Pyrrolidines

Organic heterocyclic compounds that consist of a five-membered ring with four carbon atoms and one nitrogen atom that form a cyclic secondary amine.

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4,396 – 4,410 of 6,328 results

4,396

eMolecules 1303972-81-7 | 1-(tert-Butoxycarbonyl)-3,3-difluoropiperidine-4-carboxylic acid | ChemScene | MFCD18909780 | 265.257 | C11H17F2NO4 | 97.000 | CC(C)(C)OC(=O)N1CCC(C(O)=O)C(F)(F)C1 | 100mg | 346751360

1-(tert-Butoxycarbonyl)-3,3-difluoropiperidine-4-carboxylic acid | ChemScene | 1303972-81-7 | MFCD18909780 | 265.257 | C11H17F2NO4 | 97.000 | CC(C)(C)OC(=O)N1CCC(C(O)=O)C(F)(F)C1 | 100mg | 346751360

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4,397

Medchemexpress LLC (Rac)-XL177A | 2417089-73-5 | 99.6% | 861.47 | 1 ML

(Rac)-XL177A is the racemic isomer of XL177A, a highly potent and selective irreversible USP7 inhibitor with an IC50 of 0.34 nM. This compound suppresses cancer cell growth predominantly through a p53-dependent mechanism.

Potent and selective irreversible USP7 inhibitor
Exhibits an IC50 of 0.34 nM
Suppresses cancer cell growth
Acts through a p53-dependent mechanism
Racemic isomer

Pricing & Availability

4,398

Medchemexpress LLC Azido-PEG6-MS | 352439-38-4 | 95.3% | 385.43 | 25 MG

Azido-PEG6-MS is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. This compound functions as a click chemistry reagent, incorporating an azide group that enables it to participate in copper-catalyzed azide-alkyne cycloaddition reactions with molecules possessing alkyne groups. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition reactions with molecules containing DBCO or BCN groups.

It is a PEG-based PROTAC linker.
It can be used in the synthesis of PROTACs.
It is a click chemistry reagent.
It contains an azide group.
It can undergo copper-catalyzed azide-alkyne cycloaddition reactions with molecules containing alkyne groups.
It can also undergo strain-promoted alkyne-azide cycloaddition reactions with molecules containing DBCO or BCN groups.

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4,399

eMolecules 942518-20-9 | (2S)-N-Fmoc-4-azido-butanoic acid | Combi-Blocks | MFCD11052920 | 366.377 | C19H18N4O4 | 97.000 | OC(=O)[C@H](CCN=[N+]=[N-])NC(=O)OCC1c2ccccc2-c2ccccc12 | 1g | 232325392

(2S)-N-Fmoc-4-azido-butanoic acid | Combi-Blocks | 942518-20-9 | MFCD11052920 | 366.377 | C19H18N4O4 | 97.000 | OC(=O)[C@H](CCN=[N+]=[N-])NC(=O)OCC1c2ccccc2-c2ccccc12 | 1g | 232325392

Pricing & Availability

4,400

Medchemexpress LLC (Rac)-LY341495 | 96.5% | C20H19NO5 | 10 MM * 1 ML

(Rac)-LY341495 is an isomer of LY341495 and can be utilized as a control compound in experiments. The parent compound, LY341495, functions as a metabotropic glutamate receptor (mGluR) antagonist, exhibiting IC50 values of 21 nM for mGlu2, 14 nM for mGlu3, 7.8 μM for mGlu1a, 8.2 μM for mGlu5a, 170 nM for mGlu8, 990 nM for mGlu7, and 22 μM for mGlu4 receptors.

Isomer of LY341495.
Can be used as a control compound in experiments.
LY341495 is a metabotropic glutamate receptor (mGluR) antagonist.
Molecular weight: 353.37
Appearance: Solid
Color: White to off-white
For research use only.

Pricing & Availability

4,401

Medchemexpress LLC (R)-Pyrrolidine-3-carboxylic acid | 72580-54-2 | 97.0% | C5H9NO2 | 5 G

(R)-Pyrrolidine-3-carboxylic acid is a proline derivative and an amino acid derivative. Amino acids and their derivatives are often used as ergogenic supplements. They are known to influence anabolic hormone secretion, provide fuel during exercise, improve mental performance during stress-related tasks, and help prevent exercise-induced muscle damage.

Proline derivative
Functions as an ergogenic supplement
Influences anabolic hormone secretion
Supplies fuel during exercise
Enhances mental performance during stress
Helps prevent exercise-induced muscle damage

Pricing & Availability

4,402

Medchemexpress LLC (Rac)-Etavopivat | 2622070-93-1 | 99.9% | 457.50 | 100 MG

This product is an isomer of Etavopivat. Etavopivat is an orally active erythrocyte pyruvate kinase-R activator that can be used in studies of sickle cell disease and other haemoglobinopathies. For research use only.

Improves haemoglobin-oxygen affinity and reduces the sickle point in human red blood cells.
Causes an increase in 2,3-DPG and ATP in crab-eating monkeys.

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4,403

Medchemexpress LLC (Rac)-P1D-34 | 2957895-04-2 | 99.5% | 10 MG

(Rac)-P1D-34 is a racemic PROTAC degrader that induces degradation of the peptidyl-prolyl isomerase Pin1 in cellular models. It has been characterized in biochemical and cell-based studies showing Pin1 loss, downstream client protein modulation, antiproliferative activity in leukemia lines, and induction of apoptosis and DNA damage.

Pricing & Availability

4,404

Medchemexpress LLC Azido-PEG12-acid | 2152679-71-3 | 99.8% | C27H53N3O14 | 50 MG

Azido-PEG12-acid is a PEG-based PROTAC linker used in the synthesis of PROTACs. It functions as a click chemistry reagent containing an Azide group, enabling both copper-catalyzed azide-alkyne cycloaddition (CuAAc) with Alkyne groups and strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups. PROTACs leverage the ubiquitin-proteasome system to selectively degrade target proteins.

PEG-based PROTAC linker
Used in the synthesis of PROTACs
Click chemistry reagent with Azide group
Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc)
Participates in strain-promoted alkyne-azide cycloaddition (SPAAC)
PROTACs utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins

Pricing & Availability

4,405

Medchemexpress LLC Rac-lanicemine (AZD6765) | 61890-25-3 | MFCD00924222 | 99.6% | 198.27 g/mol | C13H14N2 | 1 ML

(Rac)-Lanicemine is the racemic form of lanicemine (AZD6765), a low-trapping NMDA receptor channel blocker used in neuroscience research. Supplied as a concentrated solution for in vitro and analytical applications, it is intended for use under appropriate laboratory safety conditions and storage recommendations.

Racemic NMDA receptor antagonist for neuropharmacology studies.
Supplied as a concentrated solution for direct use in assays.
High chemical purity suitable for analytical applications.
Stable when stored according to recommended conditions.
Provided with product documentation such as datasheet and certificate of analysis.

Pricing & Availability

4,406

Sigma Aldrich Fine Chemicals Biosciences Kainic acid monohydrate >=98% (HPLC), from Digenea simplex | 58002-62-3 | MFCD00150833 | 10MG

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4,407

Medchemexpress LLC Azido-methyltetrazine di-arm linker | 2861998-16-3 | 440.50 g·mol⁻¹ | C20H28N10O2 | 100 MG

Azido-methyltetrazine di-arm linker is a bifunctional small-molecule linker designed for constructing multivalent antibody-drug conjugates (ADCs). It provides an azide handle and a methyltetrazine moiety to enable orthogonal bioorthogonal conjugation strategies for site-selective payload attachment in chemical biology and ADC development.

Bifunctional linker with azide and methyltetrazine groups.
Enables rapid inverse-electron-demand Diels-Alder ligation.
Compatible with click chemistry for selective payload attachment.
Supplied as a solid in multiple small-scale quantities for research use.
Molecular formula C20H28N10O2; molecular weight 440.5 g·mol⁻¹.

Pricing & Availability

4,408

eMolecules 1257063-35-6 | Azido-PEG4-C2-acid | ChemScene | MFCD12406155 | 291.304 | C11H21N3O6 | 97.000 | OC(=O)CCOCCOCCOCCOCCN=[N+]=[N-] | 100mg | 642097009

Azido-PEG4-C2-acid | ChemScene | 1257063-35-6 | MFCD12406155 | 291.304 | C11H21N3O6 | 97.000 | OC(=O)CCOCCOCCOCCOCCN=[N+]=[N-] | 100mg | 642097009

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4,409

Medchemexpress LLC (Rac)-minzasolmin | 1802518-63-3 | 99.9% | 425.59 g/mol | C23H31N5OS | 10MG

(Rac)-Minzasolmin is a racemic, brain-penetrant inhibitor of α-synuclein misfolding developed for research into synucleinopathies. It modulates early-stage aggregation, can revert membrane-bound oligomers to monomers, and has shown efficacy in α-synuclein transgenic models relevant to Parkinson's disease and dementia with Lewy bodies.

Brain-penetrant small molecule suitable for in vivo and in vitro studies.
Inhibits α-synuclein misfolding and early-stage aggregation.
Promotes reversion of membrane-bound oligomers to monomers.
Demonstrated activity in α-synuclein transgenic models.
High purity for research use (≈99.9%).
Molecular formula C23H31N5OS; molecular weight 425.59 g/mol.

Pricing & Availability

4,410

Medchemexpress LLC N-(1-((2R,3R,4R,5R)-3-((tert-Butyldimethylsilyl)oxy)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-ox | 401812-97-3 | C17H29N3O6Si | 250 MG

N-(1-((2R,3R,4R,5R)-3-((tert-Butyldimethylsilyl)oxy)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)acetamide is a chemical compound primarily utilized as a drug intermediate. It is crucial for the synthesis of various active compounds. This product is intended for research use only and has not been fully validated for medical applications.

Drug intermediate target
Used for synthesis of various active compounds

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Pyrrolidines

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Medchemexpress LLC (Rac)-XL177A | 2417089-73-5 | 99.6% | 861.47 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Azido-PEG6-MS | 352439-38-4 | 95.3% | 385.43 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC (Rac)-LY341495 | 96.5% | C20H19NO5 | 10 MM * 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC (R)-Pyrrolidine-3-carboxylic acid | 72580-54-2 | 97.0% | C5H9NO2 | 5 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC (Rac)-Etavopivat | 2622070-93-1 | 99.9% | 457.50 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC (Rac)-P1D-34 | 2957895-04-2 | 99.5% | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Azido-PEG12-acid | 2152679-71-3 | 99.8% | C27H53N3O14 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Rac-lanicemine (AZD6765) | 61890-25-3 | MFCD00924222 | 99.6% | 198.27 g/mol | C13H14N2 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Azido-methyltetrazine di-arm linker | 2861998-16-3 | 440.50 g·mol⁻¹ | C20H28N10O2 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC (Rac)-minzasolmin | 1802518-63-3 | 99.9% | 425.59 g/mol | C23H31N5OS | 10MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC N-(1-((2R,3R,4R,5R)-3-((tert-Butyldimethylsilyl)oxy)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-ox | 401812-97-3 | C17H29N3O6Si | 250 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More