Alcohols and polyols
- (1)
- (55)
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- (1)
- (65)
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- (395)
- (6)
- (102)
- (21)
- (50)
- (31)
- (61)
- (13)
- (14)
- (1)
- (2)
- (1)
- (26)
- (6)
- (4)
- (1)
- (6)
- (1)
- (462)
- (9)
- (46)
- (11)
- (45)
- (6)
- (1)
- (7)
- (10)
- (145)
- (114)
- (6)
- (5)
- (1)
- (1)
- (1)
- (1)
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- (1)
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- (7)
- (14)
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- (1)
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- (1)
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- (21)
- (5)
- (2)
- (2)
- (2)
- (16)
- (2)
- (30)
- (2)
- (4)
- (1)
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- (20)
- (10)
- (4)
- (15)
- (1)
- (4)
- (6)
- (2)
- (2)
- (2)
- (2)
- (4)
- (3)
- (1)
- (28)
- (29)
- (7)
- (3)
- (5)
- (1)
- (36)
- (5)
- (4)
- (2)
- (5)
- (4)
- (17)
- (15)
- (4)
- (5)
- (2)
- (5)
- (4)
- (33)
- (4)
- (2)
- (6)
- (8)
- (2)
- (2)
- (8)
- (7)
- (7)
- (2)
- (1)
- (26)
- (1)
- (1)
- (1)
- (2)
- (1)
- (3)
- (4)
- (3)
- (1)
- (15)
- (12)
- (1)
- (2)
- (2)
- (7)
- (12)
- (1)
- (14)
- (24)
- (1)
- (8)
- (4)
- (1)
- (2)
- (1)
- (17)
- (2)
- (6)
- (5)
- (2)
- (1)
- (5)
- (3)
- (4)
- (24)
- (5)
- (3)
- (5)
- (14)
- (1)
- (1)
- (1)
- (11)
- (3)
- (2)
- (4)
- (11)
- (2)
- (7)
- (4)
- (1)
- (1)
- (3)
- (6)
- (11)
- (5)
- (3)
- (1)
- (2)
- (11)
- (14)
- (7)
- (2)
- (2)
- (1)
- (3)
- (2)
- (10)
- (1)
- (2)
- (4)
- (4)
- (3)
- (1)
- (3)
- (5)
- (1)
- (1)
- (2)
- (10)
- (2)
- (2)
- (3)
- (7)
- (1)
- (5)
- (4)
- (1)
- (2)
- (9)
- (4)
- (2)
- (12)
- (4)
- (1)
- (1)
- (5)
- (3)
- (10)
- (2)
- (5)
- (1)
- (1)
- (1)
- (10)
- (5)
- (1)
- (2)
- (2)
- (6)
- (14)
- (2)
- (4)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
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- (2)
- (1)
- (1)
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- (2)
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- (1)
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- (1)
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- (9)
- (1)
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- (1)
- (1)
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- (3)
- (5)
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- (1)
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- (2)
- (2)
- (1)
- (4)
- (2)
- (1)
- (2)
- (2)
- (11)
- (9)
- (1)
- (1)
- (2)
- (1)
- (1)
- (3)
- (1)
- (1)
- (10)
- (1)
- (1)
- (1)
- (2)
- (4)
- (11)
- (1)
- (2)
- (4)
- (20)
- (21)
- (1)
- (2)
- (8)
- (2)
- (3)
- (3)
- (8)
- (4)
- (2)
- (1)
- (1)
- (3)
- (1)
- (2)
- (3)
- (2)
- (1)
- (2)
- (1)
- (1)
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- (1)
- (5)
- (12)
- (9)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (3)
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- (1)
- (1)
- (1)
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- (1)
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- (1)
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- (1)
- (1)
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- (1)
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- (5)
- (1)
- (2)
- (2)
- (1)
- (10)
- (4)
- (1)
- (9)
- (1)
- (8)
- (1)
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- (2)
- (5)
- (1)
- (1)
- (1)
- (1)
- (1)
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- (1)
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- (1)
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- (1)
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- (1)
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- (1)
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- (11)
- (82)
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- (81)
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- (378)
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- (1)
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Filtered Search Results
Medchemexpress LLC Topotecan hydrochloride | 119413-54-6 | MFCD00866235 | 99.9% | 457.91 | 100 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Topotecan hydrochloride is a potent Topoisomerase I inhibitor with significant antineoplastic activities. It is intended for research and analytical applications, playing a role in studies related to cancer, autophagy, and apoptosis.
- Potent Topoisomerase I inhibitor
- Demonstrates antineoplastic activities
- Inhibits the proliferation of human glioma cells
- Induces cell cycle arrest in G0/G1 and S phases
- Promotes apoptosis in various cell lines
- Store at 4°C, sealed, away from moisture and light
- Store in solvent at -80°C for 2 years or -20°C for 1 year
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Amiloride hydrochloride | 2016-88-8 | MFCD00211292 | 99.8% | 266.09 g/mol | C6H9Cl2N7O | 10 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Amiloride hydrochloride is the analytical reference standard of amiloride intended for research and analytical applications. It functions as an inhibitor of epithelial sodium channels (ENaC) and urokinase-type plasminogen activator receptor (uPA), and blocks polycystin-2 (PC2/TRPP2) channels.
- High purity analytical standard (99.8%).
- Suitable for assay development, calibration, and method validation.
- Available in small reference quantities for laboratory use, such as 10 mg.
- Solid powder form, stable under recommended storage conditions.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Ladostigil hydrochloride | 209394-18-3 | 99.9% | 308.80 g/mol | C16H21ClN2O2 | 50 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Ladostigil hydrochloride is the hydrochloride salt of ladostigil, an orally active dual inhibitor of cholinesterase and brain-selective monoamine oxidase. It exhibits neuroprotective, antioxidant, and anti-inflammatory properties and is used as a research reagent in studies of neurodegeneration, depression, and Alzheimer's disease.
- Dual cholinesterase and monoamine oxidase inhibitor
- Neuroprotective, antioxidant, and anti-inflammatory activity
- Hydrochloride salt for improved solubility
- Click-chemistry compatible (contains an alkyne group)
- High purity verified by RP-HPLC, suitable for research
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Viloxazine hydrochloride | 35604-67-2 | MFCD00661100 | 98.9% | 273.75 g/mol | C13H20ClNO3 | 10MM 1ML
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Viloxazine hydrochloride is a research-grade small-molecule norepinephrine transporter inhibitor supplied for in vitro pharmacology and biochemical assays. The product is available as solid and as a ready-to-use 10 mM solution in DMSO (1 mL), providing a convenient format for concentration-controlled experiments.
- Ready-to-use 10 mM solution in DMSO, 1 mL
- Also available as solid in multiple mg pack sizes
- High purity (98.9% typical)
- Molecular formula C13H20ClNO3 and molecular weight ~273.75 g/mol
- CAS number 35604-67-2 for unambiguous identification
- SDS and storage instructions provided for safe handling
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Medchemexpress LLC DC-BPi-11 hydrochloride | 97.0% | C20H24ClN5O2S | 1 ML
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DC-BPi-11 hydrochloride is an inhibitor of bromodomain PHD finger transcription factor (BPTF) with an IC50 of 698 nM. It significantly inhibits leukemia cell proliferation in human leukemia MV-4-11 cells (EC50 120 nM, IC50 0.89 μM). The compound decreases downstream oncogene expression and c-Myc protein levels, with minimal effects on normal cells. Intended for research use only.
- Inhibits bromodomain PHD finger transcription factor (BPTF)
- IC50 of 698 nM against BPTF
- Inhibits leukemia cell proliferation
- Decreases oncogene expression and c-Myc protein
- Minimal effects on normal cells
- Off-white to light yellow solid appearance
- Molecular weight: 433.95
- Chemical formula: C20H24ClN5O2S
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Medchemexpress LLC CCG258208 hydrochloride | 98.1% | 488.94 | 1 MG
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CCG258208 (GRK2-IN-1) hydrochloride is a potent and selective GRK2 (G protein-coupled receptor kinase 2) inhibitor (IC50=30 nM). It exhibits 230-fold selectivity over GRK5 and more than 2500-fold selectivity over GRK1, PKA, and ROCK1. This compound can be utilized in heart failure research.
- Potent and selective GRK2 inhibitor (IC50=30 nM).
- Exhibits 230-fold selectivity over GRK5 (IC50=7.09 μM) and more than 2500-fold selectivity over GRK1 (IC50=87.3 μM), PKA, and ROCK1.
- Applicable in heart failure research.
- Significant improvement in βAR-stimulated contractility in mouse cardiomyocytes at concentrations as low as 0.1 μM.
- Superior half-life in vivo with total plasma drug levels exceeding the GRK2 IC50 for seven hours after a single intraperitoneal administration of 10 mg/kg in CD-1 mice.
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Medchemexpress LLC Gefitinib hydrochloride | 184475-55-6 | 99.8% | 500 MG
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Gefitinib hydrochloride (ZD1839 hydrochloride) is a potent, selective, and orally active inhibitor of EGFR tyrosine kinase, with an IC50 of 33 nM. It specifically inhibits EGF-stimulated tumor cell growth with an IC50 of 54 nM and blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Additionally, Gefitinib hydrochloride has been shown to induce autophagy and possesses antitumour activity.
- Potent, selective, and orally active EGFR tyrosine kinase inhibitor.
- Inhibits EGF-stimulated tumor cell growth.
- Blocks EGF-stimulated EGFR autophosphorylation in tumor cells.
- Induces autophagy.
- Demonstrates antitumour activity.
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Medchemexpress LLC Tocainide hydrochloride | 71395-14-7 | 99.5% | 1 ML
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Tocainide hydrochloride is a sodium channel blocker that blocks sodium channels in pain-producing foci in nerve membranes. It is a primary amine analog of lidocaine and can be used for the treatment of tinnitus.
- Suppresses ventricular ectopic activity.
- Suitable for laboratory centrifugation and storage.
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Medchemexpress LLC Sri-37330 hydrochloride | 2322245-49-6 | 99.7% | C16H20ClF3N4O2S | 250 MG
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SRI-37330 hydrochloride is an orally bioavailable thioredoxin-interacting protein (TXNIP) inhibitor. It inhibits glucagon secretion and function, reduces hepatic glucose production, and reverses hepatic steatosis. It can be used for type 2 diabetes research.
- Inhibits activity of human TXNIP promoter in INS-1 cells.
- Inhibits mRNA and protein levels of TXNIP.
- Inhibits polymerase II (Pol II) binding to the E-box motif region of the TXNIP promoter.
- Lowers glucagon secretion in TC1-6 cells.
- Inhibits glucagon-induced glucose output from primary hepatocytes.
- Decreases glucagon secretion and blocks hepatic glucose output in mice.
- Reverses obesity- and STZ-induced diabetes and hepatic steatosis in mice.
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Medchemexpress LLC BMY-25368 hydrochloride | 86134-36-3 | ≥97.0% | 379.88 | C19H26ClN3O3 | 10 MG
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BMY-25368 hydrochloride is a research reagent used as a histamine H2 receptor antagonist and gastric acid secretion inhibitor. Supplied as a hydrochloride salt with documented molecular and purity data, it is intended for preclinical in vitro and in vivo studies where receptor antagonism or gastric secretion modulation is required.
- Histamine H2 receptor antagonist for gastric acid secretion studies.
- Hydrochloride salt form for improved solubility and stability.
- High purity (≥97.0% by NMR) suitable for research use.
- Verified molecular weight (379.88) and formula for accurate dosing.
- Available in small-scale quantities for preclinical experiments.
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Medchemexpress LLC Flavoxate hydrochloride | 3717-88-2 | 99.7% | 1 ML
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Flavoxate hydrochloride | 3717-88-2 | 99.7% | 1 ML
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Medchemexpress LLC DC-BPi-11 hydrochloride | 00-00-0 | 97.0% | C20H24ClN5O2S | 10MG
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DC-BPi-11 hydrochloride is a research-grade small-molecule inhibitor of the bromodomain PHD finger transcription factor (BPTF) used in epigenetics and cancer research. It has demonstrated inhibition of leukemia cell proliferation and a reported IC50 of 698 nM against BPTF. The compound is supplied as a powder and analytical batch documentation reports a purity of 97.0%.
- Inhibits BPTF with an IC50 of 698 nM.
- Demonstrates inhibition of leukemia cell proliferation.
- Supplied as a powder for handling and storage flexibility.
- Powder stable at -20°C for up to 3 years.
- High reported purity: 97.0%.
- Chemical formula C20H24ClN5O2S; molecular weight 433.95.
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Medchemexpress LLC Gyki 53655 (hydrochloride) | 143692-48-2 | MFCD01941362 | 98.4% | 388.85 g·mol⁻¹ | C19H21ClN4O3 | 1 ML
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GYKI 53655 hydrochloride is a selective, non-competitive antagonist of AMPA receptors used in electrophysiology and receptor pharmacology research. The hydrochloride salt is available as a high-purity solid or as a ready-to-use 10 mM solution in DMSO.
- Selective non-competitive AMPA and kainate receptor antagonist.
- Available as 10 mM solution in DMSO (1 mL) or as solid doses.
- High purity (~98.4%) suitable for in vitro studies.
- Molecular weight 388.85 g·mol⁻¹ and formula C19H21ClN4O3.
- Recommended storage: solid at 4°C; solution at -80°C for long-term storage.
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Medchemexpress LLC Defactinib hydrochloride | 1073160-26-5 | 99.4% | 50 MG
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Defactinib hydrochloride is the hydrochloride salt of defactinib (VS-6063; PF-04554878), a small-molecule focal adhesion kinase (FAK) inhibitor used in research to study FAK signaling, tumor cell motility, and antineoplastic and antiangiogenic mechanisms.
- Inhibits FAK phosphorylation at Tyr397 in a time- and dose-dependent manner.
- Hydrochloride salt form, off-white powder suitable for research use.
- Molecular formula C20H22ClF3N8O3S; molecular weight 546.95 g/mol.
- Reported purity 99.35% with available certificate of analysis.
- Available in multiple pack sizes, including 50 mg.
- Supporting documents available: data sheet, COA, and SDS.
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Medchemexpress LLC Tiagabine (hydrochloride) | 145821-59-6 | MFCD00892911 | ≥98% | 1 ML
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Tiagabine (hydrochloride) is an anticonvulsant agent and a selective inhibitor of the GAT-1 GABA transporter. It potently and selectively inhibits GABA reuptake and demonstrates neuroprotective properties.
- Selective inhibitor of GAT-1 GABA transporter
- Potently and selectively inhibits GABA reuptake
- Exhibits neuroprotective properties
- Protects neurons against mutant huntingtin-induced toxicity
- Increases viability of SH-SY5Y cells
- Inhibits GABA uptake in mouse GAT1 expressed in HEK293 cells
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