Sulfoxides
Medchemexpress LLC CRBN modulator-1 | 2407829-65-4 | 98.0% | 324.29 | 25 MG
CRBN modulator-1 is a Thalidomide analog and a CRBN modulator, extracted from WO2020006262A1, compound 10. It has an IC₅₀ of 3.5 μM and a Kᵢ of 0.98 μM. This product is for research use only.
- Thalidomide analog and CRBN modulator.
- IC₅₀ of 3.5 μM.
- Kᵢ of 0.98 μM.
- For research use only.
Medchemexpress LLC Cytochrome P450 17A1 Antibody (YA478) | 57 kDa | 100 UL
The Cytochrome P450 17A1 Antibody (YA478) from MedChemExpress is a rabbit-derived monoclonal antibody identified for laboratory research. Supplied as a liquid, it is stable under recommended storage conditions and formulated with TBS, BSA, glycerol, and sodium azide. This antibody is suitable for detecting Cytochrome P450 17A1 in human, mouse, and rat samples.
- Predicted and observed band size of 57 kDa
- Suitable for Western blot (WB), immunocytochemistry/immunofluorescence (ICC/IF), immunohistochemistry-paraffin (IHC-P), and flow cytometry (FC)
- Supplied at a concentration of 1.0 mg/mL
- Store at -20°C for up to 1 year
- Shipped with blue ice
Medchemexpress LLC N-(4-(4-(2-methoxyethoxy)phenyl)thiazol-2-yl)isoxazole-5-carboxamide | 2375779-31-8 | 99.3% | 345.37 g/mol | C16H15N3O4S | 10 MG
GP130 modulator-1 (compound A33) is a small-molecule modulator of the gp130 signaling pathway intended for research use in studies of inflammatory and degenerative disorders.
- Small-molecule gp130 signaling pathway modulator for research use.
- High purity: 99.3%.
- Molecular weight 345.37 g/mol.
- Chemical formula C16H15N3O4S.
- Available in multiple pack sizes, including 10 mg.
- Supplied as a light yellow to yellow solid for laboratory handling and storage.
TARGETMOL CHEMICALS INC SULINDAC SULFIDE 10MG
Also available in 25 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Sulindac sulfide (cis-Sulindac sulfide) is a non-steroidal anti-inflammatory compound that has a high affinity for COX-1 and acts as an inhibitor in Ras activation of Raf-1. Sulindac sulfide is a non-competitive inhibitor of gamma-secretase with an IC50 value of 20.2 uM. It is an active metabolite of sulinic acid. purity: 99%
Medchemexpress LLC 3',4'-Tetramethylene-α-pyrrolidinobutiophenone (hydrochloride) | 2749504-65-0 | 99.9% | 307.86 | 50 MG
3',4'-Tetramethylene-α-pyrrolidinobutiophenone hydrochloride is structurally categorized as a drug derivative.
- Applications: Neuroscience-Neuromodulation
- Research area: Neurological disease
- Target: Drug derivative
Medchemexpress LLC Triclabendazole sulfoxide | 100648-13-3 | 98.78% | 375.66 | 50 MG
Triclabendazole sulfoxide (TCBZ-SO) is the main plasma metabolite of Triclabendazole and exhibits anti-parasite effects. It can also inhibit the membrane transporter ABCG2/BCRP.
- Exhibits anti-parasite effects.
- Can inhibit membrane transporter ABCG2/BCRP.
- Available in different quantities to suit research needs.
- Purity of 98.78%.
- Multiple related antibodies and small molecules are also listed, indicating its use in various research areas such as anti-infection, membrane transporter/ion channel, protein tyrosine kinase/RTK, and parasitic infection.
eMolecules 1600-44-8 | Tetramethylene sulfoxide | MFCD00005477 | 25g
Medchem Express | Alogabat | 5mg | 686240419 | HY-132806 | 2230009-48-8 | 409.446 | C21H23N5O4
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![Medchemexpress LLC 2-Quinoxalinecarboxamide, N-[2-[3-[(4-amino-1-piperidinyl)methyl]imidazo[2,1-b]thiazol-6-yl]phenyl]- | 925437-38-3 | 96.2% | 483.59 | 500 UG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000385638-logo.png-250.jpg){kind=logo}
Medchemexpress LLC 2-Quinoxalinecarboxamide, N-[2-[3-[(4-amino-1-piperidinyl)methyl]imidazo[2,1-b]thiazol-6-yl]phenyl]- | 925437-38-3 | 96.2% | 483.59 | 500 UG
Sirtuin modulator 8 is a sirtuin modulator that can activate Sirtuin activity. It significantly downregulates the expression of monocyte chemoattractant protein-1 (MCP-1) and upregulates the expression of fibroblast growth factor 21 (FGF21). This modulator regulates the expression of inflammation- and metabolism-related genes, showing potential for studying metabolic diseases and inflammatory diseases. It also causes a significant decrease in MCP-1 expression in a human leukocyte (WBC) model, indicating its potential to inhibit inflammatory responses.
- Activates sirtuin activity.
- Downregulates MCP-1 expression.
- Upregulates FGF21 expression.
- Shows potential for studying metabolic diseases.
- Shows potential for studying inflammatory diseases.