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Filtered Search Results
Medchemexpress LLC 4,5-Dimethoxybenzene-1,2-diamine | 27841-33-4 | 97.9% | C8H12N2O2 | 50 MG
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4,5-Dimethoxybenzene-1,2-diamine can be used as a standard for the determination of methyldiacetaldehyde, an intermediate product of glycolysis and a diabetic ketone biomarker of acidosis.
- Can be used as a standard for the determination of methyldiacetaldehyde.
- Functions as an intermediate product of glycolysis.
- Serves as a diabetic ketone biomarker of acidosis.
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Medchemexpress LLC L-371,257 | 162042-44-6 | 99.34 % | 507.58 | 100 MG
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L-371,257 is an orally bioavailable, non-blood-brain barrier penetrant compound that functions as a selective and competitive antagonist of the oxytocin receptor. It exhibits high affinity for both the oxytocin receptor (Ki=19 nM) and the vasopressin V1a receptor (Ki=3.7 nM).
- Orally bioavailable
- Non-blood-brain barrier penetrant
- Selective and competitive oxytocin receptor antagonist (pA2=8.4)
- High affinity for oxytocin receptor (Ki=19 nM)
- High affinity for vasopressin V1a receptor (Ki=3.7 nM)
- Stimulates weight gain in rat models
- Exhibits activity at human oxytocin receptor in CHO cells (EC50 = 4.6 nM)
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eMolecules 2242464-44-2 | Medchem Express | BAY 2416964 | 5mg | 527574132 | HY-135829 | 387.82 | C18H18ClN5O3
ChemScene | (S)-1-(4-(tert-Butyl)phenyl)ethan-1-amine | 100mg | 569143593 | CS-0000313 | 511256-37-4 | MFCD06762044 | 177.291 | C12H19N
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eMolecules 1448316-08-2 | Medchem Express | BAY-826 | 5mg | 532149590 | HY-100756 | 558.53 | C26H19F5N6OS
Medchem Express | Dihydromethysticin | 1mg | 599423828 | HY-N0921 | 19902-91-1 | MFCD00221731 | 276.288 | C15H16O5
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Medchemexpress LLC HY-109096 10mg Medchemexpress, Nidufexor CAS:1773489-72-7 Purity:>98%
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Medchemexpress, HY-109096 10mg Nidufexor CAS:1773489-72-7 Nidufexor is a farnesoid X receptor (FXR) agonist. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Rocaglamide | 84573-16-0 | 505.56 | 50 MG
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Rocaglamide is isolated from the genus Aglaia and can be used for coughs, injuries, asthma, and inflammatory skin diseases. It is a potent inhibitor of NF-κB activation in T-cells and a selective heat shock factor 1 (HSF1) activation inhibitor with an IC50 of ~50 nM. Rocaglamide also inhibits the function of the translation initiation factor eIF4A and exhibits anticancer properties in leukemia.
- Isolated from the genus Aglaia.
- Can be used for coughs, injuries, asthma, and inflammatory skin diseases.
- Potent inhibitor of NF-κB activation in T-cells.
- Potent and selective heat shock factor 1 (HSF1) activation inhibitor.
- Inhibits the function of the translation initiation factor eIF4A.
- Has anticancer properties in leukemia.
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Medchemexpress LLC HY-N0693 10mg Medchemexpress, Schisandrin A CAS:61281-38-7 Purity:>98%
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Medchemexpress, HY-N0693 10mg Schisandrin A CAS:61281-38-7 Schisandrin A inhibits CYP3A activity with an IC 50 of 6.60 μM and K i of 5.83 μM, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules 1527503-11-2 | Medchem Express | A-366 | 5mg | 446261511 | HY-12583 | MFCD28133403 | 329.444 | C19H27N3O2
Ambeed | 25-Di(thiophen-2-yl)thieno[32-b]thiophene | 250mg | 586036433 | A703648 | 21210-90-2 | MFCD11114556 | 304.460 | C14H8S4
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Medchemexpress LLC PND-1186 hydrochloride | 1356154-94-3 | 99.9% | 537.96 | 50 MG
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PND-1186 hydrochloride is a potent, highly-specific, and reversible inhibitor of FAK with an IC50 of 1.5 nM. It selectively promotes tumor cell apoptosis.
- Potent, highly-specific, and reversible FAK inhibitor.
- IC50 of 1.5 nM for FAK.
- Selectively promotes tumor cell apoptosis.
- Inhibits FAK Tyr-397 phosphorylation in breast carcinoma cells.
- Reduces tumor growth by inducing apoptosis in vivo.
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Selleck Chemical LLC 4.4-Dimethoxybenzil S5310-25mg
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4 4 -Dimethoxybenzil (p-Anisil) is a biochemical that has been reported to have mesomorphic properties of a substituted bis(dithiolene)nickel complex derived from 4 4 -dimethoxybenzil
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Medchemexpress LLC MD2-TLR4-IN-1 | 2249801-12-3 | 98.2% | 10 MG
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MD2-TLR4-IN-1 is a myeloid differentiation protein 2/toll-like receptor 4 (MD2-TLR4) complex antagonist. It inhibits Lipopolysaccharides (LPS)-induced expression of TNF-α and IL-6 in macrophages with IC50 values of 0.89 μM and 0.53 μM, respectively. This compound can be utilized for the study of acute lung injury (ALI).
- Exerts anti-inflammatory activity by inhibiting NF-κB in RAW264.7 macrophages.
- Directly binds to the MD2-TLR4 complex and disrupts MD2-TLR4 activation.
- Suppresses NF-κB p65 subunit nuclear levels in LPS-induced macrophages.
- Significantly inhibits macrophage infiltration and ameliorates histopathological changes in lung tissues.
- Effectively reduces airspace inflammation and amends pulmonary lobule tissue structure.
- Decreases LPS-induced myeloperoxidase (MPO) activity and serum TNF-α levels.
- Reduces mRNA levels of TNF-α, IL-6, IL-1β, IL-12, IL-33, and COX-2 in lung tissues.
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Medchemexpress LLC HY-101285 100mg Medchemexpress, DMU2139 CAS:1821143-80-9 Purity:>98%
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Medchemexpress, HY-101285 100mg DMU2139 CAS:1821143-80-9 DMU2139 is a potent and specific CYP1B1 inhibitor, with IC 50 s of 9 nM and 795 nM for CYP1B1 and CYP1A1, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Risarestat (CT 112) | 79714-31-1 | 98.0% | 323.41 | 100 MG
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Risarestat (CT-112) is an aldose reductase inhibitor developed for the treatment of diabetic complications. It inhibits the accumulation of dulcitol in a dose-dependent manner and shows intraocular penetration following topical instillation.
- Inhibits accumulation of dulcitol
- Shows intraocular penetration
- Significantly decreases the anterior surface area of superficial corneal cells
- Improves corneal sensitivity in diabetic patients
- Increases blink response in galactose-fed rats
- Solid with a white to light yellow appearance
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Apexbio Technology LLC PND-1186 10MM IN 1ML DMSO
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PND-1186 10MM IN 1ML DMSO APEXBIO TECHNOLOGIES
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Medchemexpress LLC Kras G12c inhibitor 15 | 2349393-21-9 | 98.5% | 498.91 | C25H21ClF2N4O3 | 25MG
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KRAS G12C inhibitor 15 is a research-grade small-molecule inhibitor of the oncogenic KRAS G12C mutant. It was reported in patent WO2019110751A1 (compound 22) and shows potent biochemical activity; supplied as a solid for laboratory research only - consult the SDS and COA for handling and storage.
- Potent KRAS G12C inhibition (IC50 ≈ 5 nM).
- High purity (98.5%).
- Molecular formula C25H21ClF2N4O3.
- Molecular weight 498.91 g/mol.
- Appearance solid, white to yellow.
- Storage: protect from light and store under nitrogen; in solvent -80°C (6 months) or -20°C (1 month).
- Available as solid and as 10 mM solutions in DMSO; common pack sizes up to 100 mg.
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