Pyrroles
Medchemexpress LLC Ethyl 2-amino-4-methyl-5-((3-nitrophenyl)carbamoyl)-thiophene-3-carboxylate | 303141-21-1 | 99.7% | 10 MG
DC-S239 is a selective inhibitor of histone methyltransferase SET7 with reported in vitro activity (IC50 = 4.59 μM); supplied as a high-purity solid for research use.
- Selective SET7 inhibitor with IC50 = 4.59 μM.
- Reported antiproliferative activity in MCF7 and HL60 cells.
- High purity suitable for biochemical and cellular studies.
- Soluble in DMSO (125 mg/mL) for in vitro experiments.
- Stable as a powder at -20°C for long-term storage.
![Medchemexpress LLC Ethyl 2-amino-4-methyl-5-[(3-nitrophenyl)formamido]thiophene-3-carboxylate | 303141-21-1 | 99.7% | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000233735.png-250.jpg)
Medchemexpress LLC Ethyl 2-amino-4-methyl-5-[(3-nitrophenyl)formamido]thiophene-3-carboxylate | 303141-21-1 | 99.7% | 50 MG
DC-S239 is a selective small-molecule inhibitor of the histone methyltransferase SET7 (SETD7) used for research applications. It is reported to inhibit SET7 with an IC50 of 4.59 μM and is supplied as a solid for laboratory use.
- Selective SET7 inhibitor with reported IC50 of 4.59 μM.
- High purity (99.7%).
- Molecular weight 349.36 g/mol; formula C15H15N3O5S.
- Solid, yellow-orange physical form suitable for handling and storage.
- Available as a 50 mg research vial.
Medchemexpress LLC HY-112180 10mg Medchemexpress, JNJ-678 CAS:1383450-81-4 Purity:>98%
Medchemexpress, HY-112180 10mg JNJ-678 CAS:1383450-81-4 JNJ-678 (JNJ-53718678) is a novel fusion protein inhibitor in clinical trials for the treatment of respiratory syncytial virus (RSV). Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC UNC2025 hydrochloride | 2070015-17-5 | 100.0% | 513.12 | C28H41ClN6O | 25MG
UNC2025 hydrochloride is the hydrochloride salt of UNC2025, a potent, ATP-competitive, orally active dual Mer (MERTK) and FLT3 kinase inhibitor used in preclinical oncology research. It exhibits sub-nanomolar potency and favorable pharmacokinetic properties, and is supplied as a light yellow solid for laboratory use.
- Potent Mer and FLT3 inhibition (IC50 0.74 nM and 0.8 nM).
- High reported purity (99.96%).
- Solid form with light yellow to yellow appearance.
- Demonstrated >45-fold selectivity for MERTK versus Axl.
- Available in multiple pack sizes and solution aliquots for flexible dosing.
- Useful as a tool compound in preclinical oncology models, including acute leukemia research.
eMolecules 931706-15-9 | Medchem Express | PPQ-102 | 5mg | 446263909 | HY-14179 | MFCD14824240 | 438.487 | C26H22N4O3
Medchem Express | PPQ-102 | 5mg | 446263909 | HY-14179 | 931706-15-9 | MFCD14824240 | 438.487 | C26H22N4O3
Medchemexpress LLC HY-15573 5mg Medchemexpress, EI1 CAS:1418308-27-6 Purity:>98%
Medchemexpress, HY-15573 5mg EI1 CAS:1418308-27-6 EI1 (KB-145943) is a potent and selective EZH2 inhibitor with IC50 of 15 nM and 13 nM for EZH2 (WT) and EZH2 (Y641F), respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-12747 5mg Medchemexpress, DC_517 CAS:500017-70-9 Purity:>98%
Medchemexpress, HY-12747 5mg DC_517 CAS:500017-70-9 DC_517 is a DNA methyltransferase 1 (DNMT1) inhibitor, with an IC50 and a Kd of 1.7 μM and 0.91 μM, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-52101 25mg , CMK CAS:821794-90-5 Purity:98%
Medchemexpress, HY-52101 25mg CMK CAS:821794-90-5 Formula:C18H19ClN4O2 Purity:98% CMK is a RSK2 kinase inhibitor, used for cancer treatment. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
eMolecules 1594092-37-1 | Medchem Express | AZ191 | 5mg | 446260910 | HY-12277 | MFCD28015098 | 429.528 | C24H27N7O
Ambeed | 12H-Benzo[45]thieno[23-a]carbazole | 250mg | 682928390 | A1150534 | 222-21-9 | MFCD30291519 | 273.350 | C18H11NS
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Medchemexpress LLC Ac-feid-cmk (TFA) | 97.1% | 711.08 | 5 MG
Ac-FEID-CMK TFA is a potent zebrafish-specific GSDMEb-derived peptide inhibitor. It inhibits pyroptosis and attenuates septic acute kidney injury (AKI) in vivo, and can suppress the caspy2-mediated noncanonical inflammasome pathway.
- Attenuates mortality during septic shock
- Reduces kidney injury during septic shock
- Inhibits pyroptosis
- Suppresses caspy2-mediated noncanonical inflammasome pathway
Medchemexpress LLC HY-123918 5mg Medchemexpress, JMS-17-2 CAS:1380392-05-1 Purity:>98%
Medchemexpress, HY-123918 5mg JMS-17-2 CAS:1380392-05-1 JMS-17-2 is a potent and selective CX3CR1 antagonist with an IC50 of 0.32 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.