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Filtered Search Results
Medchemexpress LLC GP130 receptor agonist-1 | 339303-87-6 | 100.0% | 50 MG
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GP130 receptor agonist-1 is a potent, brain-penetrant, orally active small-molecule agonist of the gp130 receptor with demonstrated neuroprotective activity against NMDA-induced neurotoxicity and modulation of STAT3, AKT, and ERK1/2 signaling in cellular and in vivo studies.
- Potent brain-penetrant gp130 receptor agonist.
- Orally active in preclinical dosing studies.
- Demonstrated neuroprotective effect against NMDA-induced neurotoxicity.
- Modulates STAT3, AKT, and ERK1/2 signaling pathways.
- Molecular formula C15H11FN2S, molecular weight ~270.32 g/mol.
- High purity (reported ~99.95%) and white to off-white solid appearance.
- Soluble in DMSO; in vivo formulation protocols provided for suspension or oil-based dosing.
- Store powder at -20°C for long-term stability; follow solvent storage recommendations for solutions.
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![Medchemexpress LLC N-[3-(1,3-benzothiazol-2-yl)-6-propan-2-yl-5,7-dihydro-4H-thieno[2,3-c]pyridin-2-yl]acetamide | 524708-03-0 | MFCD11984329 | 99.5% | C19H21N3OS2 | 10MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000261794.png-250.jpg)
Medchemexpress LLC N-[3-(1,3-benzothiazol-2-yl)-6-propan-2-yl-5,7-dihydro-4H-thieno[2,3-c]pyridin-2-yl]acetamide | 524708-03-0 | MFCD11984329 | 99.5% | C19H21N3OS2 | 10MG
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APE1-IN-1 (CAS 524708-03-0) is a small-molecule inhibitor of apurinic/apyrimidinic endonuclease 1 (APE1) that is reported to penetrate the blood-brain barrier and to inhibit APE1 activity in vitro (IC50 ≈ 2 μM). It is provided as a research reagent and has been used in cellular studies to increase the cytotoxicity of alkylating agents.
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Medchemexpress LLC HY-101270 5mg Medchemexpress, STK16-IN-1 CAS:1223001-53-3 Purity:>98%
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Medchemexpress, HY-101270 5mg STK16-IN-1 CAS:1223001-53-3 STK16-IN-1 is a STK16 kinase inhibitor with an IC 50 of 295 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules 1259929-80-0 | Ethyl 7-bromo-5-fluorobenzofuran-2-carboxylate | Apollo Scientific287.084 | C11H8BrFO3 | 95.000 | CCOC(=O)c1cc2cc(F)cc(Br)c2o1 | 1g | 562430763
Ethyl 7-bromo-5-fluorobenzofuran-2-carboxylate | Apollo Scientific | 1259929-80-0287.084 | C11H8BrFO3 | 95.000 | CCOC(=O)c1cc2cc(F)cc(Br)c2o1 | 1g | 562430763
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Medchemexpress LLC Enavogliflozin | 1415472-28-4 | 98.4% | 446.92 g·mol⁻¹ | C24H27ClO6 | 5 MG
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Enavogliflozin is an orally active, selective sodium-glucose cotransporter-2 (SGLT-2) inhibitor developed for treatment of type 2 diabetes and related metabolic disorders. The compound is provided to researchers as a solid powder and as concentrated solution formats for in vitro and translational studies, and it has been characterized in peer-reviewed studies and regulatory entries.
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STA Pharmaceutical Fmoc-D-2-Chloro-4-fluorophe | 100 g | CAS 1217680-33-5 | MDL MFCD12198165
Fmoc-D-2-Chloro-4-fluorophe is a Amino Acid reagent (Subcategory: Phe) sold by WuXi TIDES. Offered in 100 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 1217680-33-5
- MDL: MFCD12198165
- InChIKey: SPOFFSUHDCOUGW-JOCHJYFZSA-N
- Molecular Weight: 439.867
- Molecular Formula: C24H19ClFNO4
- Purity: ≥95%
- Container Type: 500 mL HDPE
- Pack Size: 100 g
- Net Weight: 100 g
- Gross Weight: 160.5 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: (R)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(2-chloro-4-fluorophenyl)propanoic acid
- SMILES: FC1=CC(Cl)=C(C[C@@H](NC(OCC2C3=CC=CC=C3C4=CC=CC=C42)=O)C(O)=O)C=C1
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Apexbio Technology LLC G-1(Synonyms: G1, G-1 agonist, GPER agonist G-1, GPR30 agonist G-1, GPER-selective agonist G-1), 10mg, CAS: 881639-98-1.
G-1 (CAS 881639-98-1) is a selective agonist for the G protein-coupled receptor GPR30 GPR30 an integral membrane receptor localized within the endoplasmic reticulum binds estradiol and aldosterone and activates various intracellular signaling cascades G-1 binds selectively to GPR30 with a Ki of approximately 11 nM while exhibiting minimal affinity to estrogen receptors ER and ER even at micromolar concentrations Activation of GPR30 by G-1 elevates intracellular calcium concentrations (EC50 2 nM) and induces PI3K-dependent nuclear accumulation of PIP3 In animal models G-1 treatment mitigates myocardial fibrosis modulates -adrenoceptor expression and improves cardiac function suggesting utility in cardiovascular and endocrine research
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eMolecules 2169316-15-6 | Medchem Express | SOCE inhibitor 1 | 5mg | 654841665 | HY-112913 | 513.477 | C25H22F3N5O4
Ambeed | (3R5S)-rel-35-Dimethylmorpholine | 100mg | 650570515 | A605643 | 45597-00-0 | MFCD12405010 | 115.176 | C6H13NO
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eMolecules 1630808-89-7 | Medchem Express | FT113 | 5mg | 482203956 | HY-111551 | 409.417 | C22H20FN3O4
Pharmablock | cis-cyclohexane-13-dicarboxylic acid | 100mg | 717426433 | PBTEN7815 | 2305-31-9 | MFCD01311240 | 172.180 | C8H12O4
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Medchemexpress LLC Kras inhibitor-10 | 2578876-75-0 | 99.9% | 519.63 | 50 MG
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KRAS inhibitor-10 is a tetrahydroisoquinoline compound that selectively and effectively inhibits RAS proteins, particularly KRAS proteins. It acts as an orally active anti-cancer agent, useful for various cancer research, including studies on pancreatic cancer, breast cancer, multiple myeloma, leukemia, and lung cancer.
- Selectively and effectively inhibits RAS proteins, particularly KRAS proteins
- Orally active anti-cancer agent
- Utilized for cancer research
- Exhibits antiproliferative effects in KRas mutant tumor cells
- Shows significant oral anti-tumor activities in vivo
- Safe and well-tolerated in bearing mice
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Medchemexpress LLC HY-18770A 5mg Medchemexpress, IDO-IN-6 CAS:1402837-76-6 Purity:>98%
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Medchemexpress, HY-18770A 5mg IDO-IN-6 CAS:1402837-76-6 IDO-IN-6 (NLG-1486) is an indoleamine 2,3-dioxygenase ( IDO ) inhibitor extracted from patent WO WO2012142237A1, Compound 1486, has an IC 50 of <1 μM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-112166 10mg Medchemexpress, PRN1008 CAS:1575596-29-0 Purity:>98%
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Medchemexpress, HY-112166 10mg PRN1008 CAS:1575596-29-0 PRN1008 is a reversible covalent, selective and oral active inhibitor of Bruton’s Tyrosine Kinase (BTK), with an IC50 of 1.3 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC GPR30 agonist-1 | 415919-74-3 | 98.6% | 374.25 | 50 MG
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GPR30 agonist-1 is a G protein-coupled receptor 30 (GPR30) agonist that exerts vasorelaxant effects.
- Induces a concentration-dependent relaxation in carotid arteries from both male and female rats.
- Relaxation is abolished by endothelium removal.
- Relaxation is abrogated in the presence of the nitric oxide synthase inhibitor NG-nitro-l-arginine methyl ester (100 μM).
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STA Pharmaceutical 1-Fmoc-4-(4-fluorophenyl)-4-carboxypiperidine | 50 g | CAS 1076197-06-2 | MDL MFCD11226817
1-Fmoc-4-(4-fluorophenyl)-4-carboxypiperidine is a Amino Acid reagent (Subcategory: Unusual AA) sold by WuXi TIDES. Offered in 50 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 1076197-06-2
- MDL: MFCD11226817
- InChIKey: DPGFVVPTWGNEHH-UHFFFAOYSA-N
- Molecular Weight: 445.49
- Molecular Formula: C27H24FNO4
- Purity: ≥95%
- Container Type: 250 mL HDPE
- Pack Size: 50 g
- Net Weight: 50 g
- Gross Weight: 89.8 g
- Commodity Code: 29333999
- Country Of Origin: China
- IUPAC: 1-(((9H-fluoren-9-yl)methoxy)carbonyl)-4-(4-fluorophenyl)piperidine-4-carboxylic acid
- SMILES: O=C(N1CCC(C2=CC=C(C=C2)F)(CC1)C(O)=O)OCC3C4=CC=CC=C4C5=CC=CC=C35
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eMolecules 1373393-48-6 | 2-Chloro-4,6-difluorobenzene boronic acid | Apollo Scientific | MFCD18415645 | 192.350 | C6H4BClF2O2 | 95.000 | OB(O)c1c(F)cc(F)cc1Cl | 1g | 562459273
2-Chloro-4,6-difluorobenzene boronic acid | Apollo Scientific | 1373393-48-6 | MFCD18415645 | 192.350 | C6H4BClF2O2 | 95.000 | OB(O)c1c(F)cc(F)cc1Cl | 1g | 562459273
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