Pyridines and derivatives
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Filtered Search Results
Medchemexpress LLC (E)-2,3',4,5'-tetramethoxystilbene | 24144-92-1 | MFCD03428621 | 99.4% | 300.35 g·mol^-1 | C18H20O4 | 10 MG
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TMS ((E)-2,3',4,5'-tetramethoxystilbene) is a methylated resveratrol analogue used in research as a selective and competitive inhibitor of cytochrome P450 1B1 (CYP1B1). It shows potent in vitro activity (IC50 ≈ 6 nM, Ki ≈ 3 nM) and is commonly applied in enzymatic assays and cellular studies investigating CYP1B1-related pathways and anti-cancer effects.
- High purity (99.4%) suitable for biochemical assays.
- Soluble in DMSO at ≥ 50 mg/mL for in vitro applications.
- Formulated for in vivo dosing using common vehicle protocols.
- Multiple pack sizes available to support screening and scale-up studies.
- Stable under recommended storage conditions for long-term use.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC SAHM1 | 2050906-89-1 | 96.4% | 2196.58 | 10 MG
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SAHM1 is a peptide mimetic of a dominant negative form of mastermind-like (MAML). It inhibits canonical Notch transcription complex formation and can be used for the research of allergic airway inflammation in mice.
- Inhibits canonical Notch transcription complex formation.
- Used for research of allergic airway inflammation in mice.
- Has an IC50 for Notch.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC MUC5AC motif peptide | 244049-41-0 | 99.0% | 1501.62 | 10 MG
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MUC5AC motif peptide is a 16-amino acid fragment of mucin 5. This peptide mimics the human mucin tandem repeat of MUC5AC.
- For research use only
- Sequence: Gly-Thr-Thr-Pro-Ser-Pro-Val-Pro-Thr-Thr-Ser-Thr-Thr-Ser-Ala-Pro
- Shortened sequence: GTTPSPVPTTSTTSAP
- Appears as a white to off-white solid
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Medchemexpress LLC FAPI-4 | 2374782-02-0 | 99.5% | 872.91 | 10 MG
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FAPI-4 is a potent inhibitor of fibroblast activation protein (FAP), primarily used for targeting FAP in cancer research. Its application in 68Ga-FAPI-4 PET/CT provides a promising diagnostic method for imaging various cancers, demonstrating good tumor-to-background contrast ratios.
- Potent fibroblast activation protein (FAP) inhibitor
- Useful in cancer research
- Promising diagnostic method for imaging various cancers with good tumor-to-background contrast ratios
- For research use only
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eMolecules SALBUTAMOL 500MG
5000189943 SALBUTAMOL 500MG
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Medchemexpress LLC CD300LF MOUSE HEK2 10UG
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5000186058 CD300LF MOUSE HEK2 10UG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000376955 BAY-5516 5MG
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Medchemexpress LLC 1,4-benzothiazepine, 2,3,4,5-tetrahydro-7-methoxy-4-methyl | 927871-76-9 | MFCD12546447 | 99.8% | 209.31 g·mol⁻¹ | C11H15NOS | 10 MG
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S107 is a small-molecule calstabin 2 modulator used in preclinical research. It is orally available and blood-brain barrier permeable, and stabilizes ryanodine receptor 2 (RyR2) channels by enhancing calstabin 2 binding. This mechanism reduces sarcoplasmic reticulum Ca2+ leak and has been evaluated in studies of cardiac arrhythmia and seizure threshold.
- Blood-brain barrier permeable.
- Stabilizes RyR2 channels by enhancing calstabin 2 binding.
- Reduces sarcoplasmic reticulum Ca2+ leak.
- Orally bioavailable in preclinical models.
- High purity solid suitable for research applications.
- Stable powder with recommended cold storage conditions.
- Well characterized chemically (formula C11H15NOS; MW 209.31 g·mol⁻¹).
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Apexbio Technology LLC Alprenolol hydrochloride 13707-88-5 100mg
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Alprenolol hydrochloride (CAS 13707-88-5) is an orally active non-selective -adrenergic receptor antagonist that also exhibits antagonistic effects at 5-HT1A and 5-HT1B receptors By blocking these receptors Alprenolol hydrochloride modulates associated signaling pathways involved in the regulation of cardiovascular functions such as blood pressure control myocardial oxygen demand and cardiac rhythm This compound is utilized in pharmacological research for investigating the physiological mechanisms underlying hypertension angina pectoris and arrhythmias as well as for validating disease models related to these conditions
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000376956 ILORASERTIB 50MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000376957 20-SOLA 50MG
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Medchemexpress LLC β-Apo-13-carotenone (D'Orenone) | 17974-57-1 | MFCD31544340 | 96.5% | 258.40 | C18H26O | 10 MG
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β-Apo-13-carotenone (D'Orenone) is a naturally occurring β-apocarotenoid used in research as an antagonist of the retinoid X receptor alpha (RXRα). It is supplied as a light yellow oil with documented DMSO solubility and is intended for laboratory research use only.
- Acts as an antagonist of RXRα.
- Naturally occurring β-apocarotenoid.
- Light yellow oil appearance.
- High purity (~96.5%) as reported in product documentation.
- Soluble in DMSO at approximately 100 mg/mL; ultrasonic recommended.
- Requires storage at -80°C and protection from light.
- Supplied in small quantities appropriate for in vitro research.
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Medchemexpress LLC RG7697 (NNC0090-2746) | 99.9% | 4473.04 | 10 MG
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RG7697 is a dual agonist for glucagon-like peptide receptor (GLP Receptor) and glucose-dependent insulinotropic polypeptide receptor (GIPR), with EC50 values of 5 pM and 3 pM, respectively. This compound exhibits antihyperglycemic properties and is intended for research use.
- Increases insulin secretion and metabolism
- Decreases glucose excursion
- Ameliorates diet-induced type 2 diabetes and obesity in C57BL/6 mice
- Reduces body weight, blood glucose, and food intake
- Decreases intraperitoneal glucose tolerance, plasma insulin, and cholesterol
- For research use only
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Medchemexpress LLC 2-[(7-methoxy-4-methylquinazolin-2-yl)amino]-4,5-dimethyl-1h-pyrimidin-6-one | 374913-63-0 | MFCD02233199 | 99.2% | 311.34 g·mol⁻¹ | C16H17N5O2 | 10 MG
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Madrasin is a small-molecule inhibitor of pre-mRNA splicing used for research. It prevents formation of splicing intermediates and products in vitro and interferes with early steps of spliceosome assembly; it can also modify splicing of endogenous pre-mRNA in cells. The compound is supplied as a crystalline powder and is typically characterized by high purity and a molecular weight of 311.34 g·mol⁻¹.
- Potent pre-mRNA splicing inhibitor active in vitro.
- Modulates endogenous pre-mRNA splicing in cells.
- High purity suitable for biochemical and cellular assays.
- Typically soluble in DMSO for stock preparation.
- Supplied as a stable crystalline powder for storage and handling.
- Intended for research use only, not for therapeutic use.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000376991 DOMATINOSTAT 10MM 1ML
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