(S,R,S)-AHPC-PEG5-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 5-unit PEG linker, commonly used in PROTAC technology. It functions by recruiting the VHL protein, a key substrate recognition subunit of Cullin RING E3 ubiquitin ligase complexes, to induce ubiquitination and subsequent proteasomal degradation of target proteins.
- Synthesized E3 ligase ligand-linker conjugate
- Incorporates (S,R,S)-AHPC based VHL ligand
- Includes 5-unit PEG linker
- Used in PROTAC technology
- Recruits VHL protein to induce ubiquitination
- Promotes proteasomal degradation of target proteins
- For research use only