexpress LLC Exendin (5-39) | 196109-27-0 | 99.4% | 3806.30 | 1 MG
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Exendin (5-39) is a potent antagonist of the glucagon-like peptide 1 (GLP-1) receptor. It has been shown to improve memory impairment in rats treated with β-amyloid protein.
- Potent glucagon-like peptide 1 (GLP-1) receptor antagonist.
- Improves memory impairment in β-amyloid protein-treated rats.
- Increases GLT-1 protein levels in the hippocampus of male Wistar rats (in vivo study).
- Decreases fEPSP decay time and increases the input-output relation in the dentate gyrus (in vivo study).
- Inhibits long-term depression in the dentate gyrus (in vivo study).
- Available in various quantities: 1 mg, 5 mg, 10 mg, 50 mg, 100 mg.
- Purity of 99.43%.
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Medchemexpress LLC CD117/c-Kit Mouse 50ug
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CD117/c-Kit protein is a tyrosine protein kinase that acts as a cell surface receptor for KITLG/SCF and regulates cell survival proliferation hematopoiesis stem cell maintenance gametogenesis mast cell development migration function and melanogenesis CD117/c-Kit Protein Mouse (HEK293 His) is the recombinant mouse-derived CD117/c-Kit protein expressed by HEK293 with C-10 His labeled tag
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Medchemexpress LLC Ml311 | 315698-17-0 | 99.0% | 415.45 | C23H24F3N3O | 1 MG
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ML311 is a small-molecule research compound that selectively inhibits the Mcl-1/Bim protein-protein interaction and is used in cellular and in vivo pharmacology studies. Reported data show submicromolar cellular potency across multiple cancer cell lines. The product is supplied as a high-purity solid with validated solubility and storage recommendations for preclinical use.
- Potent and selective inhibitor of the Mcl-1/Bim interaction.
- High purity (approximately 99%).
- White to off-white solid suitable for analytical and biological assays.
- DMSO soluble with published in vitro and in vivo formulation protocols.
- Reported submicromolar EC50/GI50 activity across multiple cell lines.
- Packaged in multiple milligram quantities for preclinical studies.
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Medchemexpress LLC Ranibizumab anti-VE 25mg | 25mg
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Ranibizumab (RG-6321) (anti-VEGF) is a humanized anti-VEGF monoclonal antibody fragment and can recognize all VEGF-A isoforms (VEGF110 VEGF121 and VEGF165)[1] Ranibizumab (anti-VEGF) slows vision loss in vivo and is used for wet age-related macular degeneration (AMD) research[1]
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