Pyrimidines And Derivatives
Medchemexpress LLC 2,3,4,5-Tetracaffeoyl-D-Glucaric acid | 1419478-52-6 | 5 MG
2,3,4,5-Tetracaffeoyl-D-Glucaric acid is a caffeoyl-D-glucaric acid derivative isolated from the Genus Gnaphalium, intended for research use only.
- Isolated from the genus Gnaphalium
- Purity of 99.29%
- Molecular weight of 858.71
- Formula: C42H34O20
- Appears as an off-white to light yellow solid
- Initial source includes various plants
- Classified as phenylpropanoid
- Soluble in DMSO at 100 mg/mL
- Used in inflammation/immunology research
![eMolecules Medchem Express / ML380 / 5mg / 572596678 / HY-12439 / / 1627138-52-6 / [null] / 494.530 / C23H25F3N4O3S](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502448731.PNG-250.jpg)
eMolecules Medchem Express / ML380 / 5mg / 572596678 / HY-12439 / / 1627138-52-6 / [null] / 494.530 / C23H25F3N4O3S
Medchem Express / ML380 / 5mg / 572596678 / HY-12439 / / 1627138-52-6 / [null] / 494.530 / C23H25F3N4O3S
eMolecules AA Blocks LLC MDK7526 250mg 761906610 AA01CA72 0 000 1448297-52-6 MFCD29049827 430 570 C22H30N4O3S
AA Blocks LLC MDK7526 250mg 761906610 AA01CA72 0 000 1448297-52-6 MFCD29049827 430 570 C22H30N4O3S
![eMolecules Synthonix / 56-Dimethoxybenzo[d]thiazol-2-amine / 100mg / 649425987 / D49737 / / 6294-52-6 / MFCD01663342 / 210.250 / C9H10N2O2S](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502483276.JPG-250.jpg)
eMolecules Synthonix / 56-Dimethoxybenzo[d]thiazol-2-amine / 100mg / 649425987 / D49737 / / 6294-52-6 / MFCD01663342 / 210.250 / C9H10N2O2S
Synthonix / 56-Dimethoxybenzo[d]thiazol-2-amine / 100mg / 649425987 / D49737 / / 6294-52-6 / MFCD01663342 / 210.250 / C9H10N2O2S
eMolecules ChemScene / (3-(Benzylamino)oxetan-3-yl)methanol / 100mg / 572273681 / CS-0053000 / 0.000 / 1195684-52-6 / MFCD18762004 / 193.246 / C11H15NO2
ChemScene / (3-(Benzylamino)oxetan-3-yl)methanol / 100mg / 572273681 / CS-0053000 / 0.000 / 1195684-52-6 / MFCD18762004 / 193.246 / C11H15NO2
Medchemexpress LLC 6-amino-9-benzyl-2-(2-methoxyethoxy)-9H-purin-8-ol | 226907-52-4 | MFCD21648470 | 99.4% | 315.33 g/mol | C15H17N5O3 | 50MG
SM-360320 (CL-087) is a potent, orally active Toll-like receptor 7 (TLR7) agonist used in preclinical research as an immunomodulatory agent with reported antitumor effects. The compound is characterized by CAS 226907-52-4, molecular formula C15H17N5O3, and is supplied as a solid powder with high purity for research use.
Medchemexpress LLC 6-amino-9-benzyl-2-(2-methoxyethoxy)-7H-purin-8-one | 226907-52-4 | MFCD21337856 | 99.4% | 315.33 g/mol | C15H17N5O3 | 25MG
A potent, orally active TLR7 agonist used as an immuno-modulator with reported antitumor activity and adjunct activity in vaccine studies. Supplied as a white to off-white solid, it is used in research to stimulate TLR7-mediated immune responses and to evaluate antiviral and antitumor mechanisms.
- High purity: 99.4%.
- Molecular formula: C15H17N5O3.
- Molecular weight: 315.33 g/mol.
- Appearance: white to off-white solid.
- Function: potent, orally active TLR7 agonist and immuno-modulator.
- Applications: antitumor studies, vaccine adjuvant research, and antiviral assays.
- Packaging: available in multiple solid pack sizes and DMSO solution formats for experimental use.
Medchemexpress LLC 6-amino-7,9-dihydro-2-(2-methoxyethoxy)-9-(phenylmethyl)-8H-purin-8-one | 226907-52-4 | MFCD21648470 | 99.4% | 315.33 g/mol | C15H17N5O3 | 5MG
SM-360320 (CL-087) is a small-molecule Toll-like receptor 7 (TLR7) agonist (CAS 226907-52-4) with immunomodulatory and antitumor activity. Supplied as a white to off-white powder for research use, it is intended for studies requiring TLR7 activation in vitro and in vivo. Handle according to recommended storage and solvent stability conditions.
![Medchemexpress LLC N-ethyl-1-(1H-indazol-5-ylsulfonyl)-N-[(2-(trifluoromethyl)phenyl)methyl]piperidine-4-carboxamide | 1627138-52-6 | 99.9% | 494.53 g/mol | C23H25F3N4O3S | 25MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000236293.png-250.jpg)
Medchemexpress LLC N-ethyl-1-(1H-indazol-5-ylsulfonyl)-N-[(2-(trifluoromethyl)phenyl)methyl]piperidine-4-carboxamide | 1627138-52-6 | 99.9% | 494.53 g/mol | C23H25F3N4O3S | 25MG
ML380 is a potent, subtype-selective, brain-penetrant positive allosteric modulator (PAM) of the M5 muscarinic acetylcholine receptor intended for laboratory research use only. Reported activity includes EC50 ≈190 nM for human M5 and ≈610 nM for rat M5, with moderate selectivity over M1 and M3 subtypes. Typical supplied purity is ≈99.9% and the compound is provided in small milligram packaging for experimental studies.
- Potent M5 mAChR positive allosteric modulator activity (EC50 ≈190 nM human).
- Brain-penetrant profile suitable for central nervous system studies.
- Moderate selectivity versus M1 and M3 receptor subtypes.
- C23H25F3N4O3S, molecular weight 494.53 g/mol.
- High purity (≈99.9%) for reproducible experimental results.
- Available in small milligram quantities for dose-ranging experiments.
Medchemexpress LLC 1-((1H-indazol-5-yl)sulfonyl)-N-ethyl-N-(2-(trifluoromethyl)benzyl)piperidine-4-carboxamide | 1627138-52-6 | >99.0% | 494.53 g/mol | C23H25F3N4O3S | 100MG
ML380 is a potent, brain-penetrant positive allosteric modulator (PAM) of the M5 muscarinic acetylcholine receptor used in research on GPCR signaling and neuronal function. It increases acetylcholine affinity at M5 and displays subtype selectivity (EC50 human ≈190 nM; rat ≈610 nM). CAS: 1627138-52-6.
- Potent positive allosteric modulator of M5 mAChR.
- Subtype-selective with moderate selectivity over M1 and M3.
- Brain-penetrant, suitable for in vivo pharmacology studies.
- High purity (>99.0% by HPLC).
- Molecular formula C23H25F3N4O3S; molecular weight 494.53 g/mol.
- Supplied as a 100 mg solid for research use only.
Medchemexpress LLC 1-((1H-indazol-5-yl)sulfoneyl)-N-ethyl-N-(2-(trifluoromethyl)benzyl)piperidine-4-carboxamide | 1627138-52-6 | 99.9% | 494.53 g/mol | C23H25F3N4O3S | 10MG
ML380 is a subtype-selective, brain-penetrant positive allosteric modulator of the M5 muscarinic acetylcholine receptor used in preclinical research to study M5 receptor pharmacology and central nervous system allosteric modulation. The compound is supplied as a high-purity solid and is available in small research-scale packages and solution formats for laboratory use.
- Subtype-selective M5 mAChR positive allosteric modulator.
- Brain-penetrant profile suitable for CNS studies.
- Reported EC50 values: human M5 190 nM; rat M5 610 nM.
- High purity appropriate for research applications.
- Available in multiple small-scale solid and solution formats.
- Storage recommendations provided for powder and in-solution stability.
Medchemexpress LLC 1-((1H-indazol-5-yl)sulfoneyl)-N-ethyl-N-(2-(trifluoromethyl)benzyl)piperidine-4-carboxamide (ML380) | 1627138-52-6 | 99.9% | 494.53 g/mol | C23H25F3N4O3S | 50MG
ML380 is a potent, subtype-selective, brain-penetrant positive allosteric modulator (PAM) of the M5 muscarinic acetylcholine receptor (mAChR), reported with EC50 ≈190 nM (human) and ≈610 nM (rat). It is supplied for preclinical pharmacology and neuroscience research; molecular formula C23H25F3N4O3S, molecular weight 494.53 g/mol.
- Potent M5 positive allosteric modulator (EC50 ≈190 nM human).
- Moderate selectivity versus M1 and M3 subtypes.
- Brain-penetrant profile suitable for CNS studies.
- High purity (99.87%) for reliable experimental use.
- Soluble in DMSO at 100 mg/mL for formulation and dosing.
- Available in multiple vial sizes to support in vitro and in vivo studies.
Medchemexpress LLC 9H-Purine, 2,6-dichloro-9-β-D-ribofuranosyl- | 13276-52-3 | 321.12 | 250 MG
2,6-Dichloropurine Riboside (CAS 13276-52-3) is a chemical compound with a molecular weight of 321.12 and a purity of 98.97%. It appears as a white to off-white solid and is intended for research use only.
- Chemical name: 9H-Purine, 2,6-dichloro-9-β-D-ribofuranosyl-
- CAS number: 13276-52-3
- Molecular formula: C10H10Cl2N4O4
- Molecular weight: 321.12
- Purity: 98.97%
- Appearance: White to off-white solid
- Storage conditions: -20°C, sealed storage, away from moisture (solid)
- Storage in solvent: -80°C for 6 months; -20°C for 1 month (sealed, away from moisture)
- For research use only
Medchemexpress LLC Ethyl 2-chloropyrimidine-5-carboxylate | 89793-12-4 | 186.60 | 10 G
Ethyl 2-chloropyrimidine-5-carboxylate is a chemical compound commonly used for synthesis in laboratory research. This white to yellow solid is provided for research purposes only.
- Molecular formula: C7H7ClN2O2
- Molecular weight: 186.60
- CAS number: 89793-12-4
- Purity: 99.7%
- Identified uses: Laboratory chemicals, manufacture of substances
- Appearance: Solid, white to yellow
- Melting/freezing point: 52-60°C
- Boiling point: 314.2°C at 760 mmHg
- Stable under recommended storage conditions
- Storage: 4°C, sealed storage, away from moisture; in solvent: -80°C, 6 months; -20°C, 1 month