Quinolines and derivatives
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Filtered Search Results
Medchemexpress LLC IL-31 Cynomolgus H 2ug | 2ug
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IL-31 is a multifunctional cytokine that activates STAT3 through IL-31 heterodimeric receptors (IL31RA and OSMR) and may activate STAT1 and STAT5 IL-31 is known for its involvement in skin immunity where it regulates immune responses IL-31 Protein Cynomolgus (HEK293 His) is the recombinant cynomolgus-derived IL-31 protein expressed by HEK293 with C-His labeled tag
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Medchemexpress LLC DC-BPi-03 | 2758411-46-8 | C14H14N4O2S | 10 MM/1 ML
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DC-BPi-03 is a potent BPTF-BRD inhibitor with an IC50 of 698.3 nM and a Kd of 2.81 μM. It is for research use only and not sold to patients.
- Potent BPTF-BRD inhibitor
- IC50 of 698.3 nM
- Kd of 2.81 μM
- Solid appearance
- White to off-white color
- Purity of 99.77%
- For research use only
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Medchemexpress LLC Methyl 3,3-dimethoxypropionate | 7424-91-1 | MFCD00010650 | >98.0% | 148.16 g/mol | C6H12O4 | 500 G
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Methyl 3,3-dimethoxypropionate is an organic methyl ester used as a reagent and building block in organic synthesis and life-science research. It is provided as a high-purity material with documented physical data and recommended storage conditions to preserve stability.
- Used as a synthetic building block in organic chemistry.
- High purity (>98%) supports analytical and preparative work.
- Molecular weight 148.16 g/mol and formula C6H12O4 for stoichiometric calculations.
- Soluble in DMSO (10 mM) for solution-phase assays.
- Recommended storage at -20°C (long term) or 4°C (short term) as powder.
- Intended for research use only.
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Medchemexpress LLC 2,6-Dimethoxy-1,4-benzoquinone | 530-55-2 | 168.15 | 500 MG
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2,6-Dimethoxy-1,4-benzoquinone | 530-55-2 | 168.15 | 500 MG
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Medchemexpress LLC 3-[2-cyano-3-(trifluoromethyl)phenoxy]phenyl-4,4,4-trifluoro-1-butanesulfonate | 406205-74-1 | 98.6% | 453.36 g·mol⁻1 | C18H13F6NO4S | 50 MG
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BAY 59-3074 is a cannabinoid CB1/CB2 receptor partial agonist originally reported by Bayer. It has been characterized in vitro and in vivo for analgesic and antihyperalgesic effects and is used in research to probe cannabinoid receptor pharmacology.
- Selective CB1/CB2 receptor partial agonist (human CB1 Ki = 48.3 nM; human CB2 Ki = 45.5 nM).
- High purity: 98.6%.
- Chemical formula C18H13F6NO4S; molecular weight 453.36 g·mol⁻1.
- Solid, white to off-white physical form, suitable for laboratory handling.
- Documented in peer-reviewed literature and product datasheets for research use.
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Medchemexpress LLC Exendin-3/4 (59-86) Pedin-3/4 (59-86 | 1263874-37-8 | 98.2% | 3055.42 | 5 MG
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Exendin-3/4 (59-86) is a derivative of Exendin-4 peptide. Exendin-4 itself is a pure GLP-1 receptor agonist. Exendin-4 peptide derivatives are structurally derived from Exendin-4 and may be related to dual GLP-1/glucagon receptor agonists.
- Peptide derivative.
- Structurally derived from Exendin-4.
- May relate to dual GLP-1/glucagon receptor agonists.
- Potential medical use in treating disorders of the metabolic syndrome, including diabetes and obesity.
- May help with the reduction of excess food intake.
- Shows reduced activity on the GIP receptor, which may lower the risk of hypoglycemia.
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![Medchemexpress LLC 6-(2-(4-((4-fluorophenyl)phenylmethylidene)piperidin-1-yl)ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one | 93076-89-2 | MFCD00055114 | ≥98.0% | 459.58 g/mol | C27H26FN3OS | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000240435.png-250.jpg)
Medchemexpress LLC 6-(2-(4-((4-fluorophenyl)phenylmethylidene)piperidin-1-yl)ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one | 93076-89-2 | MFCD00055114 | ≥98.0% | 459.58 g/mol | C27H26FN3OS | 25 MG
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R 59-022 is a small-molecule research reagent that inhibits diacylglycerol kinase (DGK) and functions as a 5-HT receptor antagonist. It is used to modulate protein kinase C (PKC) activation and diacylglycerol-dependent signaling in biochemical and cell-based studies. Chemical identifiers include CAS 93076-89-2, formula C27H26FN3OS, and molecular weight ≈459.58 g/mol.
- Potent DGK inhibitor (reported IC50 ≈ 2.8 μM).
- Modulates PKC activation and diacylglycerol signaling.
- Used in platelet aggregation and cellular signaling studies.
- High reported purity (≥98%).
- Provided in small research quantities suitable for assay development.
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eMolecules 886362-75-0 | 4-Chloro-6,7-difluoro-quinoline-3-carbonitrile | Combi-Blocks | MFCD06796586 | 224.590 | C10H3ClF2N2 | 98.000 | Fc1cc2ncc(C#N)c(Cl)c2cc1F | 25g | 448004410
4-Chloro-6,7-difluoro-quinoline-3-carbonitrile | Combi-Blocks | 886362-75-0 | MFCD06796586 | 224.590 | C10H3ClF2N2 | 98.000 | Fc1cc2ncc(C#N)c(Cl)c2cc1F | 25g | 448004410
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Medchemexpress LLC SLF-amido-C2-COOH 5mg | 1092369-24-8 | 5MG
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SLF-amido-C2-COOH (PROTAC FKBP12-binding moiety 1) is a synthetic ligand for FKBP (SLF) SLF-amido-C2-COOH (PROTAC FKBP12-binding moiety 1) can be used in the synthesis of PROTACs[1
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Medchemexpress LLC Pomalidomide-amido-c5-peg2-c6-chlorine | 1835705-69-5 | 98.75% | 594.10 | 25 MG
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Pomalidomide-amido-C5-PEG2-C6-chlorine is a derivative of Pomalidomide. It is intended for research use only and is not sold to patients. The compound has a molecular weight of 594.10 and a chemical formula of C29H40ClN3O8. It appears as a white to off-white solid. This compound is cited in research related to the modular design of PROTACs for the degradation of oncogenic BCR-ABL.
- It is a derivative of Pomalidomide.
- It is used for research purposes only.
- It is a solid with a white to off-white appearance.
- It has been utilized in studies concerning PROTAC design for degrading oncogenic BCR-ABL.
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Medchemexpress LLC FX-06 1mg | 88650-17-3 | 1MG
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FX-06 (Fibrin-derived peptide B 15-42) is a fibrin Bbeta chain-derived peptide FX-06 binds to VE-cadherin and inhibits leukocyte transmigration and initiates VE-cadherin-mediated signaling FX-06 can be used in the research of ischemia/reperfusion injury Dengue shock syndrome (DSS)[1 [2 [4
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Medchemexpress LLC 2(1H)-Phthalazineacetamide, 4-(4-chlorophenyl)-N-(4-fluorophenyl)-1-oxo- | 684234-60-4 | 98.6% | 407.82 | 25 MG
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2(1H)-Phthalazineacetamide, 4-(4-chlorophenyl)-N-(4-fluorophenyl)-1-oxo- | 684234-60-4 | 98.6% | 407.82 | 25 MG
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Medchemexpress LLC PVD-06 | 3032975-48-4 | 98.3% | 1074.13 | 1 MG
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PVD-06 is a selective PROTAC PTPN2 degrader with a DC50 of 217 nM. It induces PTPN2 degradation via a VHL-, ubiquitin, and proteasome-dependent pathway. PVD-06 can promote T cell activation and amplify IFN-γ-mediated anticancer activity, making it suitable for investigating PTPN2 in diseases such as leukemia and melanoma.
- Selective PROTAC PTPN2 degrader
- Induces PTPN2 degradation via VHL-, ubiquitin, and proteasome-dependent pathway
- Promotes T cell activation
- Amplifies IFN-γ-mediated anticancer activity
- Composed of a PTPN2 ligand, a linker, and a VHL ligand
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Medchemexpress LLC 4,7,10,13,16-pentaoxanonadecane-1,19-diamine | 869308-34-9 | 97.5% | 308.41 g/mol | C14H32N2O5 | 25 MG
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4,7,10,13,16-pentaoxanonadecane-1,19-diamine is a polyethylene glycol (PEG)-based diamine linker provided for laboratory research and chemical synthesis. It is a colorless to light-yellow liquid (MW 308.41 g/mol, CAS 869308-34-9) whose two terminal primary amines and ether-rich backbone make it suitable as a bifunctional spacer in bioconjugation and polymer modification. Recommended storage at low temperature preserves stability and performance.
- Bifunctional primary amine termini for crosslinking and conjugation.
- Ether-rich PEG backbone provides flexibility and solubility in polar solvents.
- High reported purity (97.45% by LCMS) supports reproducible chemistry.
- Liquid form simplifies handling and solution preparation.
- Cold-storage stability extends usable shelf life when stored as recommended.
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TARGETMOL CHEMICALS INC CONIVAPTAN HYDROCHLORIDE 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 200 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Conivaptan hydrochloride (Vaprisol) is an orally active vasopressin V2 and V1A receptor antagonist used in the therapy of hypervolemic hyponatremia and euvolemic. purity: 99%
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