Tetrapyrroles and derivatives
Abcam SB-277011-A dihydrochloride, D3 antagonist, 25MG
MW 511.5 Da, Purity >98%. Potent, highly selective D3 receptor antagonist (pKi = 7.95 at hD3 receptors). Exhibits over 100-fold selectivity over D2 receptors. Blood-brain barrier (BBB) permeable. Diminishes nicotine, cocaine and alcohol self-administration. Interferes with mechanisms of drug-taking and reinstatement of drug-taking behaviours.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Paprotrain, MKLP-2 inhibitor, 1MG
MW 245.28 Da, Purity >98%. Selective cell-permeable MKLP-2 inhibitor. Reversible ATP-noncompetitive ATPase inhibitor (IC₅₀ values are 1.35 and 0.83 μM for basal and microtubule-stimulated activity respectively). Inhibits Aurora B. Induces cell cycle arrest at early metaphase I.
The product is subject to the following: Abcam Restricted Use Statement
Apexbio Technology LLC Methylcobalamin 13422-55-4 100mg
Methylcobalamin (CAS 13422-55-4) is a biologically active form of vitamin B12 featuring a methyl group as the ligand to the cobalt ion within the cobalamin structure Functioning as a coenzyme for methionine synthase it facilitates the remethylation of homocysteine to methionine an essential step in methylation metabolism and nucleic acid synthesis Due to its direct involvement in methyl group transfers methylcobalamin is widely utilized in biomedical research to investigate cellular methylation processes nervous system function and disorders related to vitamin B12 deficiency
Sigma Aldrich Fine Chemicals Biosciences 5,10,15,20-Tetrakis(4-hydroxyphenyl)-21H,23H-porphine Dye content 95 % | 51094-17-8 | MFCD00191501 | 1G
5,10,15,20-Tetrakis(4-hydroxyphenyl)-21H,23H-porphine Dye content 95 % | Mol Wt: 678.73 | 51094-17-8 | MFCD00191501 | 1G
eMolecules Zinc phthalocyanine | 14320-04-8 | MFCD00041955 | 25g
Combi-Blocks | Zinc phthalocyanine | 25g | 296392447 | QC-0016 | 95.000 | 14320-04-8 | MFCD00041955 | 577.920 | C32H16N8Zn
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Apexbio Technology LLC Bilirubin 635-65-4 10mM (in 1mL DMSO)
Bilirubin (CAS 635-65-4) is a bile pigment naturally produced from the catabolism of heme It exhibits antioxidant properties primarily via scavenging reactive oxygen species and inhibiting oxidative modification of biomolecules Bilirubin modulates signaling pathways associated with inflammation oxidative stress and cellular apoptosis rendering it relevant in biomedical research focused on hepatic disorders cardiovascular disease and neurodegenerative conditions Originally identified from bezoar bilirubin requires storage under airtight cool and dry conditions to maintain stability
Abcam Monosodium urate, Pro-inflammatory agent, 2MG
MW 190.09 Da. NLRP3/NALP3 inflammasome activator. Stimulates caspase-1 activating NLRP3/NALP3 inflammasome, results in active IL-1β and IL-18 production. Active in vitro and in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Sigma Aldrich Fine Chemicals Biosciences Vitamin B12 | 68-19-9 | MFCD00151092 | 5 g
Vitamin B12 | Purity: ≥98% | Mol Wt: 1355.37 | 68-19-9 | MFCD00151092 | 5 g
Abcam Undecylprodigiosin, Apoptotic and anticancer agent, 250UG
MW 393.6 Da, Purity >93%. Apoptotic and anticancer agent. Selectively induces p53-independant apoptosis in cancer cells. Induces G2/M cell cycle arrest and shows antiproliferative effects. Shows antimalarial and antibactieral effects in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Medchemexpress LLC Bilirubin conjugate disodium | 68683-34-1 | MFCD00044931 | 95.0% | C37H44N6Na2O10S2 | 10MG
Bilirubin conjugate disodium is a water-soluble, ditaurate derivative of bilirubin used as a research reagent and drug-metabolite reference for studies of heme metabolism and assay development. The material is supplied as the disodium salt (C37H44N6Na2O10S2) and is accompanied by analytical documentation for laboratory use.
- High purity (95.0%).
- Water-soluble disodium salt for aqueous assays.
- Suitable as a reference standard in bilirubin and drug-metabolite studies.
- Provided with certificate of analysis and safety data sheet.
- Available in small quantity packages for research applications.
Sigma Aldrich Fine Chemicals Biosciences 5,10,15,20-Tetraphenyl-21H,23H-porphine 97% | 917-23-7 | MFCD00011680 | 5G
5,10,15,20-Tetraphenyl-21H,23H-porphine 97% | Purity: 97% | Mol Wt: 614.74 | 917-23-7 | MFCD00011680 | 5G
Abcam TPEN, Metal ion chelator, 100MG
MW 424.5 Da, Purity >99%. Metal ion chelator. Decreases intracellular zinc levels. Induces apoptosis. Causes defects in oocyte maturation. Modulates hippocampal neurogenesis following seizure. Cell permeable. Active in vivo and in vitro.
The product is subject to the following: Abcam Restricted Use Statement
TARGETMOL CHEMICALS INC Hematoporphyrin monomethyl eth
Also available in 1 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Hematoporphyrin monomethyl ether is a porphyrin photosensitizer that can be used in studies of port wine stains.