Carboximidamides
Medchemexpress LLC PDE12-IN-1 | 2259620-80-7 | 98.9% | 616.48 | C31H27BrFN5O3 | 10 MG
PDE12-IN-1 is a selective phosphodiesterase 12 (PDE12) inhibitor provided for laboratory research use. It shows potent enzyme inhibition and modulates 2′,5′-linked adenylate polymer levels in cellular assays. Intended for in vitro biochemical and cell-based studies; not for human or clinical use.
- Selective PDE12 inhibition with reported pIC50 ≈ 9.1.
- Suitable for biochemical and cellular assays.
- High purity: 98.9%.
- Available in small pack sizes for screening and optimization.
- Molecular formula C31H27BrFN5O3; molecular weight 616.48.
Medchemexpress LLC Creatine monohydrate | 6020-87-7 | MFCD00071582 | 100.0% | 149.15 g/mol | C4H11N3O3 | 100 MG
Creatine monohydrate is an endogenous amino acid derivative that supports cellular energy metabolism by replenishing ATP via the creatine-phosphocreatine system, with prominent roles in muscle and brain. It is commonly used in research on bioenergetics, muscle physiology, and neuroprotection, and shows effects on protein synthesis, antioxidant activity, and short-duration, high-intensity exercise performance.
- Supports ATP regeneration and cellular energy.
- Promotes protein synthesis and muscle hypertrophy.
- Scavenges free radicals, protecting cellular components.
- White to off-white solid suitable for laboratory handling.
- High purity appropriate for research applications.
Medchemexpress LLC Allantoin (Standard) | 97-59-6 | MFCD00005260 | 158.12 | 25 MG
Allantoin (Standard) is the analytical standard of Allantoin, intended for research and analytical applications. It acts as a skin conditioning agent, promoting healthy skin and stimulating new, healthy tissue growth. This compound is typically used as an analytical standard for assays and in qualitative, quantitative, and methodological research experiments.
- Promotes healthy skin
- Stimulates new and healthy tissue growth
- Used in HPLC, GC, and MS research experiments
- Reference for assays
Apexbio Technology LLC Guanidine HCl 50-01-1 10mM (in 1mL H2O)
Guanidine hydrochloride (Guanidine HCl CAS 50-01-1) is a highly alkaline crystalline compound derived from the oxidative metabolism of guanine Functioning primarily as a strong chaotropic agent it disrupts hydrogen bonding and secondary structure in proteins leading to efficient protein denaturation and solubilization Widely utilized in molecular biology and biochemistry Guanidine HCl facilitates protein unfolding for downstream applications such as protein purification refolding studies and RNA extraction protocols where it also serves to inactivate nucleases and other enzymes
Alkali Scientific Guanidine Hydrochloride, 100 G
Guanidine Hydrochloride is a high-purity chaotropic agent commonly used in protein denaturation and nucleic acid isolation. This 100g sample is essential in disrupting protein structures for biochemical studies, facilitating the extraction of RNA, DNA, and proteins in molecular biology protocols. Its strong denaturing properties make it ideal for breaking down protein tertiary and quaternary structures, ensuring the efficient isolation of nucleic acids. It is also used in the preparation of buffers for experiments involving enzymatic activity and in studies of protein folding and structure. Guanidine Hydrochloride is indispensable in many molecular and biochemical laboratories.
Medchemexpress LLC Ask1-in-2 | 2541792-70-3 | MFCD11217007 | 99.6% | C19H17FN6O | 10MG
ASK1-IN-2 is a small-molecule, orally active inhibitor of apoptosis signal-regulating kinase 1 (ASK1) with a reported biochemical IC50 of 32.8 nM. Supplied as a high-purity research chemical (CAS 2541792-70-3; formula C19H17FN6O), it is available as a solid powder and as a 10 mM solution in DMSO for use in in vitro and in vivo preclinical studies, including research into inflammatory conditions such as ulcerative colitis.
- Potent ASK1 inhibition (IC50 32.8 nM).
- Orally active small molecule suitable for in vivo studies.
- High purity (99.6%).
- Available as solid powder and as 10 mM solution in DMSO.
- Suitable for research into inflammatory diseases such as ulcerative colitis.
- Provided with safety data sheet and product documentation.
Medchemexpress LLC Ripk3-in-1 | 2361139-70-8 | 99.3% | C29H25FN4O4 | 10MG
RIPK3-IN-1 is a small-molecule, type II DFG-out inhibitor of receptor-interacting protein kinase 3 (RIPK3) intended for research use in biochemical and cellular studies. It exhibits potent biochemical activity and is supplied as a high-purity compound suitable for in vitro investigations into necroptosis and related signaling pathways.
- Potent RIPK3 inhibition, IC50 = 9.1 nM.
- High purity, 99.3% by supplier analysis.
- Chemical formula C29H25FN4O4 and molecular weight 512.53 g/mol.
- Suitable for biochemical and cellular assays targeting necroptosis pathways.
- Available in multiple sizes to support assay development and scale-up.
eMolecules 1399191-70-8 | Ambeed | 55-(14-Phenylene)dipicolinaldehyde | 100mg | 603089926 | A1226399 | 288.306 | C18H12N2O2
Medchem Express | SB 242084 | 5mg | 446262835 | HY-13409 | 181632-25-7 | MFCD05662310 | 394.860 | C21H19ClN4O2
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![Medchemexpress LLC Pyrrolo[3,4-b]pyrrole-5(1H)-carboxamide, N-[4-(3-ethynylphenyl)amino-7-methoxy-6-quinazolinyl]hex... | 1353644-70-8 | MFCD00038264 | 99.7% | 442.51 g/mol | C25H26N6O2 | 100 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000242505.png-250.jpg)
Medchemexpress LLC Pyrrolo[3,4-b]pyrrole-5(1H)-carboxamide, N-[4-(3-ethynylphenyl)amino-7-methoxy-6-quinazolinyl]hex... | 1353644-70-8 | MFCD00038264 | 99.7% | 442.51 g/mol | C25H26N6O2 | 100 MG
Theliatinib is a potent, ATP-competitive, orally active, and highly selective epidermal growth factor receptor (EGFR) inhibitor provided for research use. It shows low nanomolar cellular activity against EGFR and has been evaluated in preclinical models of EGFR-driven cancers.
- Potent EGFR inhibition (Ki ≈ 0.05 nM; IC50 ≈ 3 nM).
- Highly selective for EGFR over common off-target kinases.
- Suitable for in vitro and in vivo preclinical studies.
- High reported purity for reliable assay results.
- Formulation as a solid; soluble in DMSO for assay preparation.
Medchemexpress LLC Surfactin | 252023-70-4 | 98.96% | 50 MG
Surfactin is a potent cyclic lipopeptide biosurfactant consisting of four isomers (Surfactin A, B, C, and D). It mediates the flux of mono- and divalent cations, such as calcium, across lipid bilayer membranes. Surfactin acts as an antimicrobial adjuvant with antibacterial, antifungal, antimycoplasma, and hemolytic effects, and has antiviral activity against various enveloped viruses.
- Potent cyclic lipopeptide biosurfactant
- Consists of four isomers
- Mediates flux of mono- and divalent cations across lipid bilayer membranes
- Acts as an antimicrobial adjuvant
- Exhibits antibacterial, antifungal, and antimycoplasma effects
- Has antiviral activity against various enveloped viruses
Medchemexpress LLC Guanidine hydrochloride | 50-01-1 | 98.0% | 100 G
Guanidine hydrochloride | 50-01-1 | 98.0% | 100 G
Medchemexpress LLC AN0128 | 872044-70-7 | 98.95% | 400.06 | 10 MG
AN0128 is a boron-containing antibacterial and anti-inflammatory agent. It has demonstrated efficacy against *S. aureus*, *S. epidermidis*, *P. acnes*, and *B. subtilis* with minimum inhibitory concentration (MIC) values of 1, 0.5, 0.3, and 1 μg/mL, respectively. This product is intended for research in periodontal and cutaneous diseases.
- Acts as an antibacterial agent.
- Functions as an anti-inflammatory agent.
- Inhibits the release of pro-inflammatory cytokines (TNF-α, IL-1β) in human peripheral blood mononuclear cells (PBMCs) at 10 μM.
- Reduces inflammatory infiltrate and bone loss in experimental periodontitis.
- Shows greater effectiveness than a common toothpaste in reducing bone loss and increasing bone volume in animal models of periodontitis.
- Available in solid form, white to off-white in color.