Flavonoids
Medchemexpress LLC 6-hydroxyflavanone | 4250-77-5 | MFCD00017485 | 99.9% | 240.25 g/mol | C15H12O3 | 1 G
6-Hydroxyflavanone is a naturally occurring flavanone used as a research chemical with reported activity against cyclooxygenase-2 (COX-2), 5-lipoxygenase (5-LOX), and opioid and GABA-A receptors; it is employed in studies of inflammation, neuropathic pain, and diabetes research.
- High purity (99.87%) suitable for analytical and biological studies.
- Chemical formula C15H12O3; molecular weight 240.25 g/mol.
- Available as a powder for convenient storage and handling.
- Targets COX-2, 5-LOX, opioid receptors, and GABA-A receptors in assays.
- Reported applications include inflammation, neuropathic pain, and diabetes research.
- Storage recommendations: powder at -20°C (long term) or 4°C (short term).
- For research use only; not for human or veterinary applications.
Apexbio Technology LLC AST 487 630124-46-8 50mg
AST487 (CAS 630124-46-8) is a small molecule inhibitor primarily targeting RET kinase exhibiting an IC50 of 0 88 M As a member of the N N -diphenylurea class AST487 inhibits RET autophosphorylation and attenuates downstream signaling pathways such as PLC and ERK in a dose-dependent manner It also displays inhibitory activity against additional kinases including KDR Flt-3 and c-Kit In cellular models harboring RET activating mutations (e g C634W) AST487 suppresses RET-mediated signaling and reduces proliferation of thyroid carcinoma cells with RET mutations In xenograft mouse models oral administration of AST487 leads to a notable reduction in tumor volume making it valuable for preclinical studies of RET-driven cancers
Medchemexpress LLC AMG 487 (S-enantiomer) | 473720-30-8 | C32H28F3N5O4 | 25 MG
AMG 487 S-enantiomer is the S enantiomer of AMG 487. It functions as an antagonist of the chemokine receptor CXCR3, targeting the GPCR/G Protein and Immunology/Inflammation pathways.
- Purity: 99.94%
- Appearance: Off-white to light yellow solid
- Storage (powder): -20°C for 3 years, 4°C for 2 years
- Storage (in solvent): -80°C for 2 years, -20°C for 1 year
- In vitro solubility: 100 mg/mL in DMSO
Medchemexpress LLC Naringenin chalcone | 73692-50-9 | 5 MG
Naringenin chalcone is an orally active intermediate involved in flavonol biosynthesis. It induces apoptosis, inhibits the production of MCP-1 and NO, and exhibits anticancer activity against glioblastoma. It also possesses anti-inflammatory and anti-allergic properties.
- Intermediate in flavonol biosynthesis
- Induces apoptosis
- Inhibits production of MCP-1 and NO
- Exhibits anticancer activity against glioblastoma
- Possesses anti-inflammatory properties
- Possesses anti-allergic properties
Medchemexpress LLC AMG 487 | 473719-41-4 | C32H28F3N5O4 | 1 ML
AMG 487 is an orally active and selective antagonist of CXC chemokine receptor 3 (CXCR3), inhibiting the binding of CXCL10 and CXCL11 to CXCR3 with IC50s of 8.0 and 8.2 nM, respectively. It is intended for research use only.
- Orally active and selective CXCR3 antagonist
- Inhibits CXCL10 and CXCL11 binding to CXCR3
- Purity of 99.89%
- Molecular weight of 603.59
- White to yellow solid appearance
- Inhibits CXCR3-mediated cell migration
- Inhibits calcium mobilization
![Medchemexpress LLC N-[(1S)-1-[3-(4-ethoxyphenyl)-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-N-(3-pyridinylmethyl | 473720-30-8 | 99.9% | 603.59 g/mol | C32H28F3N5O4 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000286210.png-250.jpg)
Medchemexpress LLC N-[(1S)-1-[3-(4-ethoxyphenyl)-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-N-(3-pyridinylmethyl | 473720-30-8 | 99.9% | 603.59 g/mol | C32H28F3N5O4 | 10 MG
AMG 487 (S-enantiomer) is the S enantiomer of AMG 487, a small-molecule antagonist of the CXC chemokine receptor 3 (CXCR3) supplied for research use. The compound is provided as a solid and is characterized by a defined chemical formula, molecular weight, CAS registry number, high purity, and recommended storage conditions.
- S enantiomer of a selective CXCR3 antagonist.
- High purity (99.94%).
- Chemical formula C32H28F3N5O4.
- Molecular weight 603.59 g/mol.
- CAS number 473720-30-8.
- Off-white to light yellow solid appearance.
- Recommended storage: powder -20 °C (3 years) or 4 °C (2 years); in solvent -80 °C (2 years) or -20 °C (1 year).
TARGETMOL CHEMICALS INC HARMOL 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Harmol (Methylpyridoindolol) is a (beta)-carboline isolated from nature. purity: 98%
Medchemexpress LLC 4'-Hydroxyflavanone | 6515-37-3 | 1 ML
4'-Hydroxyflavanone is an inhibitor of SREBP maturation and lipid synthesis, and a synthetic analogue of flavanone. It is used in research into hepatic steatosis and dyslipidemia.
- Purity of 99.75%
- Molecular weight of 240.25 g/mol
- Chemical formula C15H12O3
- Classified as a flavonoid, flavanone, phenol, and monophenol
- Isolated from Aspergillus niger
- Provided as a 10 mM solution in DMSO
- Store powder at -20°C for 3 years, or 4°C for 2 years
- Store solution at -80°C for 6 months, or -20°C for 1 month
![Medchemexpress LLC 5-hydroxy-3-[(2-hydroxyphenyl)methyl]-7-(2-methylnonan-2-yl)chromen-2-one | 1399049-81-0 | 98.0% | 408.53 g/mol | C26H32O4 | 5MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000238692.png-250.jpg)
Medchemexpress LLC 5-hydroxy-3-[(2-hydroxyphenyl)methyl]-7-(2-methylnonan-2-yl)chromen-2-one | 1399049-81-0 | 98.0% | 408.53 g/mol | C26H32O4 | 5MG
PSB-SB-487 is a small-molecule research compound that functions as a potent GPR55 antagonist and a CB2 receptor agonist. It is intended for research use only and is employed in studies of metabolic disorders, neurodegeneration, pain mechanisms, and oncology. Reported potency includes a GPR55 IC50 of 0.113 μM and a human CB2 Ki of 0.292 μM.
- Potent GPR55 antagonist and CB2 agonist with reported potency values.
- Molecular formula C26H32O4; molecular weight 408.53 g/mol.
- High purity: 98.0%.
- Appearance: white to off-white solid.
- Recommended storage: powder at -20°C for long term, 4°C for short term; in solvent at -80°C.
- Supplied in small milligram quantities suitable for in vitro research and pharmacology.
Selleck Chemical LLC AMG 487
AMG 487 is an orally active and selective CXC chemokine receptor 3 (CXCR3) antagonist that inhibits the binding of IP-10 (CXCL10) and ITAC (CXCL11) to CXCR3 with IC50 of 8 0 nM and 8 2 nM respectively
Crescent Chemical Co Inc NAPHTHOL-AS-MX-PHOSPHATE
Naphthol-AS-MX-phosphate research grade Selective substrate of alkaline phosphatase. Suitable for dye coupling. Fast Blue RR (1). Fast Red TR-salt (cat. no. 21317) (2). Size - 250MG Storage Conditions - -15 °C TO -25 °C Catalog Number - 30002.01 CAS No.
Indofine Chemical Naringenin, 98.2%, 5 Gm
Moelcular Formula: C15H12O5, Purity: 98%, Molecular Weight: 272.26, Appearance: Brown crystalline powder, Solubility: Soluble in alcohol, ether, benzene, Storage conditions: Store in a cool, dry place, Also known as 5,7,4'-Trihydroxyflavanone; 2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
Selleck Chemical LLC AMG 487
AMG 487 is an orally active and selective CXC chemokine receptor 3 (CXCR3) antagonist that inhibits the binding of IP-10 (CXCL10) and ITAC (CXCL11) to CXCR3 with IC50 of 8 0 nM and 8 2 nM respectively
Medchemexpress LLC Flavanone | 487-26-3 | 500 MG
Flavanone is a naturally occurring flavone with inhibitory activity for human estrogen synthetase (aromatase). It acts as an inhibitor for the ERK/p38/NF-κB signaling pathway and exhibits oral activity and antitumor efficacy.
- Naturally occurring flavone.
- Inhibits human estrogen synthetase (aromatase).
- Inhibits the ERK/p38/NF-κB signaling pathway.
- Exhibits oral activity.
- Shows antitumor efficacy.
eMolecules 6515-36-2 | 7-Hydroxyflavanone | Combi-Blocks, Inc. | MFCD00017487 | 240.258 | C15H12O3 | 98.000 | Oc1ccc2C(=O)CC(Oc2c1)c1ccccc1 | 5g | 603145398
7-Hydroxyflavanone | Combi-Blocks, Inc. | 6515-36-2 | MFCD00017487 | 240.258 | C15H12O3 | 98.000 | Oc1ccc2C(=O)CC(Oc2c1)c1ccccc1 | 5g | 603145398