Pyridines and derivatives

Aromatic organic compounds consist of an aromatic six-membered ring containing one nitrogen atom and five carbon atoms; includes compounds derived from pyridines.

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6,256 – 6,270 of 178,220 results

6,256

Cayman Chemical PDM 11 Fatty Acids and Derivat

A derivative of resveratrol; inactive in vitro in assays of resveratrol activity; does not affect proliferation of K562, HT-29, and HepG2 cells

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6,257

Apexbio Technology LLC PD-1/PD-L1 inhibitor 1(Synonyms: BMS-202, PD-1/PD-L1 interaction inhibitor 1, PD-L1 inhibitor BMS-202, BMS202), 25mg, CAS: 1675201-83-8.

PD-1/PD-L1 inhibitor 1 (CAS 1675201-83-8) is a small molecule inhibitor targeting the interaction between programmed cell death protein 1 (PD-1) and its ligand PD-L1 By disrupting PD-1/PD-L1 signaling this agent restores and enhances T-cell activation demonstrating immunomodulatory properties In vitro assays (HTRF binding assay) report IC50 values ranging from 6 to 100 nM Current preclinical evidence positions PD-1/PD-L1 inhibitor 1 as a candidate compound for studying tumor immunity and infectious diseases such as hepatitis C virus infection

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6,258

Medchemexpress LLC Ficerafusp alfa 1mg | 1mg

HY-P990957 is an EGFR-targeting IgG1 type chimeric antibody the recommed isotype control is Human IgG1 kappa Isotype Control (HY-P99001)[1]

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6,259

Medchemexpress LLC Efizonerimod alfa 5mg | 5mg

Efizonerimod alfa is a potent monoclonal antibody OX40 activator Efizonerimod alfa can be used for cancer research[1]

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6,260

Medchemexpress LLC Lucifer yellow CH (dipotassium salt) | 71206-95-6 | MFCD00013445 | 99.8% | 521.57 | C13H9K2N5O9S2 | 50 MG

Lucifer Yellow CH (dipotassium salt) is a high-intensity fluorescent probe containing free hydrazyl groups. It is used as a biological tracer for monitoring neuronal branching and regeneration, detecting and characterizing gap junctions, and performing selective cell ablation after aldehyde fixation. The dye has an approximate excitation/emission of 430 nm/540 nm and is supplied as a solid for preparation of stock solutions.

High fluorescence intensity for sensitive detection.
Suitable for neuronal tracing and regeneration studies.
Enables gap junction detection and characterization.
Reacts with fatty aldehydes, allowing post-fixation labeling.
Supplied as a solid and available as a DMSO solution for convenience.
Stock solutions should be stored protected from light and avoid repeated freeze-thaw cycles.

Pricing & Availability

6,261

Medchemexpress LLC Phytohemagglutinin P | 9008-97-3 | MFCD00165279 | 5 MG

Phytohemagglutinin P (PHA-P) is a mitogen that selectively stimulates cells of hematogenous or lymphoid monocytic origin. It is intended for research use only, supporting studies on cellular responses and proliferation.

Selectively stimulates cells of hematogenous or lymphoid monocytic origin
Stimulates decidual CD8+ T lymphocytes to produce interferon gamma and interleukin 8
Appears as a white to light yellow solid
Derived from plants (Leguminosae, Glycine max (L.) merr)

Pricing & Availability

6,262

Medchemexpress LLC Molidustat | 1154028-82-6 | 99.7% | 1 ML

Molidustat (BAY 85-3934) is an orally active inhibitor of hypoxia-inducible factor prolyl hydroxylase (HIF-PH) that elevates circulating erythropoietin (EPO) levels. It is used in research for renal anemia, stabilizing hypoxia-inducible factor and increasing erythropoietin in vivo. With IC50 values of 480 nM for PHD1, 280 nM for PHD2, and 450 nM for PHD3, it can induce detectable levels of HIF-1α in HeLa cells.

Orally active HIF-PH inhibitor
Elevates circulating erythropoietin (EPO) levels
Used in research for renal anemia
Induces detectable levels of HIF-1α in HeLa cells
Stabilizes hypoxia-inducible factor (HIF) in vivo

Pricing & Availability

6,263

Medchemexpress LLC CUTC protein, human (His-tag) | >95.0% | 500 UG

Recombinant full-length human CUTC protein, expressed in Escherichia coli with an N-terminal 6xHis tag, supplied as a purified protein for research use. The protein corresponds to UniProt accession Q9NTM9 (M1-V273) and is intended for biochemical and metal-binding studies; refer to the certificate of analysis for batch-specific quality details.

Purity greater than 95% by reducing SDS-PAGE.
Endotoxin level below 1 EU/μg (LAL tested).
Full-length sequence corresponding to UniProt Q9NTM9 (M1-V273).
Approximate molecular weight ~32 kDa.
Expressed in Escherichia coli and carrying an N-terminal 6xHis tag.
Storage: store at -20°C; aliquot and avoid repeated freeze-thaw; long-term at -80°C.
Provided as a 500 μg package.

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6,264

Medchemexpress LLC 5-PAHSA 100mg | 1481636-41-2 | 538.89 g/mol | C34H66O4 | 100 MG

5-PAHSA (5-(palmitoyloxy)octadecanoic acid) is a fatty-acid-derived signaling lipid (a FAHFA) used as a research reagent and analytical standard for studies of lipid signaling, metabolism, inflammation, and insulin sensitivity. Molecular formula C34H66O4; molecular weight 538.89 g/mol. Intended for research use only.

Endogenous fatty acid ester of hydroxy fatty acid (FAHFA).
Reported anti-inflammatory and insulin-sensitizing activity in animal models.
Suitable as an analytical reference standard for LC-MS and biochemical assays.
Available as a solid in multiple pack sizes, including 100 mg.
Commonly used in metabolic and lipid signaling research workflows.

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6,265

Sigma Aldrich Fine Chemicals Biosciences Sodum thocyanate soluto500ML

SODIUM Sodum thocyanate soluto500ML

Pricing & Availability

6,266

Medchemexpress LLC Methyl 6-amino-6-deoxy-2,3-di-O-tetradecyl-alpha-D-glucopyranoside | 1115270-63-7 | MFCD31813901 | 98.0% | 585.94 g/mol | C35H71NO5 | 25MG

IAXO-102 is a small-molecule TLR4 antagonist supplied for research use that inhibits TLR4-mediated signaling, reducing MAPK and NF-κB (p65) phosphorylation and downstream inflammatory protein expression in vitro and in vivo.

High purity (98.0%) suitable for research applications.
Off-white solid with molecular formula C35H71NO5 and molecular weight 585.94 g/mol.
Soluble in ethanol and DMSO; ethanol 50 mg/mL and DMSO 3.33 mg/mL (may require ultrasonic or warming).
Provides example in vivo vehicle formulations that achieve clear solutions at ≥0.83 mg/mL.
Recommended storage: powder at -20°C (3 years) or 4°C (2 years); in solvent at -80°C (2 years).
Suitable for pharmacology and immunology studies of TLR4 signaling and inflammation models.

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6,267

Apexbio Technology LLC MHC class II antigen (45-57) [Homo sapiens] 25mg

MHC class II antigen 45-57 is a synthetic peptide derived from human major histocompatibility complex class II molecules It is designed to facilitate studies on antigen presentation by MHC class II molecules which bind extracellularly derived peptide antigens and present them to CD4 helper T lymphocytes thereby initiating adaptive immune responses MHC class II antigen 45-57 exerts its biological activity primarily by serving as a model antigenic peptide for investigating MHC II-mediated antigen presentation and T-cell activation Based on these properties MHC class II antigen 45-57 holds research potential in studies of MHC II-mediated immune responses T-cell activation and the cellular immune mechanisms involved in pathogen defense and autoimmune diseases

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6,268

Medchemexpress LLC Lactonic sophorolipid | 148409-20-5 | 97.3% | 688.80 | 25 MG

Lactonic sophorolipid acts as an apoptosis inducer and antimicrobial surfactant with antitumor activity. It regulates Bax/Bcl-gene expression via caspase-3/9, promoting apoptosis in tumor cells. It also disrupts cell membrane permeability for antibacterial effects (MIC 100-400 μg/mL for oral pathogens) and promotes mitochondrial membrane potential depolarization, activating the intrinsic apoptotic pathway. It can synergize with antibiotics and is used in liver cancer research and oral hygiene antibacterial agent development.

Induces apoptosis in tumor cells
Regulates Bax/Bcl-gene expression
Disrupts cell membrane permeability
Exerts antibacterial effects
Promotes mitochondrial membrane potential depolarization
Activates the intrinsic apoptotic pathway
Synergizes with antibiotics
Inhibits HepG2 cell viability
Inhibits proliferation in colon cancer cells
Disrupts biofilm formation

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6,269

Sigma Aldrich Fine Chemicals Biosciences Lactoferrin human mil100MG

Lactoferrin human mil100MG

Pricing & Availability

6,270

Medchemexpress LLC 17α-Hydroxyprogesterone (standard) | 68-96-2 | 99.8% | 50 MG

17α-Hydroxyprogesterone (Standard) is the analytical standard of 17α-Hydroxyprogesterone. This product is intended for research and analytical applications. It is commonly used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.

Application: Used as a reference standard in assays for qualitative, quantitative, and methodological research experiments, particularly in techniques like HPLC, GC, and MS.
Molecular weight: 330.47
Formula: C₂₁H₃₀O₃
Appearance: Solid, white to off-white.
Structure classification: Steroids.
Initial source: Endogenous metabolite; disease markers for endocrine diseases and nervous system disorders.

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Pyridines and derivatives

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Cayman Chemical PDM 11 Fatty Acids and Derivat Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Apexbio Technology LLC PD-1/PD-L1 inhibitor 1(Synonyms: BMS-202, PD-1/PD-L1 interaction inhibitor 1, PD-L1 inhibitor BMS-202, BMS202), 25mg, CAS: 1675201-83-8. Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Ficerafusp alfa 1mg | 1mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Efizonerimod alfa 5mg | 5mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Lucifer yellow CH (dipotassium salt) | 71206-95-6 | MFCD00013445 | 99.8% | 521.57 | C13H9K2N5O9S2 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Phytohemagglutinin P | 9008-97-3 | MFCD00165279 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Molidustat | 1154028-82-6 | 99.7% | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC CUTC protein, human (His-tag) | >95.0% | 500 UG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 5-PAHSA 100mg | 1481636-41-2 | 538.89 g/mol | C34H66O4 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Methyl 6-amino-6-deoxy-2,3-di-O-tetradecyl-alpha-D-glucopyranoside | 1115270-63-7 | MFCD31813901 | 98.0% | 585.94 g/mol | C35H71NO5 | 25MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Apexbio Technology LLC MHC class II antigen (45-57) [Homo sapiens] 25mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Lactonic sophorolipid | 148409-20-5 | 97.3% | 688.80 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 17α-Hydroxyprogesterone (standard) | 68-96-2 | 99.8% | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More