Quinolines and derivatives
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Filtered Search Results
TARGETMOL CHEMICALS INC LIQUIRITIGENIN 25MG
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Also available in 5 mg 10 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Liquiritigenin (4'7-Dihydroxyflavanone) a flavonoid aglycone from licorice is a highly selective estrogen receptor (beta) (ER(beta)) agonist. purity: 99%
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Medchemexpress LLC Azido-PEG7-amine | 1333154-77-0 | MFCD13185016 | >98.0% | 394.46 g/mol | C16H34N4O7 | 50 MG
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Azido-PEG7-amine is a bifunctional polyethylene glycol (PEG) linker bearing an azide and a primary amine terminus. It is used as a click-chemistry building block and as a linker in antibody-drug conjugate (ADC) and PROTAC synthesis.
- Bifunctional azide and primary amine termini suitable for conjugation.
- PEG7 spacer provides a short, flexible linker (seven ethylene glycol units).
- Compatible with copper-catalyzed azide-alkyne cycloaddition and strain-promoted click reactions.
- High reported purity, typically greater than 98%.
- Supplied in small laboratory pack sizes for research use.
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Medchemexpress LLC Benzyl-PEG5-amine | 86770-77-6 | MFCD28976656 | 98.0% | C17H29NO5 | 100 MG
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Benzyl-PEG5-amine is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. PROTACs are compounds characterized by two distinct ligands joined by a linker, where one ligand binds to an E3 ubiquitin ligase and the other to a target protein. This design enables PROTACs to utilize the intracellular ubiquitin-proteasome system to achieve the selective degradation of specific target proteins.
- Functions as a PROTAC linker.
- Supports the synthesis of PROTACs.
- Engages the ubiquitin-proteasome system for protein degradation.
- Enables selective degradation of target proteins.
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Medchemexpress LLC Dibenzocyclooctyne-amine | 1255942-06-3 | MFCD22380759 | 99.1% | 276.34 | C18H16N2O | 1 G
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DBCO-amine is a dibenzocyclooctyne-functionalized amine reagent used for copper-free click chemistry (strain-promoted alkyne-azide cycloaddition, SPAAC). It is supplied at high purity for bioconjugation and linker synthesis, and is suitable for labeling azide-bearing biomolecules.
- Enables copper-free SPAAC bioconjugation with azide groups
- High purity suitable for synthetic and bioconjugation workflows
- Available in multiple pack sizes, including 1 g for scale-up
- Used for ADC linker synthesis and labeling applications
- Soluble in common organic solvents such as DMSO
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Medchemexpress LLC Amino-PEG8-amine | 82209-36-7 | 98.0% | 500 MG
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Amino-PEG8-amine is a PEG-based (8 units) PROTAC linker used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Appears as liquid
- Color is colorless to light yellow
- Molecular weight: 412.52
- Molecular formula: C18H40N2O8
- CAS number: 82209-36-7
- Purity: 98.0%
- Store at 4°C, protected from light
- In solvent, store at -80°C for 6 months or -20°C for 1 month (protected from light)
- Soluble in DMSO at 100 mg/mL
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Medchemexpress LLC Azido-PEG10-amine | 912849-73-1 | 97.0% | C22H46N4O10 | 50 MG
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Azido-PEG10-amine is a PEG-based PROTAC linker used in the synthesis of PROTACs. It is also a click chemistry reagent containing an Azide group, which can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, it can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent
- Contains an Azide group
- Participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions
- Can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
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eMolecules 58794-09-5 | 7-Bromoisoquinoline | Ambeed | MFCD07368661 | 208.058 | C9H6BrN | 97.000 | Brc1ccc2ccncc2c1 | 100g | 525052809
7-Bromoisoquinoline | Ambeed | 58794-09-5 | MFCD07368661 | 208.058 | C9H6BrN | 97.000 | Brc1ccc2ccncc2c1 | 100g | 525052809
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eMolecules 5622-36-6 | methyl 2-(quinolin-6-yl)acetate | Pharmablock | MFCD04038669 | 201.225 | C12H11NO2 | 97.000 | COC(=O)Cc1ccc2ncccc2c1 | 2.5g | 686950173
methyl 2-(quinolin-6-yl)acetate | Pharmablock | 5622-36-6 | MFCD04038669 | 201.225 | C12H11NO2 | 97.000 | COC(=O)Cc1ccc2ncccc2c1 | 2.5g | 686950173
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eMolecules 58794-09-5 | 7-BROMOISOQUINOLINE | AstaTech | MFCD07368661 | 208.058 | C9H6BrN | 97.000 | Brc1ccc2ccncc2c1 | 25g | 296372928
7-BROMOISOQUINOLINE | AstaTech | 58794-09-5 | MFCD07368661 | 208.058 | C9H6BrN | 97.000 | Brc1ccc2ccncc2c1 | 25g | 296372928
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eMolecules 58794-09-5 | 7-bromoisoquinoline | AA Blocks LLC | MFCD07368661 | 208.058 | C9H6BrN | 0.000 | Brc1ccc2ccncc2c1 | 1g | 410166200
7-bromoisoquinoline | AA Blocks LLC | 58794-09-5 | MFCD07368661 | 208.058 | C9H6BrN | 0.000 | Brc1ccc2ccncc2c1 | 1g | 410166200
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Medchemexpress LLC Amine-PEG3-lys(PEG3-N3)-PEG3-N3 | 2244602-35-3 | 98.0% | 750.84 g/mol | C30H58N10O12 | 100 MG
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Amine-PEG3-Lys(PEG3-N3)-PEG3-N3 is a branched polyethylene glycol (PEG) linker designed for use in the synthesis of antibody-drug conjugates (ADCs). It features an amine terminus and multiple PEG3 spacers terminated with azide (N3) groups to enable orthogonal conjugation strategies.
- Branched PEG linker with amine and azide functional groups.
- Designed for ADC synthesis and bioconjugation.
- Multiple PEG3 spacers increase solubility and flexibility.
- Enables orthogonal conjugation via amine and azide chemistries.
- Typical reported purity 98.0%.
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Medchemexpress LLC Azido-PEG9-amine | 1207714-69-9 | MFCD30723241 | 98.5% | 482.57 g/mol | C20H42N4O9 | 100 MG
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Azido-PEG9-amine is an azide-terminated nine-unit polyethylene glycol (PEG) linker with a terminal primary amine used for bioconjugation and linker design. It is suitable for click chemistry and linker-based constructs, providing hydrophilic spacing between functional groups.
- Azide-terminated PEG linker compatible with CuAAC and SPAAC click reactions.
- Contains a primary amine for orthogonal functionalization.
- Nine ethylene glycol units provide hydrophilicity and spacing for conjugates.
- Reported high purity supports conjugation and analytical workflows.
- Available in small research-scale quantities for method development.
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Medchemexpress LLC Azido-PEG23-amine | 2172677-19-7 | 99.93% | C48H98N4O23 | 50 MG
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Azido-PEG23-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It functions as a click chemistry reagent, possessing an azide group that enables various cycloaddition reactions.
- PEG-based PROTAC linker
- Click chemistry reagent
- Contains an azide group
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) reaction with alkyne groups
- Participates in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups
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Medchemexpress LLC m-PEG8-amine | 869718-81-0 | MFCD13184961 | ≥98.0% | 383.48 g·mol⁻¹ | C17H37NO8 | 100 MG
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m-PEG8-amine is an 8-unit monomethoxy polyethylene glycol (PEG) bearing a terminal primary amine used as a cleavable spacer/linker in antibody-drug conjugates and for general bioconjugation. It is supplied as a powder and is typically handled and stored according to the supplier's safety documentation.
- Chemical name: m-PEG8-amine
- Cas number: 869718-81-0
- Purity: ≥98.0%
- Molecular formula: C17H37NO8
- Molecular weight: 383.48 g·mol⁻¹
- Typical solubility: soluble in DMSO
- Available pack sizes: 50 MG, 100 MG, 500 MG, 1 G, 5 G, 10 G, 50 G
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Medchemexpress LLC Trifluoperazine dihydrochloride | 440-17-5 | 99.9% | 50 MG
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Trifluoperazine dihydrochloride is an antipsychotic agent that functions by blocking central dopamine receptors. It also acts as a potent α1-adrenergic receptor antagonist and a NUPR1 inhibitor, demonstrating anticancer activity. Furthermore, it is a calmodulin inhibitor and inhibits P-glycoprotein. This compound is utilized in research for schizophrenia and acts as a reversible inhibitor of influenza virus morphogenesis by interfering with cellular CaM and/or CaM-dependent functions.
- Blocks central dopamine receptors
- Potent α1-adrenergic receptor antagonist
- Potent NUPR1 inhibitor with anticancer activity
- Calmodulin inhibitor
- Inhibits P-glycoprotein
- Utilized in research for schizophrenia
- Acts as a reversible inhibitor of influenza virus morphogenesis
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