Carboxylic acids and derivatives
Medchemexpress LLC Vtp50469 (fumarate) | 2169919-29-1 | 99.8% | 804.93 | 50 MG
Vtp50469 (fumarate) | 2169919-29-1 | 99.8% | 804.93 | 50 MG
TARGETMOL CHEMICALS INC AVITINIB MALEATE 10MG
Also available in 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Avitinib maleate is a pyrrolopyrimidine-based irreversible epidermal growth factor receptor (EGFR) inhibitor. purity: 99%
Medchemexpress LLC Indacaterol maleate (standard) | 753498-25-8 | 99.6% | C28H32N2O7 | 100 MG
Indacaterol maleate (standard) | 753498-25-8 | 99.6% | C28H32N2O7 | 100 MG
eMolecules 37526-88-8 | Benzyl tiglate stabilized with 0.1% alpha-tocopherol | Oakwood Chemical | MFCD00017279 | 190.242 | C12H14O2 | 0.000 | C\C=C(/C)C(=O)OCc1ccccc1 | 1g | 537710580
Benzyl tiglate stabilized with 0.1% alpha-tocopherol | Oakwood Chemical | 37526-88-8 | MFCD00017279 | 190.242 | C12H14O2 | 0.000 | C\C=C(/C)C(=O)OCc1ccccc1 | 1g | 537710580
Medchemexpress LLC Neratinib (maleate) | 915942-22-2 | 99.7% | 673.11 | 5 MG
Neratinib maleate is an orally available, irreversible, and highly selective inhibitor of HER2 and EGFR. It effectively inhibits the proliferation of cell lines expressing high levels of HER-2 and shows anticancer activities in tumor xenograft models. This compound induces G1-S phase arrest and leads to inhibition of MAPK and Akt phosphorylation.
- Orally available
- Irreversible, highly selective HER2 and EGFR inhibitor
- Inhibits proliferation of HER-2 expressing cell lines
- Induces G1-S phase arrest
- Inhibits MAPK and Akt phosphorylation
- Shows anticancer activity in tumor xenograft models
Medchemexpress LLC Tegaserod maleate | 189188-57-6 | 99.9% | C20H27N5O5 | 500 MG
Tegaserod maleate is an orally active serotonin receptor 4 (HTR4; 5-HT4R) agonist and a 5-HT2B receptor antagonist, with pKis of 7.5, 8.4, and 7.0 for human recombinant 5-HT2A, 5-HT2B, and 5-HT2C receptors. This compound induces tumor cell apoptosis, blunts PI3K/Akt/mTOR signaling, and decreases S6 phosphorylation. It exhibits anti-tumor activity and shows potential for irritable bowel syndrome (IBS) research.
- Orally active serotonin receptor 4 (HTR4; 5-HT4R) agonist
- 5-HT2B receptor antagonist
- Induces tumor cell apoptosis
- Blunts PI3K/Akt/mTOR signaling
- Decreases S6 phosphorylation
- Exhibits anti-tumor activity
- Potential for irritable bowel syndrome (IBS) research
Medchemexpress LLC Cipralisant maleate | 223420-20-0 | 99.8% | 332.4 g/mol | C18H24N2O4 | 5 MG
Cipralisant maleate is the maleate salt of cipralisant, a potent and selective histamine H3 receptor ligand that functions as a full antagonist in vivo and an agonist in vitro. Supplied for research use in neuroscience and pharmacology, the compound offers high purity, good DMSO solubility, and defined storage conditions for stability.
- Potent, selective histamine H3 receptor antagonist in vivo.
- Agonist activity observed in vitro.
- High reported purity (99.84%).
- Soluble in DMSO at ≥ 100 mg/mL.
- Molecular weight 332.4 g/mol.
- Recommended storage: powder -20°C for long term, 4°C for short term.
Apexbio Technology LLC CGP 3466B maleate 200189-97-5 50mg
CGP 3466B maleate (CAS 200189-97-5) is a structural derivative of R-( )-Deprenyl but has negligible monoamine oxidase-B inhibitory activity It acts as a neuroprotective agent through inhibition of apoptotic cell death pathways In vitro studies demonstrate that CGP 3466B prevents apoptosis in human neuroblastoma cells PC-12 cells and cerebellar granule cells exposed to cytosine arabinoside In vivo data from the pmn/pmn mouse model of motor neuron disease showed that oral administration of CGP 3466B delayed disease progression maintained motor function and significantly extended survival CGP 3466B is thus under investigation as a potential therapeutic for neurodegenerative conditions
eMolecules ChemScene / (Chloromethyl)triethoxysilane / 5g / 536799853 / CS-0086574 / 0.000 / 15267-95-5 / MFCD00039354 / 212.750 / C7H17ClO3Si
ChemScene / (Chloromethyl)triethoxysilane / 5g / 536799853 / CS-0086574 / 0.000 / 15267-95-5 / MFCD00039354 / 212.750 / C7H17ClO3Si
Medchemexpress LLC Perhexiline maleate | 6724-53-4 | 99.97% | 200 MG
Perhexiline maleate is an orally active inhibitor of CPT1 and CPT2, which functions to reduce fatty acid metabolism. This compound is known to induce mitochondrial dysfunction and apoptosis in hepatic cells. It can cross the blood-brain barrier and has demonstrated anti-tumor activity, making it relevant for research in cancers and cardiovascular diseases such as angina.
- Reduces fatty acid metabolism.
- Induces mitochondrial dysfunction in hepatic cells.
- Induces apoptosis in hepatic cells.
- Crosses the blood-brain barrier.
- Shows anti-tumor activity.
- Used in research for cancers and cardiovascular disease like angina.
(C)C(C)(C)C)NC(=O)OC(C)(C)C | 500mg | 794076077](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502477968.JPG-250.jpg)
eMolecules 112418-19-6 | Methyl N-(tert-butoxycarbonyl)-O-(tert-butyldimethylsilyl)-D-serinate | Synthonix | MFCD28403203 | 333.500 | C15H31NO5Si | 98.000 | COC(=O)[C@@H](CO[Si](C)(C)C(C)(C)C)NC(=O)OC(C)(C)C | 500mg | 794076077
Methyl N-(tert-butoxycarbonyl)-O-(tert-butyldimethylsilyl)-D-serinate | Synthonix | 112418-19-6 | MFCD28403203 | 333.500 | C15H31NO5Si | 98.000 | COC(=O)[C@@H](CO[Si](C)(C)C(C)(C)C)NC(=O)OC(C)(C)C | 500mg | 794076077
Medchemexpress LLC Enalapril maleate (Standard) | 76095-16-4 | 99.95% | 50 MG
Enalapril maleate (Standard) is an analytical standard and an angiotensin-converting enzyme (ACE) inhibitor. This product is intended for research and analytical applications, commonly used in qualitative, quantitative, and methodological experiments such as HPLC, GC, and MS.
- Analytical standard for research and analytical applications
- Angiotensin-converting enzyme (ACE) inhibitor
- Suitable for HPLC, GC, and MS research experiments
- Molecular weight: 492.52
- Formula: C₂₄H₃₂N₂O₉
- Appearance: solid
- Color: white to off-white
Sigma Aldrich Fine Chemicals Biosciences 2-Hydroxyethyl methacrylate embedding medium (for microscopy) | 868-77-9 | MFCD00002863 | 250ML
2-Hydroxyethyl methacrylate embedding medium (for microscopy) | Purity: >=99% | Mol Wt: 130.14 | 868-77-9 | MFCD00002863 | 250ML
Selleck Chemical LLC Pyrilamine Maleate S4382-25mg
Pyrilamine Maleate (Mepyramine)is a histamine H1 receptor inverse agonist it binds to a G protein-coupled form of the receptor and promotes a G protein-coupled inactive state of the H1 receptor that interferes with the Gq/11-mediated signaling
Medchemexpress LLC PD-168077 maleate | 630117-19-0 | 99.6% | 450.49 | 50 MG
PD-168077 maleate is a selective dopamine D4 receptor agonist with a Ki of 9 nM. It exhibits high selectivity over other D2-like and D1-like receptor family members, as well as α1, α2, 5-HT1A, and 5-HT2A receptors. This compound shows intrinsic activity at the D4 receptor, inhibiting forskolin-stimulated cAMP accumulation or stimulating [3H]thymidine uptake in CHO cells expressing the human D4 receptor. In vivo, PD-168077 dose-dependently induces locomotion.
- Selective dopamine D4 receptor agonist
- Exhibits high selectivity over other D2-like, D1-like, α1, α2, 5-HT1A, and 5-HT2A receptors
- Shows intrinsic activity at the D4 receptor
- Induces locomotion in vivo