Aminobenzoic acids and derivatives
Selleck Chemical LLC Obatoclax Mesylate (GX15-070) S1057-10mM/1mL
Obatoclax Mesylate (GX15-070) is an antagonist of Bcl-2 with Ki of 0 22 M in a cell-free assay can assist in overcoming MCL-1 mediated resistance to apoptosis
Medchemexpress LLC 9-ethyl-9H-carbazol-3-amine | 132-32-1 | MFCD00004964 | 99.6% | 210.28 g/mol | C14H14N2 | 100 G
3-Amino-9-ethylcarbazole (9-ethyl-9H-carbazol-3-amine) is an organic small molecule used as a chromogenic peroxidase substrate in immunohistochemistry and as a building block in organic electronic materials and synthetic chemistry. It is typically supplied as a solid powder with molecular formula C14H14N2 and molecular weight 210.28 g/mol.
- Chromogenic peroxidase substrate for histochemical and blotting assays.
- Versatile building block for organic electronics and small-molecule synthesis.
- High purity suitable for analytical and synthetic use.
- Available in multiple pack sizes to support research-scale needs.
- Certificate of analysis available to document batch quality.
Medchemexpress LLC Succinyl-Coenzyme A sodium | 108347-97-3 | ≥99.0% | 1 MG
Succinyl-Coenzyme A sodium is a pivotal intermediate metabolite in the tricarboxylic acid cycle and a key coenzyme A metabolite. It is biosynthesized from α-ketoglutarate or propionyl-CoA. Succinyl-Coenzyme A sodium acts as a critical precursor and substrate for heme biosynthesis and gluconeogenesis. Insufficiency of Succinyl-Coenzyme A sodium caused by cobalamin deficiency is directly linked to growth retardation, impaired heme synthesis, tissue glycine accumulation, and neurological abnormalities.
- It can be used in research on metabolic, neurological, and hematological abnormalities (such as porphyria) caused by nutritional vitamin B12 deficiency (leading to a lack of Succinyl-Coenzyme A synthesis).
- It acts as a substrate for rat liver δ-aminolevulinic acid synthase-1 with a Michaelis constant (Km) of 6-120 μmol/L.
- It does not bind to recombinant NLRX1 in an in vitro pull-down assay.
Medchemexpress LLC Pergolide (mesylate) | 66104-23-2 | 410.59 | 50 MG
Pergolide mesylate, an Ergoline derivative, is a potent and orally active dopamine D1 and D2 receptors agonist. It can be used for Parkinson's disease and hyperprolactinaemia research.
- Potent and orally active dopamine D1 and D2 receptors agonist.
- Inhibits H2O2-induced cell death in SH-SY5Y neuroblastoma cells.
- Protects SH-SY5Y neuroblastoma cells from cell death at low concentrations.
- Reduces working/reference memory errors in a rat model of Parkinson's disease.
- Facilitates spatial memory and improves brain oxidative balance in animal models.
Apexbio Technology LLC Concanamycin A(Synonyms: Folimycin, Concanamycin-A, ConcanamycinA, Concanamycin A (Folimycin), Folimycins), 1mg, CAS: 80890-47-7.
Concanamycin A (CAS 80890-47-7) is a selective inhibitor of vacuolar-type ATPase (V-ATPase) displaying an IC50 of approximately 10 nM Its mechanism involves direct binding to the V(o) subunit c of V-ATPase thereby inhibiting proton transport across cell membranes Through blockade of V-ATPase activity concanamycin A inhibits endosomal acidification disrupts intracellular trafficking processes and interferes with extracellular matrix pH maintenance resulting in apoptosis induction in tumor cells including oral squamous cell carcinoma and prostate cancer lines and reduced tumor cell invasiveness It is employed extensively in cancer biology research to investigate V-ATPase-mediated pathways and explore therapeutic resistance mechanisms
TARGETMOL CHEMICALS INC ANACARDIC ACID 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Anacardic Acid (6-pentadecylsalicylic Acid) is an effective inhibitor of p300 and p300/CBP-associated factor histone acetyltranferases. It also has antimicrobial activity antibacterial activity and inhibits prostaglandin synthase lipoxygenase and tyrosinase. purity: 99%
TARGETMOL CHEMICALS INC CAY10594 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. CAY10594 is a potent phospholipase D2(PLD2) inhibitor. CAY10594 ameliorates acetaminophen-induced acute liver injury by regulating the phosphorylated-GSK-3(beta)/JNK axis. purity: 98%
TARGETMOL CHEMICALS INC MUPIROCIN 50MG
Also available in 5 mg 10 mg 25 mg 100 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Mupirocin (BRL-4910A) is a RNA synthetase inhibitor antibacterial. It has shown excellent activity against gram-positive staphylococci and streptococci. purity: 98%
Medchemexpress LLC Chelidamic acid | 138-60-3 | MFCD00066478 | 99.9% | 183.12 g/mol | C7H5NO5 | 100 G
Chelidamic acid is a small-molecule research reagent (CAS 138-60-3) used as an amino acid decarboxylase inhibitor in biochemical and pharmacological research. It is supplied as a high-purity solid and as a 10 mM solution in DMSO for use in assays and compound libraries.
- High purity suitable for research applications.
- Available as a solid in multiple pack sizes, including large-scale options.
- Also provided as a ready-to-use 10 mM solution in DMSO.
- Molecular formula C7H5NO5 and molecular weight 183.12 g/mol.
- Appropriate for biochemical assays and inhibitor screening.
Selleck Chemical LLC A-438079 HCl
A-438079 HCl is a potent and selective P2X7 receptor antagonist with pIC50 of 6 9
AdipoGen Decoyinine Angustmycin A
Chemical. CAS 2004-04-8. Formula C11H13N5O4. MW 279.3. Isolated from Streptomyces sp. S 2113. Nucleoside antibiotic. Antitumor compound. Xanthosine monophosphate XMP aminase inhibitor. RNA synthesis inhibitor. Specific GMP synthase inhibitor. Reduces intracellular GTP levels.
Aobchem 3-Amino-5-chlorobenzoic acid | ≥95% | CAS 21961-30-8 | C7H6ClNO2 | 10g
3-Amino-5-chlorobenzoic acid | ≥95% | CAS 21961-30-8 | C7H6ClNO2 | 10g
Aobchem 4-Bromo-3-methylbenzamide | ≥97% | CAS 170229-98-8 | C8H8BrNO | 10g
4-Bromo-3-methylbenzamide | ≥97% | CAS 170229-98-8 | C8H8BrNO | 10g
Aobchem 4-Bromo-2-fluoro-5-methylbenzonitrile | ≥95% | CAS 916792-13-7 | C8H5BrFN | 10g
4-Bromo-2-fluoro-5-methylbenzonitrile | ≥95% | CAS 916792-13-7 | C8H5BrFN | 10g
TARGETMOL CHEMICALS INC PENTHIOPYRAD 5MG
Also available in 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Penthiopyrad (MTF-753) shows a broad spectrum of antifungal activity and suppresses fungal respiration. Penthiopyrad can be used in studies about foliar and soil-borne plant diseases. purity: 100%