Fluorobenzenes

Organic compounds considered aryl halides that consist of a phenyl group with a fluorine atom substitution in the following structure: C₆H₅F.

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976 – 990 of 4,356 results

976

Medchemexpress LLC FC131 TFA | 842166-42-1 | 99.9% | 843.85 | 10 MG

FC131 TFA is a CXCR4 antagonist that inhibits [125I]-SDF-1 binding to CXCR4 with an IC50 of 4.5 nM. It also exhibits anti-HIV activity. It is for research use only and not sold to patients.

Inhibits [125I]-SDF-1 binding to CXCR4 with an IC50 of 4.5 nM
Exhibits anti-HIV activity
Appearance: solid
Color: white to off-white
Soluble in DMSO (100 mg/mL)

Pricing & Availability

977

Medchemexpress LLC DX600 | 478188-26-0 | 99.7% | 3074.33 | 10 MG

DX600 is a selective ACE2 specific inhibitor with a K_D of 1.3 nM, and it does not cross-react with ACE. It exacerbates diabetes-induced cardiovascular dysfunction and increases cardiac and renal NOX activity.

Inhibits rhACE2 activity
Decreases NR 8383 cell growth and increases TNF-a and IL-6 content in the supernatant
Exacerbates diabetes-induced cardiovascular dysfunction in Streptozotocin-treated diabetic rats
Increases thrombus weight in a thrombosis model in rats

Pricing & Availability

978

Medchemexpress LLC BA 1 TFA | 99.4% | 1247.32 | 5 MG

BA 1 TFA is a potent agonist for the bombesin (BB) family of receptors. It binds with high affinity to Bombesin receptor subtype-3 (BRS3), gastrin releasing peptide receptor (GRPR), and neuromedin B receptor (NMBR) with IC50s of 6, 0.4, and 2.5 nM respectively. BA1 (0.1 μM) significantly increases FAK tyrosine phosphorylation in BRS-3 transfected NCI-H1299 cells.

Potent agonist for bombesin (BB) family of receptors
Binds with high affinity to BRS3 (IC50 6 nM)
Binds with high affinity to GRPR (IC50 0.4 nM)
Binds with high affinity to NMBR (IC50 2.5 nM)
Significantly increases FAK tyrosine phosphorylation in BRS-3 transfected NCI-H1299 cells

Pricing & Availability

979

Medchemexpress LLC N-(4-chloro-3-nitrophenyl)-4-nitro-2,1,3-benzoxadiazol-5-amine | 313964-19-1 | 99.9% | 335.66 g/mol | C12H6ClN5O5 | 10 MG

HIF-2α-IN-3 is a small-molecule allosteric inhibitor of hypoxia-inducible factor-2α (HIF-2α) used as a research reagent in studies of hypoxia signaling and oncology. Reported biochemical activity includes an IC50 of 0.4 μM and a KD of 1.1 μM; the compound is supplied as a high-purity solid for laboratory use.

Allosteric HIF-2α inhibition with reported IC50 0.4 μM and KD 1.1 μM.
Suitable for in vitro studies of hypoxia signaling and cancer biology.
High purity suitable for research applications.
Supplied as a light yellow solid for standard laboratory handling.

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980

Medchemexpress LLC NELOCIGUAT 10 mg

NELOCIGUAT 10MG

Pricing & Availability

981

Medchemexpress LLC OD36 | 1638644-62-8 | 99.3% | 330.77 | 5 MG

OD36 | 1638644-62-8 | 99.3% | 330.77 | 5 MG

Pricing & Availability

982

Medchemexpress LLC F-15599 tosylate (NLX-101 tosylate) | 955112-72-8 | 567.05 | 100 MG

F-15599 tosylate is a highly selective G-protein biased 5-HT1A receptor agonist, with a Ki of 3.4 nM. It is intended for research use only.

Highly selective G-protein biased 5-HT1A receptor agonist
Ki of 3.4 nM
Related to neurological, eye or ear disease research
Can be found in compound screening libraries

Pricing & Availability

983

Medchemexpress LLC DAA-1106 | 220551-92-8 | 99.9% | 395.42 | 100 MG

DAA1106 is a peripheral benzodiazepine receptor (PBR) agonist that is permeable to the blood-brain barrier, but has no affinity for GABAA receptors.

Acts as a peripheral benzodiazepine receptor agonist
Permeable to the blood-brain barrier
No affinity for GABAA receptors

Pricing & Availability

984

Medchemexpress LLC Sodium 2-(3-(2,6-difluoro-4-(1H-pyrazol-4-yl)phenyl)-3-oxoprop-1-en-1-yl)-4-(1-methyl-1H-pyrazol-4-yl | 2519537-70-1 | 98.9% | 50 MG

HOIPIN-8 is a research small-molecule inhibitor of the linear ubiquitin chain assembly complex (LUBAC) used to probe ubiquitination and NF-κB signaling in biochemical and cell-based studies. It is supplied as a sodium salt with a molecular weight of 456.38 g/mol.

Molecular weight 456.38 g/mol
Molecular formula C23H15F2N4NaO3
Potent LUBAC inhibitor with IC50 of 11 nM
Soluble in DMSO at 50 mg/mL and formulatable for in vivo dosing
Store sealed at -20°C; in solution store at -80°C for long-term stability
Suitable for biochemical assays and cell-based research

Pricing & Availability

985

Medchemexpress LLC 2-(((r)-3-(chlorophenyl)-1-((r)-1-hydroxypropan-2-yl)sulfonyl)-1-(2-hydroxypropan-2-yl)piperidin-4-yl)methanamine | 1838123-21-9 | 99.5% | 100MG

2-(((r)-3-(chlorophenyl)-1-((r)-1-hydroxypropan-2-yl)sulfonyl)-1-(2-hydroxypropan-2-yl)piperidin-4-yl)methanamine | 1838123-21-9 | 99.5% | 100MG

Pricing & Availability

986

Medchemexpress LLC (Rac)-MEM 1003 | 165187-25-7 | 99.6% | 5MG

(Rac)-MEM 1003 | 165187-25-7 | 99.6% | 5MG

Pricing & Availability

987

Medchemexpress LLC RORT INVERSE AGONIS 100 mg

RORT INVERSE AGONIS 100MG

Pricing & Availability

988

Medchemexpress LLC AHR ANTAGONIST 2 50 mg

AHR ANTAGONIST 2 50MG

Pricing & Availability

989

Medchemexpress LLC Elabela(19-32) (TFA) | 98.8% | 1821.05 | 5 MG

Elabela(19-32) TFA is an active fragment of ELABELA (ELA) that binds to the apelin receptor (APJ). It activates the Gαi1 and β-arrestin-2 signaling pathways, induces receptor internalization, and has demonstrated effects on cardiovascular function, including reducing arterial pressure and exerting positive inotropic effects on the heart.

Binds to apelin receptor (APJ)
Activates Gαi1 and β-arrestin-2 signaling pathways with EC50s of 8.6 nM and 166 nM, respectively
Induces receptor internalization with an EC50 of 36 nM in HEK293 cells
Reduces arterial pressure
Exerts positive inotropic effects on the heart
Has a Ki of 0.93 nM for binding of radioligand apelin-13[Glp65, Nle75, Tyr77][125I]
Rapidly metabolized in rat plasma (t1/2<2 min)

Pricing & Availability

990

Medchemexpress LLC BAM(8-22) | 412961-36-5 | 99.89% | 1971.20 | 5 MG

BAM(8-22), a proteolytically cleaved product of proenkephalin A and sensory neuron-specific receptor (SNSR) agonist, is a potent activator of Mas-related G-protein-coupled receptors (Mrgprs), specifically MrgprC11 and hMrgprX1. It induces scratching in mice in an Mrgpr-dependent manner. Additionally, BAM(8-22) has an analgesic effect and can inhibit the activation of microglia.

Potent activator of Mas-related G-protein-coupled receptors (Mrgprs).
Induces scratching in mice in an Mrgpr-dependent manner.
Has an analgesic effect.
Inhibits the activation of microglia.
Increases miR-184 level in LPS-treated BV-2 cells.
Reduces Iba-1 and inflammatory cytokines in LPS-treated BV-2 cells.
Diminishes NMDA-evoked nocifensive behaviors and hyperalgesia in rat pain models.
Reduces NMDA-evoked expression of FLI and NADPH reactivity in the spinal dorsal horn.

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Fluorobenzenes

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Medchemexpress LLC FC131 TFA | 842166-42-1 | 99.9% | 843.85 | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC DX600 | 478188-26-0 | 99.7% | 3074.33 | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC BA 1 TFA | 99.4% | 1247.32 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC N-(4-chloro-3-nitrophenyl)-4-nitro-2,1,3-benzoxadiazol-5-amine | 313964-19-1 | 99.9% | 335.66 g/mol | C12H6ClN5O5 | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC NELOCIGUAT 10 mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC OD36 | 1638644-62-8 | 99.3% | 330.77 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC F-15599 tosylate (NLX-101 tosylate) | 955112-72-8 | 567.05 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC DAA-1106 | 220551-92-8 | 99.9% | 395.42 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Sodium 2-(3-(2,6-difluoro-4-(1H-pyrazol-4-yl)phenyl)-3-oxoprop-1-en-1-yl)-4-(1-methyl-1H-pyrazol-4-yl | 2519537-70-1 | 98.9% | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 2-(((r)-3-(chlorophenyl)-1-((r)-1-hydroxypropan-2-yl)sulfonyl)-1-(2-hydroxypropan-2-yl)piperidin-4-yl)methanamine | 1838123-21-9 | 99.5% | 100MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC (Rac)-MEM 1003 | 165187-25-7 | 99.6% | 5MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC RORT INVERSE AGONIS 100 mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC AHR ANTAGONIST 2 50 mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Elabela(19-32) (TFA) | 98.8% | 1821.05 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC BAM(8-22) | 412961-36-5 | 99.89% | 1971.20 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More