Coumarins and derivatives
Medchemexpress LLC 4-Hydroxycoumarin | 1076-38-6 | MFCD00006856 | 10MM 1ML
4-Hydroxycoumarin | 1076-38-6 | MFCD00006856 | 10MM 1ML
Cayman Chemical 7-Acetoxy-4-methylcoumarIn 5g
A fluorogenic substrate for carboxylesterase and AChE; upon hydrolysis by carboxylic esterase or AChE, 4-MU is released, which displays pH-dependent excitation maxima of 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4, respectively, and an emission maximum between 445-454 nm; has been used to detect the presence of carboxylesterases in isolated human lung tissue
SIGMA ALDRICH FINE CHEMICALS BIOSCIENCES 7-METHOXYCOUMARIN-4-ACETYL-GL
NC3736128 7-METHOXYCOUMARIN-4-ACETYL-GL
Medchemexpress LLC Coumarin 106 | 41175-45-5 | MFCD00041949 | >98.0% | 281.35 | C18H19NO2 | 50 MG
Coumarin 106 is a dipolar laser dye used in research that also functions as a cholinesterase inhibitor. It exhibits mixed-type inhibition of acetylcholinesterase (reported pIC50 4.97, Ki 2.36 μM) and lower potency against butyrylcholinesterase (pIC50 4.56). Molecular formula C18H19NO2 and molecular weight 281.35. In vitro data report no toxicity in Caco-2 cells.
- Dipolar laser dye useful for fluorescence and photonic applications.
- Inhibits acetylcholinesterase with reported pIC50 4.97 and Ki 2.36 μM.
- Also inhibits butyrylcholinesterase with pIC50 4.56.
- Molecular weight 281.35 and formula C18H19NO2.
- Reported non-toxic in Caco-2 cell assays.
- Supplied as a 50 mg research reagent.
Medchemexpress LLC 4-Ethoxycoumarin | 35817-27-7 | 99.9% | 190.20 | 1 G
4-Ethoxycoumarin is an antimicrobial compound with a molecular weight of 190.20 and a purity of 99.9%. It is typically supplied as a solid, appearing white to off-white in color. This product is intended strictly for research use.
- Antimicrobial properties
- For research use only
- Solid, white to off-white appearance
Medchemexpress LLC Coumarin 6 | 38215-36-0 | 1 ML
Coumarin 6 is a fluorescent dye utilized as a fluorescent probe within microparticle drug delivery systems. It is employed to conduct in vivo tracking, cellular uptake studies, and investigations into the transport mechanisms of drug delivery systems. It has an excitation wavelength (λexc) of 450 nm and an emission wavelength (λem) of 505 nm. This product is intended for research use only and is not sold to patients.
- Used for in vivo tracking, cell uptake, and transport mechanism studies in drug delivery systems
- Optimal wavelengths: Excitation at 450 nm and emission at 505 nm
- Purity: 99.59%
Medchemexpress LLC 7-Methylcoumarin | 2445-83-2 | MFCD00006880 | 5 G
7-Methylcoumarin is a coumarin derivative known for its potent hepatoprotective and antioxidant properties. It functions as a mechanism-based inhibitor for CYP2A6, a key enzyme involved in drug metabolism. Studies have shown that it can significantly reduce markers of liver damage, such as alanine aminotransferase (ALT), aspartate aminotransferase (AST), and serum bilirubin (TB), in models of CCl4-induced liver injury. Additionally, it helps to restore total protein (TP) and albumin (TA) levels and prevent oxidative stress. It also exhibits an ability to decrease the mitotic activity of *A. sativum* promeristem.
- Possesses potent hepatoprotective properties
- Acts as a mechanism-based inhibitor for CYP2A6
- Reduces markers of liver damage
- Restores protein and albumin levels in serum
- Prevents oxidative stress
- Decreases mitotic activity
Medchemexpress LLC Coumarin | 91-64-5 | 146.15 | 500 MG
Coumarin is a potent and orally active anti-inflammatory agent. It demonstrates an antinociceptive effect, as well as antibacterial, antifungal, and anticancer activities.
- Potent and orally active anti-inflammatory agent.
- Shows an antinociceptive effect.
- Exhibits antibacterial activity.
- Exhibits antifungal activity.
- Exhibits anticancer activity.
Medchemexpress LLC Coumarin | 91-64-5 | 146.15 | 5 G
Coumarin is a potent and orally active anti-inflammatory agent. It also demonstrates antinociceptive, antibacterial, antifungal, and anticancer activities.
- Potent and orally active anti-inflammatory agent
- Shows antinociceptive effect
- Shows antibacterial, antifungal and anticancer activity
Medchemexpress LLC 7-Ethoxy-4-methylcoumarin | 87-05-8 | 99.44% | 50 G
7-Ethoxy-4-methylcoumarin is a coumarin derivative that functions as a substrate probe for mammalian cytochromes P450 1A1, 2B4, and 2B6.
- Coumarin derivative
- Substrate probe of mammalian cytochromes P450 1A1, 2B4 and 2B6
- Molecular weight: 204.22
- Formula: C12H12O3
- Appearance: Solid
- Color: White to off-white
- SMILES: O=C1C=C(C)C2=CC=C(OCC)C=C2O1
Medchemexpress LLC Coumarin-6-sulfonyl chloride | 10543-42-7 | 95.0% | 100 MG
Coumarin-6-sulfonyl chloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
- Biochemical reagent
- Used as a biological material
- Used as an organic compound for life science related research
Medchemexpress LLC 6-Hydroxycoumarin | 6093-68-1 | 10 G
6-Hydroxycoumarin is a coumarin exhibiting diverse biological activities. It is noted for its anti-inflammatory, anti-pyretic, anti-oxidant, and vasodilator properties. This compound also demonstrates anti-amoebic, anti-bacterial, anti-fungal, bacteriostatic, and antitumor activities.
- Demonstrates anti-inflammatory, anti-pyretic, and anti-oxidant activities
- Acts as a vasodilator, anti-amoebic, anti-bacterial, and anti-fungal agent
- Exhibits bacteriostatic and antitumor properties
- Appearance: light yellow to light brown solid
- Molecular formula: C9H6O3
- Molecular weight: 162.14
- Purity: 99.32%
- Melting point: 249-253 °C
- Boiling point: 248.82 °C at 760 mmHg