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Filtered Search Results
eMolecules 1627710-50-2 | Medchem Express | LJH685 | 5mg | 446270128 | HY-19712 | MFCD29924738 | 381.427 | C22H21F2N3O
Medchem Express | Ki8751 | 10mg | 446260590 | HY-12038 | 228559-41-9 | MFCD09971092 | 469.420 | C24H18F3N3O4
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Medchemexpress LLC CYP3cide (PF-4981517) | 1390637-82-7 | 99.9% | 456.59 | 5 MG
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CYP3cide (PF-4981517) is a potent, selective, and time-dependent inhibitor of cytochrome P4503A4 (CYP3A4). It can be used to distinguish the contributions of CYP3A4 versus CYP3A5 on agent metabolism. The IC50 values for Midazolam 1'-hydroxylase activity are 0.03 μM, 17 μM, and 71 μM for CYP3A4, CYP3A5, and CYP3A7, respectively.
- Potent, selective, and time-dependent inhibitor of CYP3A4.
- Useful for distinguishing the roles of CYP3A4 and CYP3A5 in drug metabolism.
- Purity: 99.92%.
- Available in solid and solution forms.
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Selleck Chemical LLC Ibrolipim | 133208-93-2 | 451.2 g/mol | 5MG
Ibrolipim | 133208-93-2 | 451.2 g/mol | 5MG
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Medchemexpress LLC HY-103082 5mg Medchemexpress, CLK1-IN-1 CAS:2123491-32-5 Purity:>98%
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Medchemexpress, HY-103082 5mg CLK1-IN-1 CAS:2123491-32-5 CLK1-IN-1 is a potent and selective of Cdc2-like kinase 1 (CLK1) inhibitor, with an IC50 of 2 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-10247 10mg Medchemexpress, BRAF inhibitor CAS:918505-61-0 Purity:>98%
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Medchemexpress, HY-10247 10mg BRAF inhibitor CAS:918505-61-0 BRAF inhibitor is a B-Raf inhibitor extracted from patent WO/2011103196 A1, Compound P-0850. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC CMPD1 10MG
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CMPD1 is a selective and non-ATP-competitive p38 MAPK-mediated MK2 phosphorylation inhibitor with apparent Ki (Kiapp) of 330 nM., CAS 41179-33-3
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Selleck Chemical LLC HSP990
HSP990 (NVP-HSP990) is a novel potent and selective HSP90 inhibitor for HSP90 / with IC50 of 0 6 nM/0 8 nM NVP-HSP990 induces cell cycle arrest and apoptosis
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Medchemexpress LLC A-395 100Mg | HY-101512-100MG
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A-395 100Mg
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Medchemexpress LLC HY-12038 10mg Medchemexpress, Ki8751 CAS:228559-41-9 Purity:>98%
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Medchemexpress, HY-12038 10mg Ki8751 CAS:228559-41-9 Ki8751 is a potent VEGFR2 inhibitor with an IC50 of 0.9 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Selleck Chemical LLC Vericiguat-5mg
Vericiguat (BAY1021189, Verquvo) is a potent, orally available and soluble guanylate cyclase (sGC) stimulator.
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Medchemexpress LLC HY-U00197 1mg Medchemexpress, Tilmacoxib CAS:180200-68-4 Purity:>98%
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Medchemexpress, HY-U00197 1mg Tilmacoxib CAS:180200-68-4 Tilmacoxib (JTE522) is a highly selective, time-dependent and irreversible human COX-2 inhibitor with an IC50 of 85 nM in an enzyme assay. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Aurora Fine Chemicals 3-(3-FLUOROPHENYL)-1- 4-25MG
3-(3-fluorophenyl)-1-[4-[(6-imidazol-1-ylpyrimidin-4-yl)amino]phenyl]urea, 1360287-51-9
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Selleck Chemical LLC Paroxetine HCl 50mg 78246-49-8 BRL-29060A, FG-7051
Paroxetine HCl (BRL-29060A, FG-7051) is an antidepressant drug of the SSRI type. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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Medchemexpress LLC BAM(8-22) | 412961-36-5 | 99.89% | 1971.20 | 5 MG
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BAM(8-22), a proteolytically cleaved product of proenkephalin A and sensory neuron-specific receptor (SNSR) agonist, is a potent activator of Mas-related G-protein-coupled receptors (Mrgprs), specifically MrgprC11 and hMrgprX1. It induces scratching in mice in an Mrgpr-dependent manner. Additionally, BAM(8-22) has an analgesic effect and can inhibit the activation of microglia.
- Potent activator of Mas-related G-protein-coupled receptors (Mrgprs).
- Induces scratching in mice in an Mrgpr-dependent manner.
- Has an analgesic effect.
- Inhibits the activation of microglia.
- Increases miR-184 level in LPS-treated BV-2 cells.
- Reduces Iba-1 and inflammatory cytokines in LPS-treated BV-2 cells.
- Diminishes NMDA-evoked nocifensive behaviors and hyperalgesia in rat pain models.
- Reduces NMDA-evoked expression of FLI and NADPH reactivity in the spinal dorsal horn.
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Medchemexpress LLC (R)-1-(4-chloro-2-oxo-1,2-dihydropyridin-3-yl)-N-(4-methyl-3-(N-(3-pyridinylmethyl)sulfamoyl)phenyl)-2-pyrrolidinecarboxamide | 2760881-74-9 | 98.0% | C21H22ClN5O4S | 10MG
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BRD0639 is a first-in-class inhibitor of the PRMT5-substrate adaptor interaction that acts as a PRMT5 binding motif (PBM)-competitive agent for studying PBM-dependent PRMT5 activities. Supplied as a solid with analytical characterization, it is intended for research use in biochemical and cellular assays.
- PBM-competitive mechanism enables selective modulation of PRMT5 interactions.
- High reported purity appropriate for biochemical and cellular studies.
- Solid form with recommended cold storage for extended stability.
- Available in small research-scale packaging to support exploratory work.
- Documented chemical identifiers and characterization for traceability.
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