Quinolines and derivatives

Aromatic organic heterocyclic compounds that contain a benzene ring fused with a six-membered ring that contains one nitrogen atom and five carbon atoms. Includes compounds that are derived from quinolines.

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3,796 – 3,810 of 5,528 results

3,796

Medchemexpress LLC Bromocriptine mesylate | 22260-51-1 | MFCD00069218 | 100.0% | 750.70 g/mol | C33H44BrN5O8S | 5 MG

Bromocriptine mesylate is the methanesulfonate salt of bromocriptine, a semisynthetic ergot-derived dopamine D2/D3 receptor agonist used in research. It shows high affinity for D2 receptors (pKi ≈ 8.05) and is provided as both a solid and solution format for laboratory and analytical applications.

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3,797

Medchemexpress LLC Ruboxistaurin mesylate | 192050-59-2 | MFCD09970504 | 99.9% | 564.65 | C29H32N4O6S | 5 MG

Ruboxistaurin mesylate is an orally active, ATP-competitive, and selective protein kinase C beta (PKCβ) inhibitor used in preclinical research on diabetic complications, retinal/eye disorders, and cardiovascular disease. It is supplied as a solid with high reported purity and is soluble in DMSO for in vitro applications.

Selective PKCβ inhibitor with low-nanomolar potency.
Orally active small molecule suitable for in vitro and in vivo studies.
High reported purity (~99.9%) for research applications.
Solid form, orange to red color, easy handling and storage.
Soluble in DMSO at 50 MG/ML (88.55 mM); ultrasonic assistance may be required.
Storage guidance: 4°C sealed; in solvent: -80°C (6 months), -20°C (1 month).

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3,798

Medchemexpress LLC Danofloxacin mesylate | 119478-55-6 | MFCD00673687 | 99.9% | 100 MG

Danofloxacin mesylate (CP 76136-27) is a fluoroquinolone used as a veterinary drug. It exhibits broad-spectrum bactericidal activity primarily by inhibiting bacterial DNA gyrase and also functions as a substrate for ATP-dependent efflux transporters such as P-gp and MRP2.

Used as a veterinary drug
Broad-spectrum bactericidal activity
Inhibits bacterial DNA gyrase
Substrate for ATP-dependent efflux transporters (P-gp and MRP2)
Targets P-glycoprotein and bacterial components
Involves membrane transporter/ion channel and anti-infection mechanisms
Effective against bovine bacterial respiratory pathogens
Demonstrates asymmetric transport across Caco-2 cells

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3,799

Medchemexpress LLC Danofloxacin mesylate | 119478-55-6 | 99.9% | 50 MG

Danofloxacin mesylate is a fluoroquinolone used as a veterinary drug. It exhibits a broad spectrum of bactericidal activity, primarily by inhibiting the DNA cycloenzyme of bacteria. Additionally, it acts as a substrate for ATP-dependent efflux transporters (P-gp and MRP2).

Used as a veterinary drug
Exhibits a broad spectrum of bactericidal activity
Primarily inhibits bacterial DNA cycloenzyme
Acts as a substrate for ATP-dependent efflux transporters (P-gp and MRP2)

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3,800

Medchemexpress LLC Ergi-USU-6 mesylate | 2756327-67-8 | 95.0% | C14H18N4O4S | 10MG

ERGi-USU-6 mesylate is a research-grade small-molecule inhibitor of ERG and RIOK2 with reported cellular potency (IC50 ≈ 0.13-0.17 μM in VCaP cells). The methanesulfonate salt is supplied as a solid with a reported purity of 95% and is intended for in vitro and preclinical research use.

Inhibits ERG and RIOK2 with submicromolar cellular potency.
Demonstrates antiproliferative activity in ERG-positive prostate cancer models.
Supplied as a mesylate salt for improved handling and stability.
High reported purity suitable for biochemical and cell-based assays.
Solid form with defined cold-storage recommendations for sample integrity.

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3,801

Medchemexpress LLC Bromocriptine mesylate | 22260-51-1 | 99.90% | 200 MG

Bromocriptine mesylate is a potent dopamine D2/D3 receptor agonist, binding to the D2 dopamine receptor with a pKi of 8.05. It is permeable to the blood-brain barrier. This compound also acts as a strong inhibitor of brain nitric oxide synthase (NOS) with an IC50 of 10±2 μM for purified neuronal NOS, and poorly inhibits inducible macrophage NOS (IC50>100 μM). Additionally, it is a potent inhibitor of CYP3A4, with a calculated IC50 value of 1.69 μM.

Potent dopamine D2/D3 receptor agonist
Permeable to the blood-brain barrier
Strong inhibitor of brain nitric oxide synthase (NOS)
Potent inhibitor of CYP3A4
Shows anti-immobility action in mice (in FST and TST)
Potentiates the anti-immobility action of MPE
Decreases static mechanical allodynia (SMA) score in rats

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3,802

Medchemexpress LLC Deferoxamine (mesylate) | 138-14-7 | 99.8% | 20 MG

Deferoxamine mesylate is an iron chelator that binds to Fe(III) and other metal cations. It is widely used to reduce iron accumulation and deposition in tissues. This compound upregulates HIF-1α levels with good antioxidant activity, shows anti-proliferative activity, and can induce apoptosis and autophagy in cancer cells. It is applicable in studies of diabetes, neurodegenerative diseases, anti-cancer research, and anti-COVID-19 research.

Binds to Fe(III) and other metal cations
Reduces iron accumulation and deposition in tissues
Upregulates HIF-1α levels
Exhibits good antioxidant activity
Shows anti-proliferative activity
Induces apoptosis and autophagy in cancer cells
Applicable in studies related to diabetes, neurodegenerative diseases, anti-cancer research, and anti-COVID-19 research

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3,803

Medchemexpress LLC Deferoxamine mesylate (Standard) | 138-14-7 | 99.47% | 100 MG

Deferoxamine mesylate (Standard) is the analytical standard for Deferoxamine mesylate, intended for research and analytical applications. It is an iron chelator, binding to Fe(III) and other metal cations, and is widely used to reduce iron accumulation and deposition in tissues. It also upregulates HIF-1α levels with good antioxidant activity, shows anti-proliferative activity, and can induce apoptosis and autophagy in cancer cells. This compound can be used in studies related to diabetes, neurodegenerative diseases, anti-cancer research, and anti-COVID-19 research.

The compound is an analytical standard, serving as a reference standard for assays.
Commonly employed in qualitative, quantitative, and methodological research experiments such as HPLC, GC, and MS.

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3,804

TARGETMOL CHEMICALS INC OBATOCLAX MESYLATE 25MG

Also available in 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Obatoclax Mesylate (GX15-070) is a Bcl-2 antagonist (Ki 0.22 uM) and can induce apoptosis with up-regulation of Bim induced cytochrome c release and activation of caspase-3. purity: 99%

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3,805

Medchemexpress LLC Firmonertinib mesylate | 2130958-55-1 | 100.0% | 664.70 | 50 MG

Firmonertinib mesylate is an orally active, mutant-selective, and blood-brain barrier penetrant EGFR inhibitor. It inhibits EGFR active mutations as well as the T790M acquired resistant mutation. It has potential for the research of cancer diseases, especially advanced non-small cell lung cancer (NSCLC) with EGFR ex20ins mutation.

Orally active
Mutant-selective
Blood-brain barrier penetrant EGFR inhibitor
Inhibits EGFR active mutations and T790M acquired resistant mutation
Potential for research of cancer diseases, especially advanced NSCLC with EGFR ex20ins mutation

Pricing & Availability

3,806

Medchemexpress LLC Dihydroergocristine mesylate | 24730-10-7 | MFCD00153792 | ≥98.0% | 707.84 | C36H45N5O8S | 10 MG

Dihydroergocristine mesylate is a research reagent reported to act as a γ-secretase inhibitor; it reduces production of amyloid-β peptides and binds directly to γ-secretase and nicastrin. It is supplied as the mesylate salt for use in neuroscience and Alzheimer's disease research.

Acts as a γ-secretase inhibitor.
Reduces production of amyloid-β peptides.
Binds directly to γ-secretase and nicastrin.
Supplied as the mesylate salt.
Available in small research quantities suitable for analytical or in-vitro studies.

Pricing & Availability

3,807

Sigma Aldrich Fine Chemicals Biosciences Methysergide maleate salt solid | 129-49-7 | MFCD00083185 | 2MG

Methysergide maleate salt solid | Mol Wt: 469.53 | 129-49-7 | MFCD00083185 | 2MG

Pricing & Availability

3,808

eMolecules 383907-43-5 | Medchem Express | NSC 663284 | 2mg | 446254896 | HY-100034 | MFCD08276924 | 321.76 | C15H16ClN3O3

Ambeed | 4-Bromo-25-dichlorobenzoic acid | 250mg | 525031901 | A128739 | 885532-41-2 | MFCD08444534 | 269.900 | C7H3BrCl2O2

If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool

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3,809

Aobchem 2 2-Difluoroethylmethane sulfonate | ≥95% | CAS 163035-65-2 | C3H6F2O3S | 5g

2 2-Difluoroethylmethane sulfonate | ≥95% | CAS 163035-65-2 | C3H6F2O3S | 5g

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3,810

Medchemexpress LLC Ruboxistaurin mesylate | 192050-59-2 | 99.9% | 564.65 g/mol | C29H32N4O6S | 50 MG

Ruboxistaurin mesylate is an orally active, selective, ATP-competitive protein kinase C beta (PKCβ) inhibitor used in preclinical research on diabetic complications, retinal disorders, and cardiovascular conditions. Supplied as the mesylate salt, it is an orange-to-red solid with molecular formula C29H32N4O6S and molecular weight 564.65 g/mol.

Selective PKCβ inhibition with low nanomolar potency (IC50 ~4.7-5.9 nM).
Mesylate salt form for improved stability and handling.
High purity (99.87%) suitable for research applications.
Orange-to-red solid, convenient for solid-state storage.
Molecular formula C29H32N4O6S and molecular weight 564.65 g/mol.

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Quinolines and derivatives

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Medchemexpress LLC Bromocriptine mesylate | 22260-51-1 | MFCD00069218 | 100.0% | 750.70 g/mol | C33H44BrN5O8S | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Ruboxistaurin mesylate | 192050-59-2 | MFCD09970504 | 99.9% | 564.65 | C29H32N4O6S | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Danofloxacin mesylate | 119478-55-6 | MFCD00673687 | 99.9% | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Danofloxacin mesylate | 119478-55-6 | 99.9% | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Ergi-USU-6 mesylate | 2756327-67-8 | 95.0% | C14H18N4O4S | 10MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Bromocriptine mesylate | 22260-51-1 | 99.90% | 200 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Deferoxamine (mesylate) | 138-14-7 | 99.8% | 20 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Deferoxamine mesylate (Standard) | 138-14-7 | 99.47% | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Firmonertinib mesylate | 2130958-55-1 | 100.0% | 664.70 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Dihydroergocristine mesylate | 24730-10-7 | MFCD00153792 | ≥98.0% | 707.84 | C36H45N5O8S | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Ruboxistaurin mesylate | 192050-59-2 | 99.9% | 564.65 g/mol | C29H32N4O6S | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More