Thiophenes
Medchemexpress LLC Acetyl-CoA Carboxylase-IN-1 | 179343-23-8 | C13H9Br2N5 | 25 MG
Acetyl-CoA Carboxylase-IN-1 is a potent acetyl-CoA carboxylase (ACC) inhibitor with an IC50 value of less than 5 nM, demonstrated to exhibit antibacterial activity. It is available as an off-white to light yellow solid powder and is soluble in DMSO, making it suitable for various laboratory applications.
- Potent acetyl-CoA carboxylase (ACC) inhibitor with an IC50 value of less than 5 nM
- Exhibits antibacterial activity against E. coli
- Soluble in DMSO for in vitro applications
- Long-term stability when stored as a powder at -20°C (3 years) or 4°C (2 years)
- Stable in solvent at -80°C (6 months) or -20°C (1 month)
Selleck Chemical LLC NVP-BSK805 2HCl S2686-1g
NVP-BSK805 2HCl is a potent and selective ATP-competitive JAK2 inhibitor with IC50 of 0 5 nM 20-fold selectivity towards JAK1 JAK3 and TYK2
eMolecules 6165-68-0 | Thiophen-2-ylboronic acid | Ambeed | MFCD00151850 | 127.950 | C4H5BO2S | 98.000 | OB(O)c1cccs1 | 100g | 600835001
Thiophen-2-ylboronic acid | Ambeed | 6165-68-0 | MFCD00151850 | 127.950 | C4H5BO2S | 98.000 | OB(O)c1cccs1 | 100g | 600835001
Medchemexpress LLC 1,4-pentanediamine, N4-(6-chloro-2-methoxy-9-acridinyl)-N1,N1-diethyl-, dihydrochloride | 56100-42-6 | 98.4% | 472.88 | 1 ML
l-Atabrine dihydrochloride is a less active enantiomer of quinacrine that displays antiprion activity. It is a light yellow to yellow solid with a purity of 98.35%.
- Displays antiprion activity.
- Intended for research use only.
- Soluble in H₂O and DMSO.
- Ships at room temperature.
- Store at 4°C, sealed, away from moisture.
- When in solvent, store at -80°C for 6 months or -20°C for 1 month.
Apexbio Technology LLC Pramipexole dihydrochloride 104632-25-9 20mg
Pramipexole dihydrochloride is a small-molecule agonist targeting dopamine receptors exhibiting selective affinity toward the D3 dopamine receptor subtype and lower affinity for the D2L D2S and D4 subtypes It is designed to stimulate dopamine receptor-mediated signaling thereby modulating dopaminergic pathways involved in motor function Pramipexole dihydrochloride exerts its biological activity primarily through dopamine receptor agonism and also demonstrates receptor-independent neuroprotective effects by attenuating mitochondrial reactive oxygen species (ROS) production and decreasing apoptosis-related signaling cascades Based on these pharmacological properties pramipexole dihydrochloride holds research potential in exploring dopaminergic system involvement and neuroprotective mechanisms relevant to neurodegenerative conditions such as Parkinson s disease and restless legs syndrome
![eMolecules 20332-16-5 | 6-AMINOBENZO[D][1,3]DIOXOLE-5-CARBOXYLIC ACID | AstaTech | MFCD00016650 | 181.147 | C8H7NO4 | 95.000 | Nc1cc2OCOc2cc1C(O)=O | 1g | 528280288](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502170303.JPG-250.jpg)
eMolecules 20332-16-5 | 6-AMINOBENZO[D][1,3]DIOXOLE-5-CARBOXYLIC ACID | AstaTech | MFCD00016650 | 181.147 | C8H7NO4 | 95.000 | Nc1cc2OCOc2cc1C(O)=O | 1g | 528280288
6-AMINOBENZO[D][1,3]DIOXOLE-5-CARBOXYLIC ACID | AstaTech | 20332-16-5 | MFCD00016650 | 181.147 | C8H7NO4 | 95.000 | Nc1cc2OCOc2cc1C(O)=O | 1g | 528280288
Apexbio Technology LLC 4-Methylhistamine dihydrochloride 36376-47-3 1mg
4-Methylhistamine dihydrochloride (CAS 36376-47-3) is a selective agonist for the histamine H4 receptor (H4R) displaying a pEC50 of 7 4 0 1 at human H4R It exhibits over 100-fold selectivity for H4R relative to H3R and H2R and over 100 000-fold compared to H1R While affinity for human H4R is moderate it binds rat and mouse H4R with higher affinity (Ki values of 73 nM and 55 nM respectively) In in vivo models 4-Methylhistamine dihydrochloride modulates inflammatory signaling elevating TNF- and NF- B expression via JAK/STAT pathways in response to LPS-induced joint inflammation It serves as a valuable tool in studies of H4R-mediated immune regulation and inflammatory mechanisms
eMolecules 6165-68-0 | Thiophen-2-ylboronic acid | Ambeed | MFCD00151850 | 127.950 | C4H5BO2S | 98.000 | OB(O)c1cccs1 | 5g | 552669675
Thiophen-2-ylboronic acid | Ambeed | 6165-68-0 | MFCD00151850 | 127.950 | C4H5BO2S | 98.000 | OB(O)c1cccs1 | 5g | 552669675
Medchemexpress LLC 2-Methylthiophene | 554-14-3 | 99.94% | 98.16 | 5 G
2-Methylthiophene is an intermediate used in the synthesis of aromatic sulfur compounds. It is for research use only and not sold to patients. It appears as a colorless to light yellow liquid.
- Purity: 99.94%
- Available in various sizes
- Documentation includes Data Sheet, COA, SDS, and Handling Instructions
- Soluble in DMSO for in vitro use
- Storage at 4°C under nitrogen
Medchemexpress LLC Alexidine dihydrochloride | 1715-30-6 | 99.7% | 581.71 | 10 MG
Alexidine dihydrochloride is an anticancer agent that targets a mitochondrial tyrosine phosphatase, PTPMT1, in mammalian cells and causes mitochondrial apoptosis. It also has antifungal and antibiofilm activity against a diverse range of fungal pathogens.
- Anticancer agent targeting mitochondrial tyrosine phosphatase, PTPMT1.
- Causes mitochondrial apoptosis.
- Antifungal and antibiofilm activity against a diverse range of fungal pathogens.
- Displays activity against most Candida spp., including fluconazole-resistant isolates.
- Complete inhibition of filamentation or proliferation of imaged fungi.
- Able to decimate mature biofilms of Candida, Cryptococcus, and Aspergillus spp. at low concentrations.
- Inhibits fungal biofilm growth and viability in a murine biofilm model.
Medchemexpress LLC Histamine dihydrochloride | 56-92-8 | 99.9% | 25 MG
Histamine dihydrochloride is an organic nitrogen compound that participates in local immune responses, regulates intestinal physiological functions, and acts as a neurotransmitter. It is also an agonist for the histamine receptor and a vasodilator. It affects the p38 MAPK/Akt signaling pathway and shows antitumor, antioxidant, and anti-inflammatory activities.
- Regulates intestinal physiological functions
- Acts as a neurotransmitter
- Affects the p38 MAPK/Akt signaling pathway
- Shows antitumor, antioxidant, and anti-inflammatory activities
- Used in research for acute myeloid leukemia, malignant melanoma, and renal cell carcinoma
Medchemexpress LLC d-Atabrine dihydrochloride | 56100-41-5 | 99.6% | 472.88 | 1 ML
d-Atabrine dihydrochloride is an active enantiomer of quinacrine which displays antiprion activity.
- Purity of 99.64%
- Molecular weight of 472.88
- Appears as a solid
- Color is light yellow to yellow
- Recommended storage at 4°C, sealed, away from moisture
- For solutions, store at -80°C for 6 months or -20°C for 1 month, sealed and away from moisture
eMolecules 36052-27-4 | 3-Amino-pyridine-2-carboxylic acid methyl ester | J & W PharmLab LLC | MFCD08695602 | 152.153 | C7H8N2O2 | 96.000 | COC(=O)c1ncccc1N | 1g | 525324906
3-Amino-pyridine-2-carboxylic acid methyl ester | J & W PharmLab LLC | 36052-27-4 | MFCD08695602 | 152.153 | C7H8N2O2 | 96.000 | COC(=O)c1ncccc1N | 1g | 525324906
Medchemexpress LLC Lomerizine dihydrochloride | 101477-54-7 | 99.95% | 50 MG
Lomerizine dihydrochloride is an antagonist of L- and T-type voltage-gated calcium channels. It also antagonizes transient receptor potential channel 5. Lomerizine is a dual L/T-type channel blocker that is used for prophylaxis of migraine.
- Antagonist of L- and T-type voltage-gated calcium channels.
- Demonstrates neuroprotective effects.
- Possesses activity in reversing multidrug resistance.
- Increases cerebral blood flow.
Medchemexpress LLC (E)-1,3-Di(thiophen-2-yl)prop-2-en-1-one | 42811-88-1 | 99.4% | 220.31 | 250 MG
(E)-1,3-Di(thiophen-2-yl)prop-2-en-1-one is a chemical compound primarily used as a drug intermediate for the synthesis of various active compounds. It is intended for laboratory research by experienced personnel in appropriately equipped and authorized facilities and has not been fully validated for medical applications.
- Used as a drug intermediate for synthesizing active compounds.
- Intended for laboratory research.
- Appears as a light yellow to yellow solid.
- Requires storage in a cool, well-ventilated area, away from direct sunlight and ignition sources.
- Store powder at -20°C for 3 years, or 4°C for 2 years.
- When in solvent, store at -80°C for 6 months, or -20°C for 1 month.
- Avoid breathing dust or vapors.
- Wear appropriate personal protective equipment during handling.