Phenols
Medchemexpress LLC RS 67333 hydrochloride | 168986-60-5 | 99.7% | 389.36 g/mol | C19H30Cl2N2O2 | 5 MG
RS 67333 hydrochloride is a research-grade small-molecule partial agonist of the 5-HT4 (serotonin) receptor, supplied as a solid for laboratory use. It is intended for neuroscience and receptor-signaling studies and is provided with specification details and storage recommendations for research environments.
- Potent, selective 5-HT4 receptor partial agonist.
- High purity (≈99.7%).
- Molecular weight 389.36 g/mol.
- Solid, light yellow to yellow appearance.
- Recommended for research use only with sealed, moisture-free storage.
Medchemexpress LLC SBI-810 (hydrochloride) | 2772746-58-2 | 99.6% | 483.05 | 1 ML
SBI-810 hydrochloride is a functionally selected β-arrestin-biased neurotensin receptor 1 (NTSR1) allosteric modulator. It modulates NTSR1 G protein signaling in a G protein-specific manner in the presence of the endogenous ligand, neurotensin (NT). This compound fully antagonizes NT-induced activation of Gq, partially antagonizes NT-induced activation of Gi1, and is permissive of NTSR1 activation of GoA and G12.
- Functionally selected β-arrestin-biased neurotensin receptor 1 (NTSR1) allosteric modulator.
- Modulates NTSR1 G protein signaling in a G protein-specific manner with neurotensin (NT).
- Fully antagonizes NT-induced activation of Gq.
- Partially antagonizes NT-induced activation of Gi1.
- Permissive of NTSR1 activation of GoA and G12.
- For research use only.
eMolecules 1259484-97-3 | Medchem Express | SKI-178 | 5mg | 599150633 | HY-12892 | MFCD01913555 | 394.431 | C21H22N4O4
Ambeed | 7-Chloro-[124]triazolo[15-a]pyridine | 100mg | 601097454 | A515415 | 1427452-48-9 | MFCD23708543 | 153.570 | C6H4ClN3
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eMolecules Building Block Tool
![eMolecules 86347-15-1 | Medetomidine Hydrochloride | Key Organics/BIONET236.740 | C13H17ClN2 | 99.000 | Cl.CC(c1cnc[nH]1)c1cccc(C)c1C | 3mg | 564356413](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000128175.jpg-250.jpg)
eMolecules 86347-15-1 | Medetomidine Hydrochloride | Key Organics/BIONET236.740 | C13H17ClN2 | 99.000 | Cl.CC(c1cnc[nH]1)c1cccc(C)c1C | 3mg | 564356413
Medetomidine Hydrochloride | Key Organics/BIONET | 86347-15-1236.740 | C13H17ClN2 | 99.000 | Cl.CC(c1cnc[nH]1)c1cccc(C)c1C | 3mg | 564356413
=O | 1g | 537715216](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502148450.JPG-250.jpg)
eMolecules 99-57-0 | 2-Amino-4-nitrophenol | Oakwood Chemical | MFCD00007695 | 154.125 | C6H6N2O3 | 98.000 | Nc1cc(ccc1O)[N+]([O-])=O | 1g | 537715216
2-Amino-4-nitrophenol | Oakwood Chemical | 99-57-0 | MFCD00007695 | 154.125 | C6H6N2O3 | 98.000 | Nc1cc(ccc1O)[N+]([O-])=O | 1g | 537715216
Medchemexpress LLC GSK2945 (hydrochloride) | 2517771-89-8 | 98.5% | 457.80 | 1 ML
GSK2945 hydrochloride is a tertiary amine and a highly specific Rev-erbα/REV-ERBα (mouse/human reverse erythroblastosis virus α) antagonist with EC50s of 21.5 μM and 20.8 μM, respectively. It enhances cholesterol 7α-hydroxylase (CYP7A1) levels and cholesterol metabolism. For research use only.
- Highly specific Rev-erbα/REV-ERBα antagonist.
- Enhances cholesterol 7α-hydroxylase (CYP7A1) levels.
- Promotes cholesterol metabolism.
- Suitable for research applications.
Medchemexpress LLC AZD9056 hydrochloride | 345303-91-5 | 98.2% | 455.46 | 50 MG
AZD9056 hydrochloride is a selective orally active inhibitor of P2X7, which plays a significant role in inflammation and pain-causing diseases. It is for research use only and not sold to patients.
- Selective orally active inhibitor of P2X7.
- Blocks P2X7 receptors with an IC50 of 11.2 nM in HEK-hP2X7 cell line.
- Exhibits high selectivity for the P2X7 receptor.
- Has an inhibitory effect (IC50=1-3 μM) in mouse microglia BV2 cells.
- Weakly inhibits BCRP-mediated transport of methotrexate (IC50=92 μM).
- Exerts pain-relieving and anti-inflammatory effects in vivo.
- Reverses upregulated expression of IL-1β, IL-6, TNF-α, MMP-13, SP, and PGE2 induced by MIA in cartilage tissues.
Medchemexpress LLC Oxprenolol-d7 hydrochloride | 1189649-47-5 | 98.3% | 308.85 | C15H17D7ClNO3 | 10 MG
Oxprenolol-d7 hydrochloride is a deuterium-labeled hydrochloride salt of oxprenolol used as an analytical standard and internal standard for LC-MS and other quantitative assays. Supplied at high purity in mg-scale packages, follow recommended cold storage to preserve stability.
- Deuterium-labeled hydrochloride salt for use as an analytical/internal standard.
- High purity (98.25%) for accurate quantitation.
- Available in mg-scale packages to support method development.
- Recommended storage: powder -20°C (3 years) or 4°C (2 years).
- Molecular formula C15H17D7ClNO3 and molecular weight 308.85 for identification.
![Medchemexpress LLC Urea, N-[4-[4-(4-morpholinyl)-6-(3-oxa-8-azabicyclo[3.2.1]oct-8-yl)-1,3,5-triazin-2-yl]phenyl]-N'-4-pyridinyl-, hydrochloride (1:1) | 1463510-35-1 | 99.7% | 525.00 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-250.jpg)
Medchemexpress LLC Urea, N-[4-[4-(4-morpholinyl)-6-(3-oxa-8-azabicyclo[3.2.1]oct-8-yl)-1,3,5-triazin-2-yl]phenyl]-N'-4-pyridinyl-, hydrochloride (1:1) | 1463510-35-1 | 99.7% | 525.00 | 25 MG
PKI-179 hydrochloride is a potent and orally active dual PI3K/mTOR inhibitor. It shows anti-tumor activity in vivo, inhibiting tumor growth and PI3K signaling without significant weight loss in animal models. The product is suitable for laboratory research applications.
- Potent and orally active dual PI3K/mTOR inhibitor
- Anti-tumor activity in vivo
- Inhibits cell proliferation
- Available as a white to off-white solid
- Tested and complies with specifications
Medchemexpress LLC AT7519 Hydrochloride | 902135-91-5 | 98.6% | C16H18Cl3N5O2 | 25 MG
AT7519 Hydrochloride is a potent inhibitor of CDKs, with IC50s of 210, 47, 100, 13, 170, and <10 nM for CDK1, CDK2, CDK4 to CDK6, and CDK9, respectively. It is for research use only.
- Potent inhibitor of CDKs.
- Induces dose-dependent cytotoxicity and apoptosis in multiple myeloma cells.
- Inhibits cell cycle progression and induces apoptosis in human tumor cell lines.
- Inhibits transcription and RNA polymerase II in leukemia cell lines.
- Inhibits tumor growth in human xenograft mouse models.
- Investigated in clinical trials for various cancers.
Medchemexpress LLC BN82002 hydrochloride | 1049740-43-3 | 99.4% | 395.88 | 10 MG
BN82002 hydrochloride is a potent, selective, and irreversible inhibitor of the CDC25 phosphatase family. It demonstrates significant inhibitory activity against various CDC25 isoforms including CDC25A, CDC25B2, CDC25B3, CDC25C, and 25C-cat, with IC50 values ranging from 2.4 to 6.3 μM. This compound also exhibits high selectivity, showing approximately 20-fold greater inhibition over CD45 tyrosine phosphatase.
- Potent and selective CDC25 phosphatase inhibitor
- Inhibits CDC25A, CDC25B2, CDC25B3, CDC25C, and 25C-cat
- Demonstrates approximately 20-fold greater selectivity over CD45 tyrosine phosphatase
- Irreversible inhibitor