Quinolines and derivatives
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Filtered Search Results
Apexbio Technology LLC CP 339818 hydrochloride 10mg
CP 339818 hydrochloride (CAS 478341-55-8) is a small-molecule antagonist targeting the Kv1 3 potassium channel It is designed to selectively inhibit Kv1 3-mediated ion conductance thereby modulating T-cell activation CP 339818 hydrochloride exerts its biological activity primarily through stabilization of the Kv1 3 channel s C-type inactivation state In in vitro studies CP 339818 hydrochloride demonstrates potent inhibition of Kv1 3 channels with an IC50 value of approximately 200 nM Based on these pharmacological properties CP 339818 hydrochloride holds research potential in the investigation of immune modulation mechanisms relevant to autoimmune and inflammatory disorders
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Medchemexpress LLC Quinine sulfate | 549-56-4 | 97.0% | 100 MG
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Quinine sulfate from MedChemExpress is an antiarrhythmic agent. It acts as a potent, orally active, selective cytochrome P450db inhibitor and a K+ channel blocker with an IC50 of 19.9 μM. It is also used for malaria research.
- Acts as an antiarrhythmic agent.
- Functions as a potent, orally active, selective cytochrome P450db inhibitor.
- Blocks K+ channels with an IC50 of 19.9 μM.
- Suitable for malaria research.
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Medchemexpress LLC Quinidine methiodide | 42982-87-6 | C21H27IN2O2 | 100 MG
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Quinidine methiodide is a metabolite of Quinidine, an established antiarrhythmic agent. This compound is intended for research use only and is not sold to patients.
- Metabolite of quinidine
- Antiarrhythmic agent
- For research purposes
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Medchemexpress LLC Mefloquine | 53230-10-7 | 99.96% | 378.31 | 50 MG
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Mefloquine (Standard) is the analytical standard of Mefloquine, intended for research and analytical applications. It is an orally active and potent quinoline antimalarial agent and an anti-SARS-CoV-2 entry inhibitor. Mefloquine also acts as a K+ channel (KvQT1/minK) antagonist with an IC50 of approximately 1 μM. It can be utilized for malaria, systemic lupus erythematosus, and cancer research.
- Analytical standard of Mefloquine.
- Intended for research and analytical applications.
- Orally active and potent quinoline antimalarial agent.
- Anti-SARS-CoV-2 entry inhibitor.
- K+ channel (KvQT1/minK) antagonist with an IC50 of ~1 μM.
- Applicable for malaria, systemic lupus erythematosus, and cancer research.
- Used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
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Medchemexpress LLC Mefloquine (Standard) | 53230-10-7 | MFCD00869324 | 378.31 | 100 MG
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Mefloquine (Standard) is the analytical standard of Mefloquine, intended for research and analytical applications. It is an orally active and potent quinoline antimalarial agent and an anti-SARS-CoV-2 entry inhibitor. Mefloquine is also a K+ channel (KvQT1/minK) antagonist with an IC50 of ~1 μM. This analytical standard grade compound is commonly used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
- Orally active and potent quinoline antimalarial agent.
- Anti-SARS-CoV-2 entry inhibitor.
- K+ channel (KvQT1/minK) antagonist.
- Used for malaria, systemic lupus erythematosus, and cancer research.
- Analytical standard grade for qualitative, quantitative, and methodological research experiments.
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Medchemexpress LLC Cinchonine | 118-10-5 | MFCD00064372 | 99.7% | 294.39 g/mol | C19H22N2O | 50g
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Cinchonine is a natural compound present in Cinchona bark with antimalarial antitumor anti-inflammatory anti platelet-aggregation and anti-obesity properties Cinchonine inhibits cells proliferation and autophagy and induces apoptosis through activation of Caspase-3 Cinchonine activates endoplasmic reticulum stress-induced apoptosis in human liver cancer cells[1]
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Selleck Chemical LLC Hydroquinine S5114-25mg
Hydroquinine (Dihydroquinine) also known as dihydroquinine is an organic compound and as a cinchona alkaloid closely related to quinine
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Selleck Chemical LLC Hydroquinidine S4658-100mg
Hydroquinidine (Dihydroquinidine Hydroconchinine Hydroconquinine Dihydroquinine) is an antiarrhythmic agent
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Medchemexpress LLC Imiquimod hydrochloride | 99011-78-6 | 99.8% | 100 MG
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Imiquimod hydrochloride (R 837 hydrochloride) is an immune response modifier and a selective toll-like receptor 7 (TLR7) agonist. It exhibits antiviral and antitumor effects in vivo and can be used for the research of external genital, perianal warts, cancer, and COVID-19.
- Exhibits antiviral effects in vivo
- Exhibits antitumor effects in vivo
- Selective TLR7 agonist
- Used in research for external genital, perianal warts, cancer, and COVID-19
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Aobchem 8-Methyl-5-quinolinecarboxylic acid | ≥95% | CAS 74316-52-2 | C11H9NO2 | 5g
8-Methyl-5-quinolinecarboxylic acid | ≥95% | CAS 74316-52-2 | C11H9NO2 | 5g
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Medchemexpress LLC Adagrasib | 2326521-71-3 | >99.9% | 200 MG
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Adagrasib (MRTX849) is a potent, orally-available, and mutation-selective covalent inhibitor of KRAS G12C with potential antineoplastic activity. It covalently binds to KRAS G12C at the cysteine at residue 12, locking the protein in its inactive GDP-bound conformation and inhibiting KRAS-dependent signal transduction.
- Potent and orally-available.
- Mutation-selective covalent inhibitor of KRAS G12C.
- Potential antineoplastic activity.
- Inhibits KRAS-dependent signal transduction.
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Medchemexpress LLC Ethyl indole-2-carboxylate | 3770-50-1 | 99.7% | 189.21 | 50 G
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2-Carbethoxyindole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
- For research use only. We do not sell to patients.
- An indole derivative.
- Inhibits benzodiazepine receptor with IC50= 2.2 mM.
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eMolecules 345909-35-5 | 4-Hydroxyquinoline-2-carboxylic acid hydrate | Apollo Scientific | MFCD00149476 | 207.185 | C10H9NO4 | 95.000 | O.OC(=O)c1cc(O)c2ccccc2n1 | 1g | 562444254
4-Hydroxyquinoline-2-carboxylic acid hydrate | Apollo Scientific | 345909-35-5 | MFCD00149476 | 207.185 | C10H9NO4 | 95.000 | O.OC(=O)c1cc(O)c2ccccc2n1 | 1g | 562444254
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TARGETMOL CHEMICALS INC CP-466722 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. CP-466722 an effective and reversible ATM inhibitor does not inhibit ATR and PI3K or PIKK family members in cells. purity: 99%
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Medchemexpress LLC Fasiglifam (TAK-875) | 1000413-72-8 | MFCD18251445 | 99.0% | 524.63 | C29H32O7S | 200 MG
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Fasiglifam (TAK-875) is a potent, selective, orally bioavailable GPR40 (FFAR1) agonist used in research to study glucose-dependent insulin secretion and GPR40 pharmacology. The compound is supplied as a solid research reagent with documented potency and chemical characterization (formula C29H32O7S; MW 524.63 g/mol).
- Potent, selective GPR40 agonist with reported EC50 of 72 nM.
- Orally bioavailable pharmacology profile suitable for in vitro and in vivo studies.
- High purity (~99%) suitable for laboratory research.
- Available in multiple sizes including milligram and gram quantities.
- Chemical formula C29H32O7S and molecular weight 524.63 g/mol.
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