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Filtered Search Results
eMolecules Medchem Express / Etrasimod / 5mg / 446261796 / HY-12789 / / 1206123-37-6 / MFCD28502134 / 457.493 / C26H26F3NO3
Medchem Express / Etrasimod / 5mg / 446261796 / HY-12789 / / 1206123-37-6 / MFCD28502134 / 457.493 / C26H26F3NO3
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Medchemexpress LLC Orm-10962 | 763926-98-3 | MFCD32067938 | 99.5% | 459.54 g/mol | C27H29N3O4 | 50MG
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ORM-10962 is a potent, highly selective inhibitor of the sodium-calcium exchanger (NCX) used for research into cardiac electrophysiology and cellular calcium handling. It inhibits NCX in both reverse and forward modes with low-nanomolar potency and is supplied as a light yellow solid with high reported purity.
- Potent NCX inhibition (IC50 ~55-67 nM).
- High reported purity (>99%).
- Good solubility in DMSO (≈250 mg/mL).
- Supplied as a light yellow solid for solid-sample handling.
- Storage-stable when kept frozen as recommended.
- Suitable for electrophysiology and cellular assays investigating NCX function.
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Medchemexpress LLC TP-004 | 1454299-21-8 | 99.2% | 50 MG
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TP-004 is a small-molecule chemical probe that potently and reversibly inhibits methionine aminopeptidase 2 (MetAP2) with an IC50 of 6 nM. It is supplied as a high-purity research-grade compound for biochemical and cellular studies.
- Potent, reversible MetAP2 inhibitor (IC50 6 nM).
- High purity: 99.2%.
- Molecular weight 363.34 g/mol; formula C17H16F3N5O.
- Supplied as a 50 mg research pack suitable for assay and probe development.
- Intended for research use only; not for human or veterinary use.
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eMolecules Medchem Express / TAK-593 / 5mg / 446265822 / HY-15506 / / 1005780-62-0 / MFCD23160045 / 445.483 / C23H23N7O3
Medchem Express / TAK-593 / 5mg / 446265822 / HY-15506 / / 1005780-62-0 / MFCD23160045 / 445.483 / C23H23N7O3
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Medchemexpress LLC Benzene, 1,4-dimethoxy-d10 | 74079-00-8 | 99.6% | 148.23 g·mol⁻1 | C8D10O2 | 10 MG
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1,4-Dimethoxybenzene-d10 is the deuterium-labeled isotopologue of 1,4-dimethoxybenzene supplied for analytical and research use as a tracer or internal standard. It is characterized by high isotopic incorporation and is intended for quantitative and qualitative analyses where a mass- or NMR-resolved labelled analog is required.
- Deuterium-labeled internal standard for quantitative analysis.
- High isotopic enrichment (~99.6% atom D) for reliable tracing.
- Suitable for NMR, GC-MS, and LC-MS applications.
- Available in multiple small-scale packaging sizes for analytical work.
- Provided with batch-specific certificate of analysis for traceability.
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Selleck Chemical LLC Phenoxybenzamine HCl S2499-1g
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Phenoxybenzamine HCl (NSC 37448 NCI-c01661) is a non-specific irreversible alpha antagonist with an IC50 of 550 nM
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Medchemexpress LLC Ly367385 hydrochloride | 2829282-00-8 | 99.4% | 245.66 | C10H12ClNO4 | 100 MG
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LY367385 hydrochloride is a selective and potent antagonist of the metabotropic glutamate receptor mGluR1a used in research to investigate mGluR1-mediated signaling, neuroprotective mechanisms, and seizure models. The compound is supplied as a solid suitable for laboratory handling and storage.
- Selective mGluR1a antagonist for receptor-specific studies.
- High reported purity supports reproducible results.
- Solid, stable form suitable for standard laboratory storage.
- Applicable to neuroprotection, anticonvulsant, and antiepileptic research.
- Compatible with common solvent storage conditions for short- and long-term use.
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eMolecules 3-(3-Phenyl-1,2,4-oxadiazol-5-yl)propanoic acid | 24088-59-3 | MFCD05130956 | 25g
Combi-Blocks | 3-(3-Phenyl-1,2,4-oxadiazol-5-yl)propanoic acid | 25g | 448006844 | QB-3090 | 95.000 | 24088-59-3 | MFCD05130956 | 218.212 | C11H10N2O3
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CHEM SERVICE INC ALDOL 3-HYDROXYBUTANAL 100MG
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NC2329046 ALDOL 3-HYDROXYBUTANAL 100MG
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eMolecules Medchem Express / NMS-E973 / 5mg / 572596915 / HY-17547 / / 1253584-84-7 / MFCD28099810 / 454.439 / C22H22N4O7
Medchem Express / NMS-E973 / 5mg / 572596915 / HY-17547 / / 1253584-84-7 / MFCD28099810 / 454.439 / C22H22N4O7
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Apexbio Technology LLC Tamoxifen Citrate 54965-24-1 5g
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Tamoxifen Citrate (CAS 54965-24-1) is a small-molecule antagonist targeting estrogen receptors (ER) It is designed to competitively bind ER thereby modulating estrogen-mediated signal transduction Tamoxifen Citrate exerts its biological activity primarily by inhibiting the transcriptional activity of estrogen-responsive genes leading to reduced synthesis of factors related to cell growth and angiogenesis In in vitro studies Tamoxifen Citrate demonstrates inhibition of cell proliferation with reported IC50 values typically ranging from 3 to 7 M depending on cell line and experimental conditions Based on these pharmacological properties Tamoxifen Citrate holds research potential in studies of estrogen receptor-dependent signaling pathways and anti-tumor strategies particularly in breast cancer models
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Medchemexpress LLC 1,4-dimethoxybenzene (standard) | 150-78-7 | MFCD00008401 | 100.0% | 138.16 g/mol | C8H10O2 | 250 MG
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1,4-dimethoxybenzene (standard) is an analytical reference material of 1,4-dimethoxybenzene (CAS 150-78-7) intended for research and analytical applications. It is supplied at very high purity for use in method development, calibration, and quantitative analysis in laboratory settings.
- Provides high-purity reference material for analytical assays.
- Suitable for chromatography and mass spectrometry calibration.
- Available in multiple pack sizes to suit laboratory needs.
- Supplied with safety data documentation for safe handling and use.
- Intended for research, method development, and quality control applications.
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eMolecules 3-Methoxy-5-methylpyrazin-2-amine | 89464-87-9 | MFCD09750038 | 1g
Combi-Blocks, Inc. | 3-Methoxy-5-methylpyrazin-2-amine | 1g | 569293461 | QP-7071 | 98.000 | 89464-87-9 | MFCD09750038 | 139.158 | C6H9N3O
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eMolecules 4-(Ethoxymethylthio)phenylboronic acid | 2096331-89-2 | MFCD19237160 | 1g
Combi-Blocks | 4-(Ethoxymethylthio)phenylboronic acid | 1g | 117523332 | BB-4003 | 98.000 | 2096331-89-2 | MFCD19237160 | 212.070 | C9H13BO3S
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Medchemexpress LLC Apabetalone | 1044870-39-4 | 99.34% | 370.40 | 100 MG
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Apabetalone (RVX-208) is an inhibitor of BET transcriptional regulators, specifically targeting the second bromodomain (BD2) with high selectivity. It enhances the production of ApoA-I in hepatocytes, leading to an increase in high-density lipoprotein cholesterol (HDL-C). Its mechanism involves binding to bromodomains of the BET family by competing for acetylated lysine binding sites. This epigenetic modulation of ApoA-I production suggests it as a potential therapeutic agent for atherosclerosis.
- Selective BET transcriptional regulator inhibitor
- Targets the second bromodomain (BD2)
- Increases ApoA-I production in liver cells
- Elevates high-density lipoprotein cholesterol (HDL-C)
- Acts via an epigenetic mechanism
- Investigated for atherosclerosis treatment
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