Thiophenes
Medchemexpress LLC RWJ-56110 dihydrochloride | 2387505-58-8 | 99.9% | 863.65 | 25 MG
RWJ-56110 dihydrochloride is a potent, selective, peptide-mimetic inhibitor of PAR-1 activation and internalization (binding IC50=0.44 uM) and shows no effect on PAR-2, PAR-3, or PAR-4. It inhibits the aggregation of human platelets induced by both SFLLRN-NH2 (IC50=0.16 μM) and thrombin (IC50=0.34 μM), demonstrating selectivity relative to U46619. This compound also blocks angiogenesis, the formation of new vessels in vivo, and induces cell apoptosis.
- Potent and selective PAR-1 inhibitor.
- Inhibits human platelet aggregation.
- Blocks angiogenesis and new vessel formation.
- Induces cell apoptosis.
Medchemexpress LLC Lomerizine dihydrochloride | 101477-54-7 | 99.9% | 100 MG
Lomerizine dihydrochloride is an antagonist of L- and T-type voltage-gated calcium channels. It is intended for research use only.
- Antagonist of L- and T-type voltage-gated calcium channels
- Neuroprotective in motor neurons
- Increases cerebral blood flow
- Reverses multidrug resistance by inhibiting P-gp function
eMolecules (3-Pyridyl)-thiophen-2-yl-methanol | 21314-77-2 | MFCD01108848 | 250mg
Chem-Impex | (3-Pyridyl)-thiophen-2-yl-methanol | 250mg | 449074524 | 23309 | | 21314-77-2 | MFCD01108848 | 191.250 | C10H9NOS
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool
Medchemexpress LLC 2-Amino-2-(thiophen-3-yl)acetic acid | 38150-49-1 | 157.19 | 100 MG
2-Amino-2-(thiophen-3-yl)acetic acid is a glycine derivative primarily used as an ergogenic supplement. It is recognized as a beneficial dietary substance that can influence anabolic hormone secretion, support fuel supply during exercise, enhance mental performance during stress, and help prevent exercise-induced muscle damage.
- Influences secretion of anabolic hormones
- Supplies fuel during exercise
- Enhances mental performance during stress-related tasks
- Prevents exercise-induced muscle damage
Medchemexpress LLC Puromycin dihydrochloride | 58-58-2 | 99.9% | 1 ML
Puromycin dihydrochloride is an aminonucleoside antibiotic that inhibits protein synthesis by blocking aminoacyl-sRNA formation, leading to the accumulation of small peptides. It causes premature termination of translation by linking non-specifically to growing polypeptide chains. When used in minimal amounts, puromycin incorporation in newly synthesized proteins directly reflects the rate of mRNA translation in vitro.
- Acts as an analog of the 3' end of aminoacyl-tRNA.
- Inhibits protein synthesis by interfering with translation.
- Can be used for direct evaluation of translation activity in single cells by immunofluorescence microscopy.
- Suitable for heterogeneous populations of cells by fluorescence-activated cell sorting.
eMolecules 104680-25-3 | Diethyl 2-aminothiophene-3,4-dicarboxylate | MFCD08059079 | 1g
Ambeed | [124]Triazolo[43-a]pyridin-6-amine | 100mg | 490491955 | A107576 | 1082448-58-5 | MFCD11597277 | 134.142 | C6H6N4
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool
Selleck Chemical LLC BGP-15 2HCl
BGP-15 is a nicotinic amidoxime derivative with PARP inhibitory activity It has been demonstrated that BGP-15 protects against ischemia-reperfusion injury
Apexbio Technology LLC DMAB-anabaseine dihydrochloride 154149-38-9 10mg
DMAB-anabaseine dihydrochloride (CAS 154149-38-9) is a small-molecule partial agonist and antagonist targeting neuronal 7 nicotinic acetylcholine receptors (nAChRs) It is designed to modulate receptor-mediated neurotransmission thereby influencing cognitive-related neuronal signaling pathways DMAB-anabaseine dihydrochloride exerts its biological activity primarily through selective partial activation of 7 nAChRs and antagonism at other subtypes such as 4 2 Based on these pharmacological properties DMAB-anabaseine dihydrochloride holds research potential in studies of nicotinic receptor function neural signaling mechanisms and cognitive-related conditions
Selleck Chemical LLC Trifluoperazine 2HCl S3201-10mM/1mL
Trifluoperazine (NSC-17474 RP-7623 SKF-5019) 2HCl is a dopamine D2 receptor inhibitor with IC50 of 1 1 nM Trifluoperazine also inhibits calmodulin (CaM)
Medchemexpress LLC 1,4-pentanediamine, N4-(6-chloro-2-methoxy-9-acridinyl)-N1,N1-diethyl-, dihydrochloride | 56100-42-6 | 98.4% | 472.88 | 1 ML
l-Atabrine dihydrochloride is a less active enantiomer of quinacrine that displays antiprion activity. It is a light yellow to yellow solid with a purity of 98.35%.
- Displays antiprion activity.
- Intended for research use only.
- Soluble in H₂O and DMSO.
- Ships at room temperature.
- Store at 4°C, sealed, away from moisture.
- When in solvent, store at -80°C for 6 months or -20°C for 1 month.
Apexbio Technology LLC Pramipexole dihydrochloride 104632-25-9 20mg
Pramipexole dihydrochloride is a small-molecule agonist targeting dopamine receptors exhibiting selective affinity toward the D3 dopamine receptor subtype and lower affinity for the D2L D2S and D4 subtypes It is designed to stimulate dopamine receptor-mediated signaling thereby modulating dopaminergic pathways involved in motor function Pramipexole dihydrochloride exerts its biological activity primarily through dopamine receptor agonism and also demonstrates receptor-independent neuroprotective effects by attenuating mitochondrial reactive oxygen species (ROS) production and decreasing apoptosis-related signaling cascades Based on these pharmacological properties pramipexole dihydrochloride holds research potential in exploring dopaminergic system involvement and neuroprotective mechanisms relevant to neurodegenerative conditions such as Parkinson s disease and restless legs syndrome
Selleck Chemical LLC GSK-LSD1 2HCl
GSK-LSD1 2HCl is an irreversible and selective LSD1 inhibitor with IC50 of 16 nM 1000 fold selective over other closely related FAD utilizing enzymes (i e LSD2 MAO-A MAO-B)
Medchemexpress LLC Merestinib dihydrochloride | 1206801-37-7 | 99.4% | 625.45 g·mol⁻¹ | C30H24Cl2F2N6O3 | 10 MG
Merestinib dihydrochloride is the dihydrochloride salt of merestinib (LY2801653), an orally bioavailable small-molecule multi-kinase inhibitor supplied for preclinical research. It potently inhibits c-Met and has reported activity against several oncogenic kinases, and is provided as a characterized reagent with supporting analytical data.
- Potent c-Met inhibitor with reported Ki ≈ 2 nM.
- Activity against multiple kinases including MST1R, FLT3, AXL, MERTK, TEK, ROS1, DDR1/2, and MKNK1/2.
- Orally bioavailable small-molecule suitable for in vitro and in vivo preclinical studies.
- Characterized reagent with molecular formula C30H24Cl2F2N6O3 and molecular weight 625.45 g·mol⁻¹.
- High purity confirmed by LCMS (≈99.4%).
Selleck Chemical LLC Latrepirdine 2HCl S1245-10mg
Latrepirdine is an orally active and neuroactive antagonist of multiple drug targets including histamine receptors GluR and 5-HT receptors used as an antihistamine drug
![eMolecules 6-AMINOBENZO[D][1,3]DIOXOLE-5-CARBOXYLIC ACID | 20332-16-5 | MFCD00016650 | 1g](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502170303.JPG-250.jpg)
eMolecules 6-AMINOBENZO[D][1,3]DIOXOLE-5-CARBOXYLIC ACID | 20332-16-5 | MFCD00016650 | 1g
AstaTech | 6-AMINOBENZO[D][1,3]DIOXOLE-5-CARBOXYLIC ACID | 1g | 528280288 | 87187 | 95.000 | 20332-16-5 | MFCD00016650 | 181.147 | C8H7NO4
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool