Phenols
Medchemexpress LLC Sodium diatrizoate | 737-31-5 | 99.6% | 1 ML
Sodium diatrizoate is an iodinated radiocontrast agent. It has potential for radiographic imaging of the airways and induces mitochondrial turnover and oxidative stress, activating apoptosis by dysregulating calcium.
- Iodinated radiocontrast agent
- Potential for radiographic imaging of the airways
- Induces mitochondrial turnover and oxidative stress
- Activates apoptosis by dysregulating calcium
Medchemexpress LLC Dronedarone Hydrochloride | 141625-93-6 | 99.99% | C31H45ClN2O5S | 25 MG
Dronedarone Hydrochloride is a non-iodinated amiodarone derivative that inhibits Na+, K+, and Ca2+ currents. It is intended for research use only and not sold to patients.
- Inhibits Na+, K+, and Ca2+ currents
- Non-iodinated amiodarone derivative
- Potent inhibitor of acetylcholine-activated K+ current
- Blocks IKr and ICa-L
- Reduces incidence of ventricular fibrillation
- Inhibits carotid artery thrombus formation in vivo
Medchemexpress LLC 5-Bromo-2-iodopyridine | 223463-13-6 | 283.89 | 50 G
5-Bromo-2-iodopyridine is a pyridine derivative containing bromine and iodine. It can be used in the synthesis of other active compounds, such as Lonafarnib. It can also react with active zinc under mild conditions to form 5-bromo-2-pyridylzinc iodide, which is utilized in various coupling reactions to obtain corresponding cross-coupling products.
- Pyridine derivative containing bromine and iodine
- Used in the synthesis of active compounds like Lonafarnib
- Reacts with active zinc to form 5-bromo-2-pyridylzinc iodide
- Utilized in various coupling reactions
Medchemexpress LLC Dronedarone Hydrochloride | 141625-93-6 | 99.99% | C31H45ClN2O5S | 100 MG
Dronedarone Hydrochloride is a non-iodinated amiodarone derivative that inhibits Na+, K+, and Ca2+ currents. It serves as a multichannel blocker for atrial fibrillation, making it suitable for various research applications.
- Inhibits Na+, K+, and Ca2+ currents.
- Potently blocks acetylcholine-activated K+ current.
- Blocks IKr and ICa-L with specific IC50 values.
- Exhibits state-dependent inhibition of fast Na+ channel current.
- Significantly reduces incidence of ventricular fibrillation in vivo.
- Inhibits carotid artery thrombus formation in vivo.
Medchemexpress LLC Dronedarone (hydrochloride) | 141625-93-6 | 99.99% | C31H45ClN2O5S | 500 MG
Dronedarone Hydrochloride is a non-iodinated amiodarone derivative that inhibits Na+, K+, and Ca2+ currents. It serves as a multichannel blocker for atrial fibrillation, demonstrating various inhibitory effects on ion channels and biological activities.
- Inhibits Na+, K+, and Ca2+ currents
- Potent inhibitor of acetylcholine-activated K+ current
- Blocks IKr (IC50=3 μM) and ICa-L (IC50=0.18 μM)
- Reduces the incidence of ventricular fibrillation in rats
- Inhibits carotid artery thrombus formation
- Impairs thrombin- and collagen-induced platelet aggregation
Medchemexpress LLC Dronedarone Hydrochloride | 141625-93-6 | MFCD00914940 | 99.99% | C31H45ClN2O5S | 5 MG
Dronedarone Hydrochloride is a non-iodinated amiodarone derivative that inhibits Na+, K+, and Ca2+ currents. This compound is intended for research use only, acting as a multichannel blocker for atrial fibrillation by modulating various ion channels.
- Inhibits Na+, K+, and Ca2+ currents
- Molecular weight of 593.22
- Appears as a white to off-white solid
- Ships at room temperature in continental US
- Storage recommendations for solid: 4°C, sealed, away from moisture
- Storage recommendations for solvent: -80°C for 6 months; -20°C for 1 month, sealed, away from moisture
Medchemexpress LLC 2,4,6-triiodophenol | 609-23-4 | MFCD00002179 | 99.5% | 471.80 g/mol | C6H3I3O | 100 MG
2,4,6-triiodophenol is an iodinated phenol supplied for laboratory research and described as an orally active inhibitor of leukotriene B4 (LTB4) synthesis. It is provided as a solid and has documented biological activity including induction of apoptosis in mouse blastocysts.
- cas number: 609-23-4.
- chemical formula: C6H3I3O.
- molecular weight: 471.80 g/mol.
- reported purity: catalog lists 98.0%; batch COA reports 99.52%.
- biological activity: LTB4 synthesis inhibitor.
- observed effect: can induce apoptosis in mouse blastocysts.
- form and packaging: solid powder, supplied in multiple sizes including 100 mg.
Medchemexpress LLC Dronedarone Hydrochloride | 141625-93-6 | 99.99% | C31H45ClN2O5S | 50 MG
Dronedarone Hydrochloride is a non-iodinated amiodarone derivative acting as a multichannel blocker for atrial fibrillation. It inhibits Na+, K+, and Ca2+ currents and is a potent inhibitor of acetylcholine-activated K+ current, rapid delayed rectifier, and L-type calcium current.
- Inhibits human Kv1.5 channel with an IC50 of 2.37 μM.
- Blocks IKr (IC50=3 μM) and ICa-L (IC50=0.18 μM).
- Exhibits state-dependent inhibition of fast Na+ channel current.
- Reduces incidence of ventricular fibrillation (VF) in rats.
- Inhibits carotid artery thrombus formation in vivo.
- Impairs thrombin- and collagen-induced platelet aggregation.
- Reduces expression of plasminogen activator inhibitor-1 (PAI1).
Medchemexpress LLC Dronedarone Hydrochloride | 141625-93-6 | 99.99% | C31H45ClN2O5S | 200 MG
Dronedarone Hydrochloride is a non-iodinated amiodarone derivative that acts as a multichannel blocker for atrial fibrillation by inhibiting Na+, K+, and Ca2+ currents.
- Inhibits Na+, K+, and Ca2+ currents
- Acts as a multichannel blocker for atrial fibrillation
- Potently inhibits acetylcholine-activated K+ current
- Blocks IKr (IC50=3 μM) and ICa-L (IC50=0.18 μM) under whole-cell patch clamp
- Exhibits state-dependent inhibition of fast Na+ channel current
- Reduces incidence of ventricular fibrillation in rats
- Inhibits carotid artery thrombus formation in vivo
- Impairs thrombin- and collagen-induced platelet aggregation
- Reduces expression of plasminogen activator inhibitor-1 (PAI1)
Medchemexpress LLC Dronedarone Hydrochloride | 141625-93-6 | MFCD00947708 | 99.99% | C31H45ClN2O5S | 1 ML
Dronedarone Hydrochloride is a non-iodinated amiodarone derivative that inhibits Na+, K+ and Ca2+ currents. It acts as a multichannel blocker for atrial fibrillation, potently inhibiting acetylcholine-activated K+ currents and rapid delayed rectifier K+ currents.
- Inhibits Na+, K+, and Ca2+ currents
- Acts as a multichannel blocker for atrial fibrillation
- Potently inhibits acetylcholine-activated K+ current
- Inhibits rapid delayed rectifier and L-type calcium currents
- Blocks IKr and ICa-L
- Exhibits state-dependent inhibition of fast Na+ channel current
- Significantly reduces incidence of ventricular fibrillation
- Inhibits carotid artery thrombus formation in vivo
- Impairs thrombin- and collagen-induced platelet aggregation
- Reduces expression of plasminogen activator inhibitor-1 (PAI1)