Benzenesulfonamides
Electron Microscopy Sciences SEM Scintillator YAP 6.2x1 mm
YAP (Yttrium Aluminum Perovskite activated by Ce3+) shares the same advantages as YAG but is more efficient in terms of light output than YAG crystals. As well, the emission spectrum peaks at about 378nm, and this corresponds closely to the maximum sensitivity of the S11 photocathode which in general is used in most scanning electron microscopes. (There would be more improvement in signal by using a YAP crystal rather than YAG in these microscopes). The decay time of YAP (40ns) is faster than YAG (80ns) so its overall performance is superior to YAG.
YAP crystals should be coated with 50nm of aluminum prior to use. Note: P-47 is usually in-stock. YAG and YAP delivery time is 6-8 weeks. Use with Phillip Quad Detector.
AA BLOCKS LLC n-fluorobenzenesulfonamide | 145490-75-1 | 175.18 g/mol | 10G
n-fluorobenzenesulfonamide | 145490-75-1 | 175.18 g/mol | 10G
Medchemexpress LLC Seclidemstat mesylate | 2044953-70-8 | 99.8% | 547.04 g·mol⁻¹ | C21H27ClN4O7S2 | 25 MG
Seclidemstat mesylate is a reversible, noncompetitive small-molecule inhibitor of lysine-specific demethylase 1 (LSD1/KDM1A) supplied as the mesylate salt for preclinical research. It is provided as a high-purity solid and formulated options for biochemical and cell-based studies in oncology and antiviral research.
- Reversible, noncompetitive LSD1 inhibitor (reported Ki = 31 nM, IC50 = 13 nM).
- High purity (99.8%) suitable for biochemical and cell-based assays.
- Available in multiple quantities, including 25 MG and 10 mM solution in DMSO.
- Mesylate salt form for improved handling and stability.
- Applicable to research in Ewing sarcoma, SWI/SNF-mutated cancers, and antiviral studies.
Medchemexpress LLC GSTO1-IN-1 | 568544-03-6 | 99.1% | 311.18 | 1 MG
GSTO1-IN-1 is a potent inhibitor of glutathione S-transferase omega 1 (GSTO1) with an IC50 of 31 nM. It is intended for research use only. In cellular studies, it inhibits GSTO1 enzyme activity, decreases HCT116 cell viability dose-dependently, and inhibits clonogenic survival at sub-micromolar concentrations. In in vivo studies, it significantly inhibited tumor growth in a human colon cancer cell line xenograft model in nude mice without overt signs of toxicity or significant variations in average body weights over a 5-week treatment period.
- Potent GSTO1 inhibitor with an IC50 of 31 nM.
- Inhibits GSTO1 enzyme activity.
- Decreases HCT116 cell viability.
- Inhibits clonogenic survival.
- Significantly inhibits tumor growth in xenograft models.
- Well tolerated in in vivo studies.
eMolecules 17497-85-7 | 1,3,5-Tribromo-1,3,5-triazinane-2,4,6-trione | Accela ChemBio (ASD) | MFCD21604032 | 365.763 | C3Br3N3O3 | 95.000 | Brn1c(=O)n(Br)c(=O)n(Br)c1=O | 25g | 507751983
1,3,5-Tribromo-1,3,5-triazinane-2,4,6-trione | Accela ChemBio (ASD) | 17497-85-7 | MFCD21604032 | 365.763 | C3Br3N3O3 | 95.000 | Brn1c(=O)n(Br)c(=O)n(Br)c1=O | 25g | 507751983
Medchemexpress LLC Su11274 (PKI-SU11274) | 658084-23-2 | 98.8% | 5 MG
SU11274 is a small-molecule selective inhibitor of the c-Met (HGFR) receptor tyrosine kinase with a reported IC50 of 10 nM. It is supplied as a high-purity research reagent suitable for biochemical and cellular studies of Met-driven signaling pathways.
- Selective c-Met inhibitor with reported IC50 of 10 nM.
- High purity, approximately 98.8% (HPLC).
- Molecular formula C28H30ClN5O4S.
- Molecular weight 568.1 g/mol.
- Available in multiple pack sizes, including 5 mg.
- Safety data sheet available for handling and storage information.
![eMolecules 127-56-0 | Sulfacetamide sodium | Combi-Blocks, Inc. | MFCD00007885 | 236.220 | C8H9N2NaO3S | 98.000 | [Na+].CC(=O)[N-]S(=O)(=O)c1ccc(N)cc1 | 25g | 603132938](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502185650.JPG-250.jpg)
eMolecules 127-56-0 | Sulfacetamide sodium | Combi-Blocks, Inc. | MFCD00007885 | 236.220 | C8H9N2NaO3S | 98.000 | [Na+].CC(=O)[N-]S(=O)(=O)c1ccc(N)cc1 | 25g | 603132938
Sulfacetamide sodium | Combi-Blocks, Inc. | 127-56-0 | MFCD00007885 | 236.220 | C8H9N2NaO3S | 98.000 | [Na+].CC(=O)[N-]S(=O)(=O)c1ccc(N)cc1 | 25g | 603132938
Medchemexpress LLC TMI-1 (WAY-171318) | 287403-39-8 | 99.6% | 398.50 | C17H22N2O5S2 | 25 MG
TMI-1 (WAY-171318) is a small-molecule research inhibitor of TNF-α converting enzyme (TACE/ADAM17) and several matrix metalloproteinases. It shows potent enzymatic activity (reported IC50 ≈ 8.4 nM for TACE), exhibits anti-proliferative and pro-apoptotic effects in cellular models, and modulates inflammatory cytokines such as TNF-α, IL-1β, and IL-6. Identifiers: CAS 287403-39-8; formula C17H22N2O5S2; MW 398.50.
- High purity (≈99.6%) suitable for research applications.
- Potent TACE inhibition with reported IC50 ≈ 8.4 nM.
- Induces apoptosis and inhibits cancer cell proliferation in cell models.
- Reduces inflammatory cytokine levels in neuronal and inflammatory models.
- Powder form stable under recommended low-temperature storage.
Medchemexpress LLC HY-122641B 5mg Medchemexpress, Deltasonamide 2 (TFA) CAS:2235358-74-2 Purity:>98%
Medchemexpress, HY-122641B 5mg Deltasonamide 2 (TFA) CAS:2235358-74-2 Deltasonamide 2 TFA is competitive, high affinity PDEδ inhibitor with a K d of ~385 pM [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Sildenafil | 139755-83-2 | C22H30N6O4S | 200 MG
Sildenafil (UK-92480) is a potent phosphodiesterase type 5 (PDE5) inhibitor with an IC50 of 5.22 nM. It demonstrates various cellular and in vivo activities, making it suitable for a range of research applications. This product is for research use only.
- Potent PDE5 inhibitor with an IC50 of 5.22 nM
- Inhibits human recombinant PDE5A1
- Potentiates ERK1/ERK2 phosphorylation
- Increases cell proliferation in S phase
- Significantly increases intracavernosal pressure (ICP) in dog models
- Reduces number of TL+-cells and microglia/macrophages in vivo
- Decreases flap necrosis in animal models by enhancing growth factor secretion
Cayman Chemical trns-carboxy GlImepIrIde 1mg
A metabolite of glimepiride; formed from glimepiride in a two-step process mediated by CYP2C9 and cytosolic enzymes
Electron Microscopy Sciences SEM Scintillator YAP 19.0x7.3 mm
YAP (Yttrium Aluminum Perovskite activated by Ce3+) shares the same advantages as YAG but is more efficient in terms of light output than YAG crystals. As well, the emission spectrum peaks at about 378nm, and this corresponds closely to the maximum sensitivity of the S11 photocathode which in general is used in most scanning electron microscopes. (There would be more improvement in signal by using a YAP crystal rather than YAG in these microscopes). The decay time of YAP (40ns) is faster than YAG (80ns) so its overall performance is superior to YAG.
YAP crystals should be coated with 50nm of aluminum prior to use. Note: P-47 is usually in-stock. YAG and YAP delivery time is 6-8 weeks. Use with ARL SEMQ scanning electron microscopes.
Medchemexpress LLC dTRIM24 | 2170695-14-2 | 99.89% | 1113.30 | 10 MG
dTRIM24 is a selective bifunctional degrader of TRIM24, designed to suppress growth in MOLM-13 cells by recruiting the VHL E3 ubiquitin ligase. This PROTAC-based degrader leads to potent and selective degradation of TRIM24, causing apoptosis and a sustained proliferative defect.
- Potent and selective degradation of TRIM24
- Suppresses growth in MOLM-13 cells
- Induces apoptosis with enhanced PARP cleavage
- Based on PROTAC technology
Medchemexpress LLC HY-15868 50mg , HS-173 CAS:1276110-06-5 Purity:98%
Medchemexpress, HY-15868 50mg HS-173 CAS:1276110-06-5 Formula:C21H18N4O4S IC50: 0.8 nM (PI3Kα) Purity:98% HS-173 is a novel PI3K inhibitor, that is used for cancer treatment. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-100984 5mg Medchemexpress, HA-100 CAS:84468-24-6 Purity:>98%
Medchemexpress, HY-100984 5mg HA-100 CAS:84468-24-6 HA-100 is an inhibitor of cGMP-dependent protein kinase ( PKG ), cAMP-dependent protein kinase ( PKA ), protein kinase C ( PKC ) and MLC-kinase with IC 50 s of 4, 8, 12 and 240 μM, respectively [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.