Benzenesulfonamides

eMolecules​ N,N-Diethyl 3-borono-4-methylbenzenesulfonamide | 871329-80-5 | 5G | Purity: 97%

Combi-Blocks | N,N-Diethyl 3-borono-4-methylbenzenesulfonamide | 5G | 871329-80-5 | MFCD08056356

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Medchemexpress LLC Homo Sildenafil | 642928-07-2 | 99.3% | 50 MG

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Homo Sildenafil is an analog of Sildenafil that acts as a phosphodiesterase inhibitor. This product is for research use only, not for sale to patients or for medical applications.

• Molecular weight: 488.6
• Molecular formula: C23H32N6O4S
• Appearance: Solid, white to off-white
• Target: Phosphodiesterase (PDE)
• Storage for powder: -20°C for 3 years, 4°C for 2 years
• Storage in solvent: -80°C for 6 months, -20°C for 1 month
• Solubility: 50 mg/mL in DMSO (in vitro)

Medchemexpress LLC Vercirnon sodium | 886214-18-2 | 98.0% | 466.91 g/mol | C22H20ClN2NaO4S | 10 MG

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Vercirnon sodium is a selective, orally bioavailable antagonist of the chemokine receptor CCR9 supplied for research use. It is provided as a solid and as a DMSO solution for use in biochemical and cellular assays.

• Selective CCR9 antagonist for research applications.
• Available as solid forms and as a 10 mM solution in DMSO.
• High purity (~98.0%) suitable for analytical and pharmacological studies.
• Soluble in DMSO at 100 mg/mL; ultrasonic assistance recommended.
• Recommended storage: 4°C under inert gas; in solvent store at -80°C for long-term stability.

Medchemexpress LLC Orexin receptor antagonist 3 | 1293282-55-9 | 99.6% | 434.45 | 50 MG

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Orexin receptor antagonist 3 (example 216) is an orexin receptor antagonist, which is extracted from the patent WO2011050198A1. It is intended for research use only and not for sale to patients.

• Acts as an orexin receptor antagonist.
• Solid with an off-white to light yellow appearance.
• Solubility in DMSO is 33.33 mg/mL (76.72 mM).
• Storage recommendations include -20°C for 3 years as a powder, 4°C for 2 years as a powder, -80°C for 6 months in solvent, and -20°C for 1 month in solvent.

Medchemexpress LLC Bosentan hydrate | 157212-55-0 | 99.9% | C27H31N5O7S | 100 MG

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Bosentan hydrate is a competitive and dual antagonist of endothelin-1 (ET) for the ETA and ETB receptors, with Ki values of 4.7 nM and 95 nM in human SMC, respectively. It has a molecular weight of 569.63 g/mol.

• Competitive and dual antagonist of endothelin-1 (ET)
• Targets ETA and ETB receptors
• Ki of 4.7 nM for ETA and 95 nM for ETB in human SMC
• Store powder at -20°C for 3 years or 4°C for 2 years
• Store in solvent at -80°C for 2 years or -20°C for 1 year

Medchemexpress LLC 7-Methyl-1,5,7-triazabicyclo[4.4.0]dec-5-ene | 84030-20-6 | MFCD00043004 | 99.2% | C8H15N3 | 500 MG

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7-Methyl-1,5,7-triazabicyclo[4.4.0]dec-5-ene is a drug intermediate used for the synthesis of various active compounds. This product is intended for research use only.

• Purity: 99.2%
• Molecular weight: 153.23
• Chemical formula: C8H15N3
• CAS number: 84030-20-6
• Appearance: Liquid
• Color: Colorless to light yellow
• Storage conditions:
  • Pure form: -20°C for 3 years, 4°C for 2 years
  • In solvent: -80°C for 6 months, -20°C for 1 month

Medchemexpress LLC Fedratinib hydrochloride hydrate | 1374744-69-0 | MFCD28137677 | 99.9% | 615.62 g·mol⁻¹ | C27H40Cl2N6O4S | 5 MG

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Fedratinib hydrochloride hydrate is the hydrochloride hydrate salt of fedratinib, a selective, orally active, ATP-competitive JAK2 inhibitor used in preclinical research. The compound is supplied as a solid research reagent for studies of JAK2-driven signaling and cellular assays.

• Hydrochloride hydrate salt form for increased stability
• Selective ATP-competitive JAK2 inhibitor suitable for preclinical studies
• Molecular weight 615.62 g·mol⁻¹ and formula C27H40Cl2N6O4S
• High purity (≈99.9%) and solid, white to yellow appearance
• Offered in small research pack sizes for dosing and assay work
• Storage: 4°C sealed; in solvent, -80°C for long-term stability

Medchemexpress LLC YAP/TAZ inhibitor-1 | 2093565-23-0 | 99.7% | 621.81 | 10 MG

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YAP/TAZ inhibitor-1 is a YAP/TAZ inhibitor, extracted from patent WO2017058716A1, Compound 1. It has an IC50 of <0.100 μΜ in a firefly luciferase assay. As an inhibitor of transcriptional coactivator with PDZ binding motif/Yes-associated protein transcriptional coactivator (TAZ/YAP), it targets transcriptional co-activators of the Hippo pathway network, which regulate cell proliferation, migration, and apoptosis.

• Appearance: solid
• Color: off-white to yellow
• Shipping: room temperature in continental US; may vary elsewhere
• Storage (solid): 4°C, protect from light
• Storage (in solvent): -80°C for 6 months; -20°C for 1 month (protect from light)

Medchemexpress LLC 5-[6-methyl-5-[(1S,2R)-2-propan-2-ylcyclopropyl]pyridazin-3-yl]-1H-pyrimidine-2,4-dione | 2375815-63-5 | 99.9% | 286.33 g/mol | C15H18N4O2 | 5 MG

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CD73-IN-3 is a small-molecule CD73 inhibitor intended for preclinical cancer research and cell-based assays. It is supplied as a high-purity solid and has been characterized in human cell assays for potency and stability.

• Potent CD73 inhibition with IC50 = 7.3 nM in Calu6 human cell assay.
• High purity (99.89%) suitable for research applications.
• Solid, white to off-white physical form for easy handling and storage.
• Stable under recommended storage: powder -20°C (3 years), 4°C (2 years); in solvent -80°C (6 months), -20°C (1 month).
• Molecular formula C15H18N4O2 and molecular weight 286.33 g/mol for formulation planning.

Medchemexpress LLC N-Benzyl-N-Cbz-glycine | 76315-01-0 | MFCD02094473 | 265.31 | 5 G

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2-(Benzyl(tert-butoxycarbonyl)amino)acetic acid, also known as N-Benzyl-N-Cbz-glycine, is a derivative of Glycine. It is intended for research use only and is not sold to patients. Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances.

• Amino acid derivative
• Purity: 98.0%
• Physical appearance: solid, ranging from white to off-white
• Molecular weight: 265.31
• Formula: C14H19NO4
• Cas no.: 76315-01-0
• Storage conditions:
  • Powder: -20°c for 3 years, 4°c for 2 years
  • In solvent: -80°c for 6 months, -20°c for 1 month