Phenols
BIOHIPPO h/m ACSL4-sh-RFP/Luc
h/m ACSL4-sh-RFP/Luc shRNA lentiviral vector expressing RFP/Luc with selection for studies in Human/Mouse Each vial provides a nominal titer of 2x10E6 transducing units TU Validated h/m ACSL4 shRNA Lentivirus High-titer shRNA lentiviral particles specific for human/mouse acyl-CoA synthetase long chain family member 4 (ACSL4) The shRNA has been validated to meet or exceed 70% knockdown of ACSL4 using a specific fluorescence-based method that is more rapid and reliable than qPCR The lentiviral particles are ultra-purified and concentrated by PEG precipitation and sucrose gradient centrifugation and are ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
Medchemexpress LLC H-151 | 941987-60-6 | 99.86% | 279.34 | 1 ML
H-151 is a potent, selective and covalent antagonist of STING that has noteworthy inhibitory activity both in cells and in vivo. H-151 reduces TBK1 phosphorylation and suppresses STING palmitoylation. It can be used for the research of autoinflammatory disease.
- Potent, selective, and covalent antagonist of STING.
- Exhibits noteworthy inhibitory activity in cells and in vivo.
- Reduces TBK1 phosphorylation.
- Suppresses STING palmitoylation.
- Useful for research of autoinflammatory disease.
- Reduces IFNβ luciferase reporter measurements.
- Inhibits phosphorylation of TBK1.
- Suppresses palmitoylation.
- Markedly reduces systemic cytokine responses.
- Exhibits notable efficacy in certain mouse models.
- Reaches effective systemic levels.
- Displays a short half-life in serum.
- Forms an adduct to mmSTING.
TARGETMOL CHEMICALS INC BC-1471 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. BC-1471 is a STAM-binding protein (STAMBP) deubiquitinase inhibitor. BC-1471 inhibits inflammasome activity of NALP7 (NACHT LRR and PYD domains-containing protein 7) [1]. purity: 98%
Medchemexpress LLC Sotalol hydrochloride | 959-24-0 | 99.9% | 500 MG
Sotalol hydrochloride is an orally active, non-selective β-adrenergic receptor blocker. It is a potent antiarrhythmic agent used for the research of pediatric arrhythmias. This compound blocks β-receptors and potassium KCNH2 channels, and acts as an antiepileptic agent.
- Orally active
- Non-selective β-adrenergic receptor blocker
- Potent antiarrhythmic agent
- Used for the research of pediatric arrhythmias
- Blocks β-receptors
- Blocks potassium KCNH2 channels
- Acts as an antiepileptic agent
Medchemexpress LLC Pilocarpine hydrochloride | 54-71-7 | 99.98% | 5 G
Pilocarpine Hydrochloride is a potent M3-type muscarinic acetylcholine receptor (M3 muscarinic receptor) agonist. It is intended for research use only.
- Potent M3-type muscarinic acetylcholine receptor agonist
- Unstable in solutions, freshly prepared is recommended
- Suitable for laboratory centrifugation and storage
Medchemexpress LLC Cyclobenzaprine hydrochloride | 6202-23-9 | 100 MG
Cyclobenzaprine (MK130) hydrochloride is an orally active 5-HT2 receptor antagonist that acts centrally to provide skeletal muscle relaxation, alleviate muscle spasms, and reduce pain. It also possesses antiparasitic activity. Cyclobenzaprine hydrochloride shows promise for research in acute, painful skeletal muscle disorders and infectious diseases.
- Acts centrally to provide skeletal muscle relaxation
- Alleviates muscle spasms and reduces pain
- Possesses antiparasitic activity
- Shows promise for research in acute, painful skeletal muscle disorders
- Shows promise for research in infectious diseases
Medchemexpress LLC Cyclen | 294-90-6 | 172.28 | 100 G
Cyclen is a macrocyclic tetraamine chelating agent and the aza analogue of crown ether. It is utilized as a precursor for MRI contrast agents and as an intermediate for preparing effective macrocyclic chelates. It functions as a structural regulator in the interfacial polymerization of polyethyleneimine (PEI) and trimesoyl chloride (TMC) to develop polyamide NF membranes for efficient Li+/Mg2+ separation. It possesses a specific cavity structure and exhibits selective coordination properties for Li+ ions.
- Macrocyclic tetraamine chelating agent
- Aza analogue of crown ether
- Utilized as a precursor for MRI contrast agents
- Intermediate for preparing effective macrocyclic chelates
- Functions as a structural regulator in interfacial polymerization
- Possesses a specific cavity structure
- Exhibits selective coordination properties for Li+ ions
Medchemexpress LLC Eloralintide (sodium) | 99.7% | 4526.10 | 1 MG
Eloralintide sodium is an Amylin Receptor agonist that selectively activates AMY1R and AMY3R in cells expressing human or rat AMY1R, AMY3R or CTR. It activates AMYRs and CTR in rats, leading to a sustained decrease in plasma Ca2+ levels. Eloralintide sodium reduces appetite and body weight in both lean and obese rats and can be used for research related to obesity.
- Selectively activates AMY1R and AMY3R
- Activates AMYRs and CTR in rats
- Leads to a sustained decrease in plasma Ca2+ levels
- Reduces appetite and body weight in lean and obese rats
- Useful for obesity research
Medchemexpress LLC Acetaminophen | 103-90-2 | 99.97% | C8H9NO2 | 10 G
Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor and a widely used antipyretic and analgesic agent. It is also a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor that induces ferroptosis and can lead to acute liver injury in mice models.
- Selective COX-2 inhibitor with an IC50 of 25.8 μM
- Widely used as an antipyretic and analgesic
- Potent hepatic N-acetyltransferase 2 (NAT2) inhibitor
- Induces ferroptosis
- Can lead to acute liver injury in mice models
(F)F.CC[N+](CC)=S(F)F | 5g | 444750970](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000482043.jpg-250.jpg)
eMolecules 63517-29-3 | (Diethylamino)difluorosulfonium Tetrafluoroborate | Accela ChemBio (ASD) | MFCD15144877 | 228.990 | C4H10BF6NS | 95.000 | F[B-](F)(F)F.CC[N+](CC)=S(F)F | 5g | 444750970
(Diethylamino)difluorosulfonium Tetrafluoroborate | Accela ChemBio (ASD) | 63517-29-3 | MFCD15144877 | 228.990 | C4H10BF6NS | 95.000 | F[B-](F)(F)F.CC[N+](CC)=S(F)F | 5g | 444750970
(F)F.CC[N+](CC)=S(F)F | 25g | 444750972](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000482045.jpg-250.jpg)
eMolecules 63517-29-3 | (Diethylamino)difluorosulfonium Tetrafluoroborate | Accela ChemBio (ASD) | MFCD15144877 | 228.990 | C4H10BF6NS | 95.000 | F[B-](F)(F)F.CC[N+](CC)=S(F)F | 25g | 444750972
(Diethylamino)difluorosulfonium Tetrafluoroborate | Accela ChemBio (ASD) | 63517-29-3 | MFCD15144877 | 228.990 | C4H10BF6NS | 95.000 | F[B-](F)(F)F.CC[N+](CC)=S(F)F | 25g | 444750972
Medchemexpress LLC Methyl 2-fluoro-4-((1-methoxy-2-methyl-1-oxopropan-2-yl)amino)benzoate | 1802242-47-2 | MFCD00006432 | 25g
Enzalutamide impurity 4 is an impurity of Enzalutamide (HY-70002)