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Aromatic organic compounds that consist of a phenyl functional group (−C6H5) bonded to a hydroxyl functional group (−OH). Includes compounds with more substitutions and derivatives.
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2-Chloro-3-pyridinol is a biochemical reagent suitable for use as a biological material or organic compound in life science research. It can also be utilized in the synthesis of other active compounds. Additionally, it is identified as a halopyridinol disinfection byproduct found in drinking water samples. For research use only, not for sale to patients.
Biochemical reagent
Used as a biological material
Used as an organic compound in life science research
Utilized in the synthesis of other active compounds
Identified as a halopyridinol disinfection byproduct
For research use only
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2-Chloro-3-pyridinol is a biochemical reagent useful as a biological material or organic compound for life science-related research. It can also be used in the synthesis of other active compounds. This compound is also identified as a halopyridinol disinfection by-product in drinking water samples. In vitro studies show that 2-Chloro-3-pyridinol exhibits very low cytotoxicity to human hepatocellular carcinoma HepG2 cells, with an EC50 > 10000 μM.
Can be used as a biological material or organic compound for research
Useful in the synthesis of other active compounds
Exhibits very low cytotoxicity to human hepatocellular carcinoma HepG2 cells
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2-Chloro-3-pyridinol is a biochemical reagent suitable for life science-related research as a biological material or organic compound. It also serves as an intermediate in the synthesis of other active compounds.
Biochemical reagent for life science research
Used in the synthesis of other active compounds
Identified as a halopyridinol disinfection by-product in drinking water samples
Demonstrates very low cytotoxicity to human hepatocellular carcinoma HepG2 cells in vitro
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
2-Chloro-3-pyridinol is a biochemical reagent useful in life science research and for synthesizing active compounds. It is also found as a halopyridinol disinfection by-product in drinking water samples.
Can be used as a biological material or organic compound
Suitable for life science related research
Can be used in the synthesis of other active compounds
Low cytotoxicity to human hepatocellular carcinoma HepG2 cells
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
2-Chloro-3-pyridinol is a biochemical reagent used as a biological material or organic compound for life science research. It can also be utilized in the synthesis of other active compounds. Additionally, it is identified as a halopyridinol disinfection by-product found in drinking water samples. In vitro studies show that 2-Chloro-3-pyridinol exhibits very low cytotoxicity to human hepatocellular carcinoma HepG2 cells, with an EC50 > 10000 μM.
Biochemical reagent for life science research.
Used in the synthesis of other active compounds.
Identified as a halopyridinol disinfection by-product.
Exhibits very low cytotoxicity to HepG2 cells.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
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ML-00253764 hydrochloride is a brain-penetrant, nonpeptidic melanocortin receptor 4 (MC4R) antagonist. This compound exhibits a Kᵢ of 0.16 μM and an IC₅₀ of 0.103 μM, and is capable of crossing the blood-brain barrier. It is intended for research use only.
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ML-00253764 hydrochloride is a brain penetrant nonpeptidic melanocortin receptor 4 (MC4R) antagonist. It can cross the blood-brain barrier and is suitable for research applications.
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
ML-00253764 hydrochloride is a brain penetrant, nonpeptidic melanocortin receptor 4 (MC4R) antagonist with Ki and IC50 values of 0.16 μM and 0.103 μM, respectively. It is capable of crossing the blood-brain barrier.
Brain penetrant: can cross the blood-brain barrier.
In vitro activity: displaces NDP-α-MSH binding with a mean IC50 of 0.32 μM for hMC4-R, 0.81 μM for hMC3-R, and 2.12 μM for hMC5-R. At 100 μM, it decreases cAMP production induced by [NLE4,D-Phe7]-α-melanocyte stimulating hormone ([NDP]-α-MSH) by 20% in MC4R-expressing HEK293 cell membranes, but shows no effect on cAMP levels in MC3R- or MC5R-expressing membranes.
In vivo activity: in CT-26 tumor-bearing BALB/c mice, subcutaneous injection (3, 10, or 30 mg/kg; once daily) showed protection against tumor-induced body weight loss.
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
ML-00253764 hydrochloride is a brain penetrant nonpeptidic melanocortin receptor 4 (MC4R) antagonist with a Ki and IC50 of 0.16 μM and 0.103 μM, respectively. It can cross the blood-brain barrier.
Acts as a melanocortin receptor 4 (MC4R) antagonist.
Crosses the blood-brain barrier.
Decreases cAMP production in MC4R-expressing HEK293 cell membranes.
Demonstrates in vivo protection against tumor-induced body weight loss in mouse models.
Off-white to light yellow solid appearance.
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Delta-nonalactone (δ-nonalactone) is a cyclic lactone (C9H16O2, CAS 3301-94-8) used as a flavor and fragrance ingredient and in laboratory research. It is a colorless to pale yellow liquid with a coconut-like odor and is supplied at high purity for analytical and experimental use.
High purity appropriate for research and analytical use.
Coconut-like aroma for flavor and fragrance formulation.
Reported insect-repellent activity against tsetse flies.
Colorless to pale yellow liquid at ambient conditions.
Density approximately 0.994-0.999 g/mL.
Used in biochemical assays and metabolic research.
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
ML-00253764 hydrochloride is a brain penetrant nonpeptidic melanocortin receptor 4 (MC4R) antagonist with a Ki and IC50 of 0.16 μM and 0.103 μM, respectively. It can cross the blood-brain barrier.
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
ML-00253764 hydrochloride is the hydrochloride salt of a brain-penetrant, nonpeptidic antagonist of the melanocortin 4 receptor (MC4R) used in pharmacological research. It exhibits submicromolar binding and functional inhibition of MC4R, is supplied as a high-purity solid, and is intended for in vitro and in vivo studies when handled and stored according to manufacturer recommendations.