Cinnamic acids and derivatives
Medchemexpress LLC Entacapone | 130929-57-6 | MFCD00866580 | 99.2% | 305.29 g/mol | C14H15N3O5 | 5 MG
Entacapone (Standard) is an analytical reference standard of entacapone provided for research and analytical use. Supplied in small quantitative sizes suitable for assay development, method validation, and quality control, the product includes batch documentation and a Certificate of Analysis reporting high purity. It is used as a reference material in studies involving COMT inhibition and related biochemical assays.
- Analytical standard for assay development and method validation.
- Available in small sizes, including a 5 mg vial.
- Certified purity approximately 99.2% (COA available).
- Useful for quality control and reference material applications.
- Molecular formula C14H15N3O5; molecular weight 305.29 g/mol.
Apexbio Technology LLC Tyrphostin AG 1296 146535-11-7 10mM (in 1mL DMSO)
Tyrphostin AG 1296 (CAS 146535-11-7) is a selective inhibitor of platelet-derived growth factor receptor (PDGFR) kinase via ATP-competitive binding Its inhibitory activity (IC50 0 3 0 5 M) results from inducing conformational changes in the ATP-binding domain of PDGFR blocking receptor autophosphorylation induced by ligand binding In vitro studies demonstrate inhibition of PDGF-stimulated mitogenesis (IC50 1 5 M) and cell proliferation (IC50 3 2 M) using Swiss 3T3 cells without significant effects on EGF receptor signaling at concentrations up to 100 M Tyrphostin AG 1296 serves as a research tool for investigating PDGFR-mediated signaling pathways
TARGETMOL CHEMICALS INC POLYINOSINIC-POLYCYTIDYL 25MG
Also available in 5 mg 10 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. Polyinosinic-polycytidylic acid (Poly(IC)) is a synthetic double-stranded RNA (dsRNA) analog and is an immunostimulant that acts as the most potent interferon (IFN) inducer. It also is a Toll-like receptor- 3 (TLR3) agonist. purity: 98%
Med Vet International Fluoxetine Capsules (Prozac), 20mg, 100ct
VET LICENSE NEEDS TO BE PROVIDED IN 3-4 BUSINESS DAYS OR ORDER WILL BE CANCELLED
Fluoxetine is a generic form of PROZac and is an SSRI antidepressant. It affects chemicals in the brain that may be unbalanced in people with depression, panic, anxiety, or obsessive-compulsive disorder.
Apexbio Technology LLC Entacapone 130929-57-6 100mg
Entacapone (CAS 130929-57-6) is a selective second-generation inhibitor of catechol-O-methyltransferase (COMT) It demonstrates potent inhibition of total COMT in mouse liver with reported IC50 and Ki values of 20 1 nM and 10 7 nM respectively In rat models IC50 values for soluble COMT and membrane-bound COMT are 14 3 nM and 73 3 nM Entacapone is primarily utilized in research as an adjunct to levodopa and dopa decarboxylase inhibitor regimens in Parkinson s disease studies given its ability to suppress the formation of 3-O-methyldopa thereby enhancing levodopa bioavailability and prolonging its pharmacological effect
Sigma Aldrich Fine Chemicals Biosciences Rivaroxaban R enantiomer U20MG
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Medchemexpress LLC SAR405 R enantiomer | 1946010-79-2 | 99.9% | 443.85 | C19H21ClF3N5O2 | 10MG
SAR405 R enantiomer is the less active stereoisomer of the PIK3C3/Vps34 inhibitor SAR405, provided as a solid for in vitro research use only. It is suited for comparative pharmacology and control studies and includes handling and storage guidance for reliable experimental use.
- Less active enantiomer used as a comparative control in assays.
- High purity (≈99.9%).
- Solid, white to off-white appearance.
- Molecular formula C19H21ClF3N5O2; molecular weight 443.85.
- Soluble in DMSO at 100 mg/mL; ultrasonic assistance recommended.
- Store powder at -20°C for long-term stability; store solutions at -80°C.
- Intended for laboratory research use only.
Medchemexpress LLC m-Coumaric acid (Standard) | 588-30-7 | 99.9% | 164.16 | 100 MG
m-Coumaric acid (Standard) | 588-30-7 | 99.9% | 164.16 | 100 MG
Medchemexpress LLC Cinnamic acid | 621-82-9 | MFCD00004369 | 148.16 | 500 MG
Cinnamic acid is a chemical compound with potential applications in cancer intervention. It has shown dose-dependent growth inhibition in various tumor cells, including glioblastoma, melanoma, prostate, and lung carcinoma cells, with IC50 values ranging from 1 to 4.5 mM.
- Potential use in cancer intervention.
- Exhibits dose-dependent growth inhibition in tumor cells.
- Induces morphological changes consistent with melanocyte differentiation.
- Causes a dose-dependent loss of invasive capacity in treated tumor lines.
- Effective in glioblastoma, melanoma, prostate, and lung carcinoma cells.
Medchemexpress LLC 4-chlorocinnamic acid | 1615-02-7 | MFCD00004396 | 99.0% | 182.61 g·mol⁻1 | C9H7ClO2 | 10g
4-Chlorocinnamic acid is a derivative of Cinnamic acid (HY-N0610A) 4-Chlorocinnamic acid inhibits the monophenolase and diphenolase activities of mushroom tyrosinase with IC50 values of 0 477 mM and 0 229 mM respectively 4-Chlorocinnamic acid inhibits the mycelial growth of Colletotrichum gloeosporioides 4-Chlorocinnamic acid exhibits anticonvulsant activity against acute epilepsy induced by pentylenetetrazol[1][2][3][4]
Chem-Impex International, Inc. trans-4-Bromocinnamic acid | MFCD00004394 | 25G
trans-4-Bromocinnamic acid, MFCD00004394, 25G