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Filtered Search Results
Aobchem AOBCHEM
5000916547 2 2 2-TRIFLUORO-1- 2- PYRROLID
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![Medchemexpress LLC Glycine, N-[(1,1-dimethylethoxy)carbonyl]-L-valylglycine | 45233-75-8 | MFCD00134861 | 97.0% | 274.31 | C12H22N2O5 | 5 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000299761.png-250.jpg)
Medchemexpress LLC Glycine, N-[(1,1-dimethylethoxy)carbonyl]-L-valylglycine | 45233-75-8 | MFCD00134861 | 97.0% | 274.31 | C12H22N2O5 | 5 G
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Tert-butoxycarbonyl-L-valylglycine is a Boc-protected dipeptide derivative of glycine supplied as a white to off-white solid for research use. It is used as a building block in peptide synthesis and related biochemical studies where protected amino acid derivatives are required. The material has a molecular weight of 274.31 g/mol and a reported purity of 97.0%.
- Boc-protected dipeptide suitable for peptide synthesis.
- White to off-white solid for easy handling.
- Molecular weight 274.31 g/mol.
- Molecular formula C12H22N2O5.
- Purity 97.0% as stated by supplier.
- Available in small-scale quantities for research use.
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Aobchem AOBCHEM
5001093403 4-FLUORO-3- PYRROLIDINE-1-CARB
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Chemscene CHEMSCENE
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5000579232 1-BOC-4-BROMOMETHYLPIPERIDI 1G
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Medchemexpress LLC Boc-NH-PEG7-propargyl | 2112737-90-1 | C22H41NO9 | 250 MG
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Boc-NH-PEG7-propargyl is a PEG-based PROTAC linker primarily used in the synthesis of PROTACs. It functions as a click chemistry reagent, featuring an alkyne group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing azide groups. This compound is instrumental in constructing PROTACs, which are designed to selectively degrade target proteins by exploiting the intracellular ubiquitin-proteasome system.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Contains an alkyne group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules
- Exploits the intracellular ubiquitin-proteasome system for target protein degradation
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Medchemexpress LLC (S,S,S,S,R)-Boc-Dap-NE | 3026594-75-9 | 99.8% | 50 MG
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(S,S,S,S,R)-Boc-Dap-NE is a Boc-protected diaminopropane derivative used as an intermediate in the synthesis of monomethyl auristatin E (MMAE) and related auristatin analogs. It is supplied as a purified solid for research and medicinal chemistry synthesis.
- High purity: 99.8%.
- Molecular formula: C23H36N2O5.
- Molecular weight: 420.54 g/mol.
- Physical form: off-white to white powder, stored under inert gas.
- Common pack sizes: 25 MG, 50 MG, 100 MG (availability may vary).
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eMolecules 426842-70-8 | 4-Allyl-1-(tert-butoxycarbonyl)piperidine-4-carboxylic acid | Oakwood Chemical | MFCD02179130 | 269.341 | C14H23NO4 | 98.000 | CC(C)(C)OC(=O)N1CCC(CC=C)(CC1)C(O)=O | 1g | 537722977
4-Allyl-1-(tert-butoxycarbonyl)piperidine-4-carboxylic acid | Oakwood Chemical | 426842-70-8 | MFCD02179130 | 269.341 | C14H23NO4 | 98.000 | CC(C)(C)OC(=O)N1CCC(CC=C)(CC1)C(O)=O | 1g | 537722977
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Medchemexpress LLC Azido-PEG4-CH2-Boc | 864681-04-9 | ≥97.0% | 333.38 g/mol | C14H27N3O6 | 500 MG
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Azido-PEG4-CH2-Boc is a Boc-protected, azide-functionalized PEG4 linker designed for bioconjugation and linker synthesis in research applications. It provides an azide handle for click chemistry and a Boc-protected amine for downstream modification.
- Azide functionality compatible with copper-catalyzed and strain-promoted click reactions.
- Boc-protected amine handle for controlled deprotection and conjugation.
- Four-unit PEG spacer for improved solubility and flexibility in conjugates.
- Suitable for ADC and PROTAC linker development and general bioconjugation workflows.
- High purity and defined molecular weight support reproducible synthetic results.
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Ambeed AMBEED
5000849394 N-BOC-1 6-DIAMINOHEXANE 10G
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Medchemexpress LLC Z-FF-FMK | 105608-85-3 | 96.0% | C27H27FN2O4 | 25 MG
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Z-FF-FMK is a selective cathepsin-L inhibitor. It can prevent β-amyloid from inducing apoptotic changes such as activation of caspase-3, cleavage of the DNA repair enzyme, poly-ADP ribose polymerase, and DNA fragmentation.
- Selective cathepsin-L inhibitor
- Prevents β-amyloid induced apoptotic changes
- Inhibits caspase-3 activation
- Cleavage of DNA repair enzyme, poly-ADP ribose polymerase, and DNA fragmentation
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Medchemexpress LLC Boc-amido-PEG9-amine | 890091-43-7 | ≥98.0% | C25H52N2O11 | 250 MG
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Boc-amido-PEG9-amine is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs operate by utilizing the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Utilizes intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- Not for sale to patients
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Medchemexpress LLC PROTAC ERRα Degrader-3 | 2306388-65-6 | 98.7% | 956.99 | 100 MG
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PROTAC ERRα Degrader-3 is a potent and selective ERRα degrader based on von Hippel-Lindau ligand. It is capable of specifically degrading ERRα protein by >80% at a concentration of 30 nM and is inactive against ERRβ and ERRγ proteins. It is for research use only.
- Potent and selective ERRα degrader
- Dose-dependently induces ERRα degradation
- Decreases protein levels of ERRα downstream target genes (ATP5B, MCAD, PDK4)
- Blocks protein-protein interaction of ERRα with PGC-1α peptide
- Induces approximately 96% protein degradation at 100 nM
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Aobchem AOBCHEM
5001004458 3-METHOXY-4- PYRROLIDINE-1-CA
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Medchemexpress LLC Boc-N-PEG1-C2-NHS ester | 1260092-55-4 | 97.0% | C14H22N2O7 | 10 G
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Boc-N-PEG1-C2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs (Proteolysis Targeting Chimeras) contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Peg-based PROTAC linker
- Used in the synthesis of PROTACs
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC N-Boc-PEG1-bromide | 164332-88-1 | 97.9% | 268.15 | C9H18BrNO3 | 250 MG
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N-Boc-PEG1-bromide is a Boc-protected PEG1 bromide reagent used as a short, hydrophilic linker for conjugation chemistry, including antibody-drug conjugate (ADC) and PROTAC linker synthesis. It provides a terminal bromide for alkylation or nucleophilic substitution and a Boc-protected amino group for orthogonal protection strategies.
- Provides a short PEG spacer to increase solubility.
- Contains a terminal bromide for alkylation and substitution reactions.
- Includes a Boc-protected amino group for orthogonal deprotection.
- Used in ADC and PROTAC linker synthesis and general conjugation chemistry.
- Supplied in multiple package sizes for research use.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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