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Filtered Search Results
Medchemexpress LLC PND-1186 hydrochloride | 1356154-94-3 | 99.9% | 537.96 | 50 MG
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PND-1186 hydrochloride is a potent, highly-specific, and reversible inhibitor of FAK with an IC50 of 1.5 nM. It selectively promotes tumor cell apoptosis.
- Potent, highly-specific, and reversible FAK inhibitor.
- IC50 of 1.5 nM for FAK.
- Selectively promotes tumor cell apoptosis.
- Inhibits FAK Tyr-397 phosphorylation in breast carcinoma cells.
- Reduces tumor growth by inducing apoptosis in vivo.
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eMolecules Maytansinoid | 57103-68-1 | | 100mg
Broadpharm | Maytansinoid | 100mg | 347153794 | BP-23647 | 98.000 | 57103-68-1 | | 565.060 | C28H37ClN2O8
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Medchemexpress LLC 5-methyl-7-methoxyisoflavone | 82517-12-2 | MFCD03093036 | 99.1% | 266.29 | C17H14O3 | 10 MG
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5-methyl-7-methoxyisoflavone is a non-steroidal isoflavone used in research for its aromatase inhibitory and antioxidant properties; it has reported remyelinating activity and NF-κB inhibitory effects and is supplied in solid and DMSO solution formats for biochemical and cellular studies.
- isoflavone scaffold with aromatase inhibitory activity.
- Orally active antioxidant with reported remyelinating properties.
- Shown to inhibit NF-κB signaling pathways.
- High listed purity (approximately 99.1%).
- Available as solid (10 mg-500 mg) and 10 mM DMSO solution formats for experimental flexibility.
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Medchemexpress LLC JAK-IN-5 hydrochloride | 2751323-21-2 | 99.5% | 511.03 | 50 MG
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JAK-IN-5 hydrochloride is an inhibitor of JAK, extracted from patent US20170121327A1. It is intended for research use only.
- Inhibits JAK.
- Inhibits STAT6 phosphorylation by 60% in IL-13-induced lung tissue in a mouse model of pSTAT6 induction at 0.5 mg/mL (oral aspirate, 50 μL).
- Inhibits 88% of BALF eosinophils in a male C57 mice model of Alternaria alternata-induced eosinophilic inflammation of the lung at 0.1-1.0 mg/mL (oral aspirate, 50 μL).
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Medchemexpress LLC Arecaidine hydrochloride | 6018-28-6 | 5 MG
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Arecaidine hydrochloride is a pyridine alkaloid that acts as a potent GABA uptake inhibitor. It is also identified as a substrate of H+-coupled amino acid transporter 1 (PAT1, SLC36A1) and has been shown to competitively inhibit L-proline uptake.
- Acts as a potent GABA uptake inhibitor
- Functions as a substrate of H+-coupled amino acid transporter 1 (PAT1, SLC36A1)
- Competitively inhibits L-proline uptake
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Medchemexpress LLC CP-466722 | 1080622-86-1 | 99.7% | 349.35 | 1 ML
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CP-466722 is a rapidly reversible inhibitor of ATM (IC50 of 0.41 μM). It does not affect PI3K or related PIKK family members. This compound is for research use only. It effectively inhibits IR-induced ATM kinase activity, with this inhibition being rapid and completely reversible.
- Inhibits p53 induction and ATM-dependent phosphorylation in mouse cells.
- Does not inhibit ATR activity.
- Disrupts ATM-dependent cell cycle checkpoints.
- Completely inhibits ATM-dependent phosphorylation in MCF7 cells at 1 μM.
- Reduces pKAP1 phosphorylation in MCF7 cells (IC50 of 0.41 μM at 10 μM).
- Inhibits both pATM and pKAP1 signals.
- Inhibits proliferation of SKBr-3 cancer cells more strongly than MCF-7.
- Slightly increases proportions of MCF-7 and SKBr-3 cells in G1 phase after 48 hours.
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Medchemexpress LLC HY-12751A 100mg Medchemexpress, Trimethobenzamide hydrochloride CAS:554-92-7 Purity:>98%
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Medchemexpress, HY-12751A 100mg Trimethobenzamide hydrochloride CAS:554-92-7 Trimethobenzamide hydrochloride is a blocker of the D2 receptor. Trimethobenzamide is an antiemetic used to prevent nausea and vomiting. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-124960 5mg Medchemexpress, CTPB CAS:586976-24-1 Purity:>98%
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Medchemexpress, HY-124960 5mg CTPB CAS:586976-24-1 CTPB is a good activator of p300 histone acetyl transferase (HAT) enzyme. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Chem Service Inc Propoxur | 114-26-1 | MFCD00055455 | 250mg
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This item has a minimum order quantity of 2 per supplier requirements
Propoxur | MW: 209.25 | 114-26-1 | MFCD00055455 | 250mg
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Medchemexpress LLC Galanthamine N-Oxide | 134332-50-6 | 1 MG
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Galanthamine N-Oxide is an alkaloid derived from the bulbs of *Zephyranthes concolor*. This compound acts as an inhibitor of electric eel acetylcholinesterase (AChE) and is recognized for its role in inhibiting substrate accommodation within the active site of *Torpedo californica* AChE (TcAChE), human AChE (hAChE), and human BChE (hBChE) enzymes. It is intended for research use only.
- Derived from *Zephyranthes concolor* bulbs
- Inhibits electric eel acetylcholinesterase (AChE)
- Prominent inhibitor of substrate accommodation in AChE and BChE enzymes
- Target: Cholinesterase (ChE)
- Pathway: Neuronal Signaling
- Appears as a white to off-white solid
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Medchemexpress LLC HY-18957 5mg Medchemexpress, Lifirafenib CAS:1446090-79-4 Purity:>98%
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Medchemexpress, HY-18957 5mg Lifirafenib CAS:1446090-79-4 Lifirafenib (BGB-283) is a novel and potent Raf Kinase and EGFR inhibitor with IC50 values of 23 and 29 nM for recombinant BRafV600E and EGFR, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Zingiberen Newsaponin | 91653-50-8 | 5 MG
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Zingiberen Newsaponin | 91653-50-8 | 5 MG
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eMolecules 4-Benzyloxybenzonitrile | 52805-36-4 | MFCD00079701 | 1g
Oakwood Chemical | 4-Benzyloxybenzonitrile | 1g | 537711442 | 107400 | | 52805-36-4 | MFCD00079701 | 209.248 | C14H11NO
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eMolecules UNC0646 | 1320288-17-2 | MFCD22378486 | 25mg
Ambeed | UNC0646 | 25mg | 528573019 | A880677 | | 1320288-17-2 | MFCD22378486 | 621.915 | C36H59N7O2
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Medchemexpress LLC Iccb-19 Hydrochloride 50Mg | HY-138779-50MG
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Iccb-19 Hydrochloride 50Mg
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