Carboximidamides
eMolecules 2229025-70-9 | Medchem Express | WM-3835 | 5mg | 599150697 | HY-134901 | 400.42 | C20H17FN2O4S
Ambeed | alpha-Pyrone | 100mg | 570569947 | A612059 | 504-31-4 | MFCD00006639 | 96.085 | C5H4O2
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Medchemexpress LLC Triphenylphosphonium-derivatized anethole dithiolethione (mitochondria-targeting H2S donor) | 1429061-80-2 | 96.4% | 721.77 g/mol | C37H38BrO2PS3 | 25MG
AP39 is a mitochondria-targeted hydrogen sulfide (H2S) donor used in biomedical research to elevate intracellular H2S and provide cytoprotective effects under oxidative stress. It is a triphenylphosphonium-derivatized anethole dithiolethione reported to preserve mitochondrial DNA integrity and to protect against myocardial reperfusion injury in preclinical models, with potential applications in neurodegenerative disease research.
- Targets mitochondria to deliver hydrogen sulfide intracellularly.
- Provides cytoprotective effects under oxidative stress.
- Reported to preserve mitochondrial DNA integrity.
- Demonstrated efficacy in preclinical myocardial reperfusion models.
- Available as a solid in multiple milligram pack sizes for research use.
Medchemexpress LLC Melagatran | 159776-70-2 | 99.3% | 10 MG
Melagatran is a reversible, selective, orally active direct inhibitor of thrombin with a Ki of 2 nM. It directly binds to the active site of thrombin, inhibiting the thrombin-mediated conversion of fibrinogen to fibrin. Melagatran reduces the DNA binding activity of NF-κB and AP-1, and has shown to reduce fibrin deposition in organs, alleviate ischemic brain damage, and reduce the size of advanced atherosclerotic lesions.
- Reversible, selective thrombin inhibitor
- Inhibits thrombin-mediated fibrinogen to fibrin conversion
- Reduces DNA binding activity of NF-κB and AP-1
- Alleviates ischemic brain damage
- Decreases advanced atherosclerotic lesion size
- Used in cardiovascular disease research
- Investigated for neurological disease studies
Medchemexpress LLC 3-O-Methylquercetin | 1486-70-0 | MFCD00210588 | 316.26 | 1 MG
3-O-Methylquercetin | 1486-70-0 | MFCD00210588 | 316.26 | 1 MG