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Pyrrolidines

Organic heterocyclic compounds that consist of a five-membered ring with four carbon atoms and one nitrogen atom that form a cyclic secondary amine.

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1

Medchemexpress LLC N-Arachidonyl maleimide | 876305-42-9 | 98.31% | 369.54 | 10 MG
SDP

N-Arachidonyl maleimide is a potent, irreversible inhibitor of monoacylglycerol lipase (MAGL) with an IC50 value of 140 nM. It modulates the effects of 2-arachidonyl glycerol (2-AG) by increasing endogenous levels of 2-AG in the brain and preventing cerebellar membrane-mediated degradation of 2-AG.

  • Potent, irreversible inhibitor of monoacylglycerol lipase (MAGL)
  • Modulates effects of 2-arachidonyl glycerol (2-AG)
  • Increases endogenous levels of 2-AG in the brain
  • Prevents cerebellar membrane-mediated degradation of 2-AG
  • Produces hypothermia, inhibition of locomotor activity, antinociception, and catalepsy in vivo

ENCOMPASS_PREFERRED
2

Medchemexpress LLC N-Arachidonyl maleimide | 876305-42-9 | 98.3% | 369.54 | 100 MG
SDP

N-Arachidonyl maleimide is a potent, irreversible inhibitor of monoacylglycerol lipase (MAGL) with an IC50 value of 140 nM. It is a putative MAGL inhibitor that modulates the effects of 2-arachidonyl glycerol (2-AG), increasing endogenous levels of 2-AG in the brain and preventing cerebellar membrane-mediated degradation of 2-AG.

  • Modulates the effects of 2-arachidonyl glycerol (2-AG)
  • Increases endogenous levels of 2-AG in the brain
  • Prevents cerebellar membrane-mediated degradation of 2-AG
  • For research purposes only

ENCOMPASS_PREFERRED
3

Medchemexpress LLC N-Arachidonyl maleimide | 876305-42-9 | 98.31% | 369.54 | 25 MG
SDP

N-Arachidonyl maleimide is a potent, irreversible inhibitor of monoacylglycerol lipase (MAGL) with an IC50 value of 140 nM. It can be used to modulate the effects of 2-arachidonyl glycerol (2-AG) by increasing its endogenous levels in the brain, and it prevents cerebellar membrane-mediated degradation of 2-AG.

  • Potent, irreversible MAGL inhibitor
  • Modulates effects of 2-arachidonyl glycerol (2-AG)
  • Increases endogenous levels of 2-AG in the brain
  • Prevents cerebellar membrane-mediated degradation of 2-AG

ENCOMPASS_PREFERRED
4

Medchemexpress LLC N-Arachidonyl maleimide | 876305-42-9 | 98.3% | 369.54 | 1 ML
SDP

N-Arachidonyl maleimide is a potent, irreversible inhibitor of monoacylglycerol lipase (MAGL) with an IC50 value of 140 nM. It modulates the effects of 2-arachidonyl glycerol (2-AG) by increasing its endogenous levels in the brain and preventing cerebellar membrane-mediated degradation.

  • Potent and irreversible monoacylglycerol lipase (MAGL) inhibitor
  • Modulates effects of 2-arachidonyl glycerol (2-AG)
  • Increases endogenous levels of 2-AG in the brain
  • Prevents cerebellar membrane-mediated degradation of 2-AG
  • Induces hypothermia, antinociception, and catalepsy in vivo when combined with 2-AG

ENCOMPASS_PREFERRED
5

Medchemexpress LLC N-Arachidonyl maleimide | 876305-42-9 | 98.3% | 369.54 | 50 MG
SDP

N-Arachidonyl maleimide is a potent, irreversible inhibitor of monoacylglycerol lipase (MAGL) with an IC50 value of 140 nM.

  • Modulates effects of 2-arachidonyl glycerol (2-AG) by increasing endogenous levels of 2-AG in the brain
  • Prevents cerebellar membrane-mediated degradation of 2-AG
  • Produces dose-dependent hypothermia when combined with 2-AG
  • Inhibits locomotor activity when combined with 2-AG
  • Causes antinociception when combined with 2-AG
  • Induces catalepsy when combined with 2-AG

ENCOMPASS_PREFERRED
6

Medchemexpress LLC Protac BRD4 degrader-9 | 2417370-42-2 | 98.2% | 1312.50 g/mol | C59H71F2N9O15S4 | 5 MG
SDP

Protac BRD4 degrader-9 is a BRD4-targeting PROTAC small-molecule degrader provided for research use in targeted protein degradation and epigenetic studies. It is supplied as a powder with recommended frozen storage and is intended for biochemical and cellular assays.

  • Target: BRD4.
  • Molecular formula: C59H71F2N9O15S4.
  • Molecular weight: 1312.50 g/mol.
  • Purity: 98.2%.
  • Recommended storage: powder at -20°C; in solvent at -80°C (6 months) or -20°C (1 month).

ENCOMPASS_PREFERRED
7

Medchemexpress LLC Protac BRD4 degrader-9 | 2417370-42-2 | 98.2% | 1312.50 g/mol | C59H71F2N9O15S4 | 1 MG
SDP

PROTAC BRD4 Degrader-9 is a proteolysis-targeting chimera (PROTAC) that induces selective degradation of BRD4 in cellular assays. Supplied as a solid research compound for in vitro use only; not for human or clinical use.

  • Targets BRD4 in cellular assays
  • Cas number: 2417370-42-2
  • Molecular formula: C59H71F2N9O15S4
  • Molecular weight: 1312.50 g/mol
  • Purity: 98.2%
  • Storage: powder at -20°C; in solvent: -80°C for 6 months, -20°C for 1 month
  • Available in mg-scale quantities suitable for research use

ENCOMPASS_PREFERRED
8

eMolecules​ Medchem Express / N-Arachidonyl maleimide / 10mg / 532149999 / HY-136562 / / 876305-42-9 / MFCD11521506 / 369.549 / C24H35NO2

Medchem Express / N-Arachidonyl maleimide / 10mg / 532149999 / HY-136562 / / 876305-42-9 / MFCD11521506 / 369.549 / C24H35NO2

ENCOMPASS_PREFERRED
9

eMolecules​ Pharmablock / tert-butyl N-[[1-(aminomethyl)cyclopropyl]methyl]carbamate / 25mg / 716543992 / PBU9128 / 0.000 / 1147109-42-9 / MFCD24212994 / 200.282 / C10H20N2O2

Pharmablock / tert-butyl N-[[1-(aminomethyl)cyclopropyl]methyl]carbamate / 25mg / 716543992 / PBU9128 / 0.000 / 1147109-42-9 / MFCD24212994 / 200.282 / C10H20N2O2

ENCOMPASS_PREFERRED
10

Medchemexpress LLC 1-(5Z,8Z,11Z,14Z)-5,8,11,14-eicosatetraen-1-yl-1H-pyrrole-2,5-dione | 876305-42-9 | MFCD11521506 | 98.3% | 369.54 | C24H35NO2 | 5 MG
SDP

N-Arachidonyl maleimide is an irreversible inhibitor of monoacylglycerol lipase (MAGL) used in research to modulate endocannabinoid signaling by increasing 2-arachidonyl glycerol (2-AG) levels. It inhibits MAGL with an IC50 of 140 nM and has been characterized for preventing cerebellar membrane-mediated degradation of 2-AG. The compound is supplied in solid and solution formats for biochemical and cellular studies.

  • Irreversible MAGL inhibitor with reported IC50 of 140 nM.
  • Modulates 2-AG levels by inhibiting enzymatic degradation.
  • High reported purity (≈98.3%), suitable for research applications.
  • Available in multiple pack sizes and a pre-made solution for experimental flexibility.
  • Molecular formula C24H35NO2; molecular weight 369.54 g·mol⁻1.
  • Commonly used in biochemical assays to study endocannabinoid metabolism.

ENCOMPASS_PREFERRED
11

Medchemexpress LLC Carbonic anhydrase 9 (recombinant protein) | 97.0% | 20 UG
SDP

Recombinant canine Carbonic Anhydrase 9 (CA9/CA-IX) produced in HEK293 cells with a C-terminal His tag. Supplied as a purified research reagent with reported purity of 97.0% and an approximate molecular weight of 42-55 kDa; pack size noted as 20 μg from the supplier SKU. Intended for antibody characterization, binding studies, and immunoassay development.

ENCOMPASS_PREFERRED