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Filtered Search Results
Medchemexpress LLC Benzyl-PEG2-amine | 1268135-96-1 | C11H17NO2 | 1 G
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Benzyl-PEG2-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Connects ligands for E3 ubiquitin ligase and target proteins
- Utilizes the ubiquitin-proteasome system
- Selectively degrades target proteins
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Medchemexpress LLC 6-Aminoquinoline | 580-15-4 | 144.17 | 10 G
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6-Aminoquinoline is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
- Can be used as a biological material or organic compound
- Suitable for life science related research
- Appears as a solid
- Ranges in color from light yellow to brown
- Soluble in DMSO at concentrations of 200 mg/mL or greater
- Store at 4°C, protected from light
- When in solvent, store at -80°C for 6 months or -20°C for 1 month, protected from light
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Medchemexpress LLC Icg-amine | 1686147-55-6 | 98.3% | 829.14 g/mol | C51H64N4O4S | 5 MG
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ICG-amine is a near-infrared tricarbocyanine fluorescent probe that reacts with amino acid residues without requiring condensing agents. Supplied as a green to dark green solid, it is used for in vivo and animal imaging applications, including cancer imaging and studies of metabolism and metastasis.
- Binds amino acid residues without condensing agents.
- Near-infrared fluorescence suitable for deep tissue imaging.
- High purity (98.34%) for research use.
- Soluble in DMSO and water with heat and sonication; compatible with common in vivo formulations.
- Provided as a solid with a defined molecular weight and molecular formula for characterization.
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Medchemexpress LLC Amino-PEG7-amine | 332941-25-0 | 99.3% | C16H36N2O7 | 100 MG
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Amino-PEG7-amine is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. This mechanism allows PROTACs to exploit the intracellular ubiquitin-proteasome system for the selective degradation of target proteins. It is intended for research use only.
- Utilized in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- Intended for research use only
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Medchemexpress LLC DBCO-amine | 1255942-06-3 | 99.1% | 276.34 g·mol-1 | C18H16N2O | 25 MG
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DBCO-amine is a dibenzocyclooctyne-containing amine reagent used for strain-promoted alkyne-azide cycloaddition (SPAAC) click chemistry. It is used as a small linker for bioconjugation and the synthesis of antibody-drug conjugates, and is typically handled and stored under anhydrous conditions and in organic solvent solutions for formulation.
- Enables strain-promoted alkyne-azide cycloaddition (SPAAC) bioconjugation.
- High purity suitable for synthetic and bioconjugation applications.
- Minimal spacer length reduces steric hindrance in conjugates.
- Compatible with common coupling chemistries for linker installation.
- Soluble in DMSO for straightforward formulation and handling.
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Medchemexpress LLC Isoquinolin-4-amine | 23687-25-4 | 144.17 | 10 G
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Isoquinolin-4-amine is a biochemical reagent used as a biological material or organic compound for life science-related research. It is intended for research use only.
- Can be used as a biological material
- Can be used as an organic compound
- Suitable for life science-related research
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Advanced Chemblocks Inc 5-Bromo-isoquinolin-8-ylamine; 25G; 95%
Chemical Name: 5-Bromo-isoquinolin-8-ylamine CAS: 90721-35-0 MW: 223.07 MDL Number: MFCD09261047 Category: isoquinoline Synonym: 5-Bromo-isoquinolin-8-ylamine
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Selleck Chemical LLC JNK-IN-8 S4901-1g
JNK-IN-8 (JNK Inhibitor XVI) is the first irreversible JNK inhibitor for JNK1 JNK2 and JNK3 with IC50 of 4 7 nM 18 7 nM and 1 nM 10-fold selectivity against MNK2 Fms and no inhibition to c-Kit Met PDGFR in A375 cell line
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Medchemexpress LLC Anhydrous sodium dihydrogen phosphate, for HPLC | 7558-80-7 | 99.9% | 10 G
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Anhydrous sodium dihydrogen phosphate, for HPLC is widely used in molecular biology, biochemistry and chromatography. It can serve as a pH buffer and can be used as an excipient, such as a buffer or chelating agent, in pharmaceutical processes. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve stability, solubility, and processability, and also affect the absorption, distribution, metabolism, and elimination processes of co-administered drugs.
- Widely used in molecular biology, biochemistry, and chromatography
- Can serve as a pH buffer
- Used as an excipient in pharmaceutical preparations
- Improves stability, solubility, and processability of pharmaceuticals
- Affects ADME processes of co-administered drugs
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Medchemexpress LLC 5-Bromoisoquinoline | 34784-04-8 | 208.058 | 250 G
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5-Bromoisoquinoline is a biochemical reagent that can be used as a biological material or organic compound for life science related research. It is also a synthetic intermediate useful for pharmaceutical synthesis.
- Biochemical reagent
- Used as a biological material or organic compound
- Useful for life science related research
- Synthetic intermediate for pharmaceutical synthesis
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Medchemexpress LLC Quin-C7 | 871100-12-8 | 99.8% | 431.48 | C25H25N3O4 | 1 ML
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Quin-C7 is an orally active antagonist of the formyl peptide receptor FPR2/ALX with reported anti-inflammatory activity in preclinical models. It has been used to ameliorate DSS-induced colitis in mice and is supplied for research use as either a 10 mM solution in DMSO (1 mL) or as a solid powder.
- Orally active FPR2/ALX antagonist with anti-inflammatory activity.
- Demonstrated efficacy in DSS-induced colitis mouse models.
- Available as a 10 mM solution in DMSO (1 mL) or as a solid form.
- High purity solid form (99.76%).
- Molecular formula C25H25N3O4; molecular weight 431.48; CAS 871100-12-8.
- Storage: powder at -20°C (up to 3 years) or 4°C (up to 2 years); solution at -80°C (up to 6 months) or -20°C (up to 1 month).
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Medchemexpress LLC 8-Aminoquinoline | 578-66-5 | MFCD00006809 | 144.17 | 5 G
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8-Aminoquinoline is a biochemical reagent. It can be utilized as a biological material or an organic compound for various life science-related research applications.
- Biochemical reagent
- Suitable for life science related research
- Can be used as a biological material
- Can be used as an organic compound
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Medchemexpress LLC L-Cystathionine dihydrochloride | 61125-50-6 | 295.18 | 5 MG
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L-Cystathionine dihydrochloride is a nonprotein thioether and a key amino acid involved in the metabolic state of sulfur-containing amino acids. It has been shown to protect against Homocysteine-induced mitochondria-dependent apoptosis of vascular endothelial cells (HUVECs). This suggests an important role for L-Cystathionine in cardiovascular protection.
- Key amino acid associated with the metabolic state of sulfur-containing amino acids
- Protects against Homocysteine-induced mitochondria-dependent apoptosis of vascular endothelial cells (HUVECs)
- Plays an important role in cardiovascular protection
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Medchemexpress LLC L-Cystathionine dihydrochloride | 61125-50-6 | MFCD00036665 | 99.9% | 295.18 | 25 MG
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L-Cystathionine dihydrochloride is an analytical standard intended for research and analytical applications. This nonprotein thioether is a key amino acid associated with the metabolic state of sulfur-containing amino acids. It protects against Homocysteine-induced mitochondria-dependent apoptosis of vascular endothelial cells (HUVECs) and plays an important role in cardiovascular protection.
- Analytical standard grade for research and analytical applications.
- Nonprotein thioether and key amino acid.
- Protects against Homocysteine-induced mitochondria-dependent apoptosis of vascular endothelial cells (HUVECs).
- Plays an important role in cardiovascular protection.
- Commonly used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
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Medchemexpress LLC Amifostine thiol dihydrochloride | 14653-77-1 | MFCD00460339 | >98.0% | 207.16 g·mol⁻¹ | C5H16Cl2N2S | 1 ML
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Amifostine thiol dihydrochloride (WR-1065 dihydrochloride) is the active thiol metabolite of amifostine used as a research reagent for radioprotection and cytoprotection. It is reported to protect normal tissues from the toxic effects of certain chemotherapeutic and radiotherapeutic agents and to activate p53 via a JNK-dependent signaling pathway, making it useful in studies of apoptosis, DNA damage response, and MDM2-p53 signaling.
- Cytoprotective and radioprotective research reagent suitable for cellular assays.
- Reported to activate p53 through a JNK-dependent signaling pathway.
- Provided as a ready-to-use 10 mM solution (1 mL) for experimental convenience.
- Also available in solid formats for formulation or analytical applications.
- Useful for apoptosis, DNA damage response, and MDM2-p53 pathway studies.
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