Sulfoxides
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Cell Signaling Technology DL-alpha-Difluoromethylornithine Hydrochloride (DFMO) 10 mg
DL-alpha-Difluoromethylornithine Hydrochloride (DFMO) 10 mg
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Medchemexpress LLC CB2R/FAAH modulator-3 | 2876918-67-9 | C22H31NO2 | 100 MG
CB2R/FAAH modulator-3 (compound 27) is a dual-targeting modulator that acts as a CB2R agonist and FAAH inhibitor. It has Ki values of 20.1 nM for CB2R and 67.6 nM for CB1R, and an IC50 value of 3.4 μM for FAAH.
- Dual-targeting modulator
- Acts as a CB2R agonist
- Acts as a FAAH inhibitor
- Can be used in studies related to cancer
- Can be used in studies related to deleterious inflammatory cascades occurring in neurodegenerative diseases
- Can be used in studies related to COVID-19 infection
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Medchemexpress LLC CXCR7 modulator 2 | 2227426-37-9 | 98.7% | 522.68 | 50 MG
CXCR7 modulator 2 is a C-X-C Chemokine Receptor Type 7 (CXCR7) modulator with a Ki of 13 nM. It is intended for research use only.
- Potent CXCR7-binding affinity (Ki=13 nM)
- Demonstrates β-arrestin activity (EC50=11 nM)
- Improved selectivity in GPCR panel
- Improved therapeutic index in hERG patch-clamp assay
- Moderate to high in vitro turnover in mouse-liver microsomes and hepatocytes
- Good aqueous solubility
- Significantly reduced cardiac fibrosis in isoproterenol-induced cardiac injury model in mice
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Medchemexpress LLC Kv3.1 modulator 2 | 99.8% | 437.88 | 50 MG
Kv3.1 modulator 2 (compound 4) is a Kv3.1 channels modulator with an EC50 value of 68 nM. This modulator is suitable for laboratory research and studies involving Kv3.1 channels.
- Functions as a Kv3.1 channels modulator
- Has an EC50 value of 68 nM
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