Pyrroles
Apexbio Technology LLC Malate-Colori-Assay-Kit
Malate Colorimetric Assay Kit is a biochemical tool used in metabolic and enzymatic research to measure malate levels originating from studies on cellular respiration and the tricarboxylic acid (TCA) cycle This kit operates by utilizing colorimetric detection which involves converting malate to a detectable colored compound through enzymatic reactions providing insights into pathway dynamics It demonstrates in vitro activity in the nanomolar to low micromolar range facilitating detailed metabolic profiling Typically employed in cell models and biochemical assays it is valuable in drug screening and analyzing metabolic alterations in various conditions Experimental concentrations typically depend on the specific research design This kit aids in understanding cellular metabolism offering vital information for researchers focusing on energy production and metabolic disorders
Medchemexpress LLC (-)-G-Lactone | 43119-28-4 | ≥98.0% | 124.14 | 100 MG
(-)-G-Lactone is a synthetic intermediate useful for prostaglandins synthesis. It is intended for research use only.
- Synthetic intermediate
- Useful for prostaglandins synthesis
Medchemexpress LLC Compound 48/80 trihydrochloride | 848035-21-2 | 99.8% | C32H48Cl3N3O3 | 10MG
Compound 48/80 trihydrochloride is an oligomeric mixture formed by condensation of N-methyl-p-methoxyphenethylamine with formaldehyde. It is used in research to trigger mast cell degranulation and histamine release and has been reported to inhibit phosphatidylinositol-specific phospholipase C activity.
- Used to induce mast cell degranulation and histamine release
- Oligomeric mixture with molecular formula C32H48Cl3N3O3 and MW 629.10 g·mol⁻¹
- High supplied purity (approximately 99.8%) suitable for research
- Available in multiple small mass pack sizes and as a 10 mM aqueous solution
- Storage: keep solid at 4°C sealed and protect from moisture; in solvent store at -20°C to -80°C for long term
Medchemexpress LLC Pravastatin lactone | 85956-22-5 | 99.2% | 5 MG
Pravastatin lactone is the delta-lactone metabolite of pravastatin and a potent inhibitor of HMG-CoA reductase. It is used as a research reagent to study statin metabolism and cholesterol biosynthesis in biochemical and pharmacological assays.
- Potent HMG-CoA reductase inhibitor used in cholesterol synthesis studies.
- High purity suitable for analytical and biochemical applications.
- Available in small milligram quantities for assay development and metabolism studies.
- Molecular formula C23H34O6 and molecular weight 406.51 g/mol aid identification and dosing.
- Provided as a neat solid for laboratory research use.
Selleck Chemical LLC Almotriptan Malate S2096-10mg
Almotriptan Malate (LAS 31416) is a selective 5-hydroxytryptamine1B/1D (5-HT1B/1D) receptor agonist used for the treatment of Migraine attacks in adults
Medchemexpress LLC Bromoenol lactone | 88070-98-8 | MFCD00270871 | ≥98.0% | 317.18 g/mol | C16H13BrO2 | 10 MG
Bromoenol lactone is a suicide-based, irreversible inhibitor of calcium-independent phospholipase A2 (iPLA2β) used in biochemical research. It inhibits iPLA2β with an IC50 of approximately 7 μM and has been reported to block antigen-stimulated mast cell exocytosis without affecting Ca2+ influx. The compound is supplied as a solid for laboratory preparation of stock solutions.
- Irreversible mechanism-based inhibitor of iPLA2β.
- Reported IC50 of approximately 7 μM.
- Useful for studying phospholipase A2-mediated signaling and mast cell exocytosis.
- Available as a solid suitable for solution preparation.
- Molecular weight 317.18 g/mol; molecular formula C16H13BrO2.
TARGETMOL CHEMICALS INC 2-HYDROXY ATORVASTATIN C 5MG
Also available in 1 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. 2-Hydroxy atorvastatin calcium salt is a hydroxy metabolite of Atorvastatin calcium salt which is a potent HMG-CoA reductase inhibitor (IC50 = 8 nM). purity: 97%
=O)C(O)=O.CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c1C | 100mg | 335409657](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000130170.jpg-250.jpg)
eMolecules 341031-54-7 | Sunitinib Malate | Target Molecule | MFCD08282795 | 532.569 | C26H33FN4O7 | 0.000 | O[C@@H](CC(O)=O)C(O)=O.CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c1C | 100mg | 335409657
Sunitinib Malate | Target Molecule | 341031-54-7 | MFCD08282795 | 532.569 | C26H33FN4O7 | 0.000 | O[C@@H](CC(O)=O)C(O)=O.CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c1C | 100mg | 335409657
eMolecules 1129403-56-0 | Medchem Express | Amcasertib | 5mg | 446268712 | HY-17602 | MFCD30489231 | 539.7 | C31H33N5O2S
Ambeed | (S)-33-Dibromo-11-bi-2-naphthol | 250mg | 588342535 | A390911 | 119707-74-3 | MFCD03093629 | 444.122 | C20H12Br2O2
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Apexbio Technology LLC Sunitinib malate(Synonyms: Sutent, SU11248, Sunitinib L-malate, Sunitinib malate salt, SU-11248 malate, Sutent malate), 2g, CAS: 341031-54-7.
Sunitinib malate (CAS 341031-54-7) is a small molecule orally bioavailable multitargeted receptor tyrosine kinase inhibitor It inhibits various receptor tyrosine kinases including platelet-derived growth factor receptor (PDGFR) vascular endothelial growth factor receptors (VEGFR-1 2 and 3) c-KIT FLT3 kinase colony-stimulating factor-1 receptor (CSF-1R) and RET kinase In neuroblastoma cell lines (e g SK-N-BE(2) SH-SY5Y LAN-5) treatment with sunitinib malate significantly suppresses proliferation in a dose-dependent manner (IC50 10-20 ng/ml) Preclinical studies show tumor growth inhibition and reduced metastasis in neuroblastoma mouse models highlighting its potential for research in oncology therapeutics
Medchemexpress LLC Pizotifen malate | 5189-11-7 | 99.0% | C23H27NO5S | 100 MG
Pizotifen malate (Pizotyline malate) is a potent 5-HT2 receptor antagonist with high affinity for the 5-HT1C binding site. It acts as an antidepressant 5-HT2A receptor antagonist, capable of inhibiting serotonin-enhanced ADP-induced platelet aggregation. This product is intended for research use only and is not sold to patients.
- Potent 5-HT2 receptor antagonist
- High affinity for the 5-HT1C binding site
- Antidepressant 5-HT2A receptor antagonist
- Inhibits serotonin-enhanced ADP-induced platelet aggregation
- Intended for research use only
Medchemexpress LLC Compound 48/80 trihydrochloride | 848035-21-2 | 1 ML
Compound 48/80 trihydrochloride (C48/80 trihydrochloride) is a mixture of condensation products of N-methyl-p-methoxyphenethylamine with formaldehyde. It acts as a histamine releaser and a mast cell degranulator. This compound inhibits phosphatidylinositol-specific phospholipase C activity from human platelets, with IC50 values of 2.1 μg/ml (supernatant) and 5.0 μg/ml (particulate fraction). It also inhibits the aggregation of human platelets induced by ADP and PAF-acether.
- Acts as a histamine releaser and mast cell degranulator.
- Inhibits phosphatidylinositol-specific phospholipase C activity.
- Inhibits human platelet aggregation induced by ADP and PAF-acether.
- Increases serum serotonin, histamine, and corticosterone levels in vivo.
- Causes oxidative stress in rat adrenal glands through mast cell degranulation.
Cayman Chemical 4-hydroxy Atorvastatin calci
A metabolite of atorvastatin; formed by metabolism of atorvastatin by CYP3A4