Tetrapyrroles and derivatives
Cayman Chemical N-methyl Protoporphyrin IX, Purity: ≥95% (a mixture of isomers), CAS: 79236-56-9, 5 mg
A transition state analog that potently inhibits protoporphyrin IX ferrochelatase (Ki = 10 nM), blocking the terminal step of the heme biosynthetic pathway
Apexbio Technology LLC Tin protoporphyrin IX dichloride(Synonyms: Tin Protoporphyrin Dichloride, SnPP, SnPP IX, Tin(IV) Protoporphyrin Dichloride), 25mg, CAS: 14325-05-4.
Tin protoporphyrin IX dichloride (CAS 14325-05-4) is a synthetic metalloporphyrin analog that selectively inhibits heme oxygenase-2 (HO-2) an enzyme abundant in neuronal and endothelial tissues responsible for catalyzing heme breakdown into biliverdin and carbon monoxide (CO) It shows selectivity for HO over endothelial nitric oxide synthase and soluble guanylyl cyclase with IC50 values of 35 and 30 nM respectively In rat neonates administration of this compound suppresses the physiological increase in HO activity post-birth and prevents neonatal hyperbilirubinemia demonstrating utility in biomedical research on heme metabolism pathways
Cayman Chemical Methylcobalamin, Purity: ≥98%, CAS: 13422-55-4, 500 mg
An analog of vitamin B12 with diverse neurological activities; promotes neurite outgrowth and survival in primary CGN and DRG cells and activation of ERK1/2 and Akt from 0.1-100 µM; improves sensory function in a pinch test and increases toe spreading in a rat model of sciatic nerve injury at 1 mg/kg per day; decreases the number of atypical mitochondria in the sciatic nerve and reduces vincristine-induced mechanical allodynia and thermal hyperalgesia in a rat model of neuropathic pain; reduces muscle weakness and forelimb contracture and increases bicep muscle weight and the number of musculocutaneous nerves in the wobbler mouse model of ALS; enhances the recovery of compound muscle action potentials and motor end plate innervation and decreases the time to sticker removal in the sticker removal grooming test in a rat model of bicep ulnar to musculocutaneous nerve transfer
Sigma Aldrich Fine Chemicals Biosciences Bilirubin Oxidase from Myr
We are committed to bringing younbspGreenernbspAlternative Products which adhere to one or more of The 12 Principles ofnbspGreenernbspChemistry. This product has been enhanced for energy efficiency and waste prevention when used in biofuel cell research. for more information see the article in biofiles.Bilirubin oxidase (BOD) belongs to the sub class of multicopper oxidase family. It is usually found in fungi.
Research Products International Corp Cyanocobalamin (Vitamin B12), 100 Milligrams
Common vitamin of the Vitamin B12 family.
Sigma Aldrich Fine Chemicals Biosciences Cytochrome c from equine heart, 9007-43-6, MFCD00130890, 50 mg
≥95% (SDS-PAGE), Synonym: Cytochrome c from horse heart. The specific sites and extent of oxidation in horse cytochrome c treated with H2O2 and UV were characterized. It was suggested that the state of these sites could be used as a biomarker for the oxidative environment in a cell.
Abcam P5091, USP-7 inhibitor, 25MG
MW 348.2 Da, Purity >98%. Potent, selective and cell-permeable USP-7 inhibitor (EC₅₀ = 4.2 μM). Induces apoptosis in cancer cells in vitro. Antiangiogenic and antitumor agent. Active in vitro and in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Verteporfin (Visudyne), Benzoporphyrin derivative, 25MG
MW 718.8 Da, Purity >96%. Benzoporphyrin derivative. Antiangiogenic agent. Produces ROS on stimulation with nonthermal red light in the presence of oxygen. Prevents corneal neovascularization and shows antitumor effects in vivo. .
The product is subject to the following: Abcam Restricted Use Statement
Abcam ENMD-1068, protease-activated receptor 2 (PAR2) anatagonist, 25MG
MW 283.41 Da, Purity >99%. Selective protease-activated receptor 2 (PAR2) antagonist (IC₅₀ = 1.2 mM). Anti-inflamatory agent. Active in vivo and in vitro.
The product is subject to the following: Abcam Restricted Use Statement
Abcam ODQ, NO-sensitive guanylyl cyclase inhibitor, 50MG
MW 187.15 Da, Purity >99%. Selective, potent inhibitor of nitric oxide-sensitive guanylyl cyclase. Achieve your results faster with highly validated, pure and trusted compounds.
The product is subject to the following: Abcam Restricted Use Statement
Abcam (Arg8)-Vasopressin (AVP), Vasopressin receptor agonist, 5MG
MW 1084.2 Da, Purity >95%. (Arg8)-Vasopressin (AVP), Vasopressin receptor agonist. Achieve your results faster with highly validated, pure and trusted compounds.
The product is subject to the following: Abcam Restricted Use Statement
Abcam PD 168077 maleate, D4 agonist, 50MG
MW 450.49 g/mol, Purity >98%. Potent, selective D₄ dopamine receptor agonist. Displays >400-fold selectivity over D₂ and >300-fold selectivity over D₃ subtypes (Ki values are 11.9, 2540, and 1050 nM for D₄, D₃, and D₂ receptors, respectively). Reverses object recognition deficits.
The product is subject to the following: Abcam Restricted Use Statement
Abcam UDP-glucose, Highly P2Y14 agonist, 100MG
MW 610.27 Da. Highly potent, endogenous P2Y14 agonist (EC50 = 82 nM). Involved in modulation of gastric function. UDP also available (ab120383).
The product is subject to the following: Abcam Restricted Use Statement
Abcam x estospongin C, IP3 receptor antagonist, 10UG
MW 446.72 g/mol, Purity >90%. Potent, selective, reversible IP₃ receptor antagonist (IC₅₀ = 350 nM). Inhibits IP₃-mediated Ca²+ release from ER and SR. 30-Fold selectivity over ryanodine receptor. Inhibits voltage-dependent Ca²+ and K+ channels at higher concentrations. Cell-permeable.
The product is subject to the following: Abcam Restricted Use Statement
Abcam SB 505124, ALK5 inhibitor, 10MG
MW 335.4 Da, Purity >98%. Potent, reversible, competitive ALK5 inhibitor (IC₅₀ values are 47 and 129 nM for ALK5 and ALK4 respectively). Inhibits ALK7 but not ALK1, 2, 3, or 6. Shows antifibrotic effects in vivo. .
The product is subject to the following: Abcam Restricted Use Statement