Enamines
Selleck Chemical LLC Amlodipine S1905-1g
Amlodipine (UK-48340) is a long-acting calcium channel blocker used to lower blood pressure and prevent chest pain
Selleck Chemical LLC Cisatracurium Besylate S2113-25mg
Cisatracurium Besylate(51W89) is a nondepolarizing neuromuscular blocking agent antagonizing the action of acetylcholine by inhibiting neuromuscular transmission
eMolecules AstaTech / 2-BROMO-2-METHYL-1-MORPHOLINOPROPAN-1-ONE / 0.25g / 206677639 / 31276 / 97.000 / 13887-51-9 / MFCD12910756 / 236.109 / C8H14BrNO2
AstaTech / 2-BROMO-2-METHYL-1-MORPHOLINOPROPAN-1-ONE / 0.25g / 206677639 / 31276 / 97.000 / 13887-51-9 / MFCD12910756 / 236.109 / C8H14BrNO2
Medchemexpress LLC PF-562271 besylate | 939791-38-5 | MFCD14105612 | 99.2% | 665.66 g/mol | C27H26F3N7O6S2 | 1 ML
PF-562271 besylate is a potent, ATP-competitive, reversible inhibitor of focal adhesion kinase (FAK) and Pyk2 used in biochemical, cell-based, and in vivo research. It is supplied as a 10 mM solution in DMSO and exhibits low-nanomolar activity against FAK and nanomolar activity against Pyk2.
- Potent inhibition of FAK and Pyk2 (FAK IC50 = 1.5 nM; Pyk2 IC50 = 13 nM).
- Supplied as a ready-to-use 10 mM solution in DMSO for in vitro assays.
- High reported purity suitable for research use (99.17%).
- Demonstrated antiproliferative activity across multiple cancer cell lines.
- Validated pharmacological effects in vivo, including inhibition of FAK phosphorylation.
Medchemexpress LLC Methyl but-3-enoate 25g
Methyl but-3-enoate is a drug intermediate for synthesis of various active compounds
Apexbio Technology LLC Amlodipine 88150-42-9 1g
Amlodipine (CAS 88150-42-9) is a dihydropyridine-based small molecule that functions as a long-acting calcium channel blocker It selectively inhibits L-type calcium channels on vascular smooth muscle and cardiac myocytes thereby reducing intracellular calcium influx This action leads to vasodilation and decreased vascular resistance Amlodipine is widely utilized in biomedical research to investigate calcium signaling pathways vascular tone modulation and cardiovascular pharmacology Its mechanistic profile also makes it a reference compound in studies evaluating novel antihypertensive or vasodilatory agents
Medchemexpress LLC PF-562271 besylate | 939791-38-5 | MFCD14105612 | 99.2% | 665.7 g/mol | C27H26F3N7O6S2 | 1 MG
PF-562271 besylate is an ATP-competitive, reversible inhibitor of focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (Pyk2) used as a research tool in cell-signaling and oncology studies. It exhibits potent biochemical activity (FAK IC50 ≈ 1.5 nM; Pyk2 IC50 ≈ 13-14 nM), is supplied as the besylate salt, and is available at high purity for in vitro and in vivo research.
- Potent ATP-competitive, reversible inhibitor of FAK and Pyk2.
- Low nanomolar biochemical potency for target kinases.
- Provided as a besylate salt for improved stability and handling.
- High reported purity suitable for research applications.
- Used in cellular and animal model studies of tumor signaling pathways.
Medchemexpress LLC TO-1187 (TFA) | 98.4% | 795.72 | C36H36F3N9O9 | 10 MG
TO-1187 TFA is a selective PROTAC degrader that targets HDAC6 and recruits cereblon to promote ubiquitination and proteasomal degradation of HDAC6. Supplied as a trifluoroacetic acid salt in solid form, it is intended as a research tool for cellular and preclinical studies investigating HDAC6 biology and PROTAC-mediated target removal.
- Selective HDAC6 degrader with DC50 of 5.81 nM.
- Engages cereblon to induce ubiquitination and proteasomal degradation.
- High chemical purity (98.4%) suitable for biochemical and cellular assays.
- Provided as a solid TFA salt for stable handling and storage.
- Includes analytical documentation such as COA, H NMR, LCMS, and RP-HPLC.
- Storage recommended at 4°C under nitrogen; in solvent store at -80°C (6 months) or -20°C (1 month).
Apexbio Technology LLC Amlodipine Besylate 111470-99-6 10mM (in 1mL DMSO)
Amlodipine Besylate (CAS 111470-99-6) is a long-acting calcium channel blocker that reduces blood pressure primarily through inhibition of calcium ion influx via voltage-gated calcium channels Calcium channel modulation influences critical cellular signaling pathways In cortical neurons exposed to oxidative stress Amlodipine Besylate ( 5 M) preserves cellular viability by reducing oxidative damage enhancing pro-survival signals and suppressing apoptotic pathways It has also demonstrated proliferative effects on human epidermoid carcinoma (A431) cells Furthermore clinical studies indicate that Amlodipine Besylate decreases peripheral vascular resistance and myocardial oxygen demand in angina patients and effectively lowers arterial pressure in hypertensive feline models