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Filtered Search Results
Medchemexpress LLC Tcmdc-135051 hydrochloride | 2705545-47-5 | 98.2% | 508.05 | C29H34ClN3O3 | 100MG
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TCMDC-135051 hydrochloride is the hydrochloride salt of TCMDC-135051, a selective and potent inhibitor of Plasmodium falciparum cyclin-dependent-like kinase 3 (PfCLK3) intended for research use in biochemical and cellular studies.
- selective PfCLK3 inhibition with low off-target toxicity.
- high purity suitable for research applications.
- light yellow to yellow solid form for easy handling.
- stable when stored sealed and protected from moisture.
- provided in small quantities for assay development and screening.
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Medchemexpress LLC HY-103015 1mg Medchemexpress, WZ4141 CAS:1222776-76-2 Purity:>98%
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Medchemexpress, HY-103015 1mg WZ4141 CAS:1222776-76-2 WZ4141 is an API intermediate. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Apexbio Technology LLC Diethylmaleate 141-05-9 100mg
Diethylmaleate (141-05-9) is a small-molecule compound that depletes intracellular glutathione (GSH) modulating cellular redox-sensitive pathways Diethylmaleate exerts its biological activity primarily through induction of oxidative stress and ROS generation leading to modulation of cell cycle apoptosis gene expression and activation of MAPK signaling pathways In vitro studies demonstrate that Diethylmaleate-mediated GSH depletion triggers cell cycle arrest and apoptosis Animal research shows effects on reproductive systems including altered testicular antioxidant status and sperm parameters Based on these pharmacological properties Diethylmaleate holds research potential in studies of oxidative stress redox regulation and toxicology
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Medchemexpress LLC HY-10398 5mg Medchemexpress, CTS-1027 CAS:193022-04-7 Purity:>98%
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Medchemexpress, HY-10398 5mg CTS-1027 CAS:193022-04-7 CTS-1027 is a potent small molecule inhibitor of MMPs, with IC50s of 0.3 nM, 0.5 nM for MMP2, MMP13, respectively, and has > 1,000 fold selectivity over MMP1. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-119039 10mg Medchemexpress, RU-301 CAS:1110873-99-8 Purity:>98%
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Medchemexpress, HY-119039 10mg RU-301 CAS:1110873-99-8 RU-301 is a pan-TAM receptor inhibitor, exerts pan-TAM inhibitory activity by binding at the interface between Gas6 and the Ig1 domain of the respective TAMs with Kd and IC50 values of 12 μM and 10 μM, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Aobchem 4 -Phenoxy-[1 1 -biphenyl]-4-carbaldehyde | 95% | CAS 1406541-79-4 | C19H14O2 | 1g
4 -Phenoxy-[1 1 -biphenyl]-4-carbaldehyde | 95% | CAS 1406541-79-4 | C19H14O2 | 1g
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eMolecules 19848-54-5 | 2-Hydrazino-3-methylpyrazine | Apollo Scientific | MFCD19201409 | 124.147 | C5H8N4 | 95.000 | Cc1nccnc1NN | 1g | 562446294
2-Hydrazino-3-methylpyrazine | Apollo Scientific | 19848-54-5 | MFCD19201409 | 124.147 | C5H8N4 | 95.000 | Cc1nccnc1NN | 1g | 562446294
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eMolecules 1013750-77-0 | Medchem Express | ML-030 | 5mg | 446257942 | HY-103050 | 412.46 | C20H20N4O4S
Ambeed | 2-(4455-Tetramethyl-132-dioxaborolan-2-yl)-9H-fluoren-9-one | 250mg | 696731920 | A334841 | 1021306-45-5 | MFCD16294551 | 306.170 | C19H19BO3
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eMolecules 63302-99-8 | Medchem Express | Azaphen (dihydrochloride monohydrate) | 100mg | 446271701 | HY-A0022A | MFCD00220368 | 388.29 | C16H23Cl2N5O2
Medchem Express | Azaphen (dihydrochloride monohydrate) | 100mg | 446271701 | HY-A0022A | 63302-99-8 | MFCD00220368 | 388.290 | C16H23Cl2N5O2
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Medchemexpress LLC 2-Thiophenemethanamine, N-[(4-chloro-2-methylphenyl)methyl]-N-[(4-chlorophenyl)methyl]-5-nitro- (hydrochloride) | 98.5% | 457.80 | 10 MG
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GSK2945 hydrochloride is a tertiary amine, and is a highly specific Rev-erbα/REV-ERBα (mouse/human reverse erythroblastosis virus α) antagonist with EC50s of 21.5 μM and 20.8 μM, respectively. GSK2945 hydrochloride enhances cholesterol 7α-hydroxylase (CYP7A1) level and cholesterol metabolism. It is intended for research use only and is not sold to patients.
- Highly specific Rev-erbα/REV-ERBα antagonist
- Enhances cholesterol 7α-hydroxylase (CYP7A1) level
- Promotes cholesterol metabolism
- Increases the transcriptional activity of Rev-erbα
- Upregulates Lrh-1/LRH-1 mRNA and protein
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Medchemexpress LLC GNE-371 | 1926986-36-8 | 98.1% | 431.49 | 10 MG
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GNE-371 is a potent and selective chemical probe for the second bromodomains of human transcription-initiation-factor TFIID subunit 1 and transcription-initiation-factor TFIID subunit 1-like. It binds TAF1(2) with an IC50 of 10 nM, showing excellent selectivity over other bromodomain-family members. It is also active in a cellular TAF1(2) target-engagement assay (IC50=38 nM) and demonstrates anti-proliferative synergy with the BET inhibitor JQ1, supporting its use in mechanistic and target-validation studies.
- Potent and selective chemical probe for the second bromodomains of human transcription-initiation-factor TFIID subunit 1 and transcription-initiation-factor TFIID subunit 1-like.
- IC50 of 10 nM for TAF1(2).
- Active in a cellular TAF1(2) target-engagement assay (IC50=38 nM).
- Exhibits anti-proliferative synergy with the BET inhibitor JQ1.
- Appearance: Solid, white to off-white.
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Medchemexpress LLC HY-15010 5mg Medchemexpress, L-371,257 CAS:162042-44-6 Purity:>98%
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Medchemexpress, HY-15010 5mg L-371,257 CAS:162042-44-6 L-371,257 is an orally bioavailable, non-blood-brain barrier penetrant, selective and competitive antagonist of oxytocin receptor (pA2=8.4) with high affinity at both the oxytocin receptor ( K i =19 nM) and vasopressin V1a receptor ( K i =3.7 nM) [1] [2] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Lyp-1 tfa | 99.52% | 1106.16 | 5 MG
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LyP-1 TFA is a cyclic 9 amino acids tumor homing peptide that selectively binds to p32 receptors which are overexpressed in various tumor-associated cells. For research use only, not for sale to patients.
- Shows a remarkable reduction in plaque formation and plaque occupation rates in the LyP-1-treated group (in vivo studies).
- Higher apoptotic rate in macrophages released from hypoxic plaques observed after LyP-1 treatment compared to control peptide (in vivo studies).
- Can be labeled with a near-infrared fluorophore (Cy5.5) for optical imaging.
- Exhibits lymphatics-specific binding.
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Medchemexpress LLC Bambuterol-d9 hydrochloride | 1794810-59-5 | 99.88% | 412.96 | 1 MG
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Bambuterol-d9 (hydrochloride) is the deuterium labeled Bambuterol. Bambuterol ((±)-Bambuterol) hydrochloride is a long-acting beta-adrenoceptor agonist (LABA) used in the treatment of asthma, and it is also a prodrug of terbutaline.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process.
- Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
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Medchemexpress LLC HY-103483 5mg Medchemexpress, MD2-IN-1 CAS:111797-22-9 Purity:>98%
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Medchemexpress, HY-103483 5mg MD2-IN-1 CAS:111797-22-9 MD2-IN-1 is an inhibitor of Myeloid differentiation protein 2 (MD2) with a KD of 189 μM for the recombinant human MD2 (rhMD2). Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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