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Filtered Search Results
Medchemexpress LLC Rg-12525 | 120128-20-3 | 98.3% | 423.47 g/mol | C25H21N5O2 | 50 MG
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RG-12525 (NID 525) is a small-molecule research compound that antagonizes peptidoleukotriene receptors (LTC4, LTD4, LTE4), exhibits PPAR-γ agonist activity, and inhibits cytochrome P450 enzymes. It is provided in high-purity solid form and as a DMSO solution for biochemical and pharmacological research, supporting both in vitro and in vivo investigations.
- Potent leukotriene receptor antagonist with low-nanomolar activity.
- Shows PPAR-γ agonist activity (≈60 nM).
- Inhibits CYP3A4 (Ki ≈0.5 μM), useful for metabolism studies.
- Available as solid and DMSO solution for flexible dosing.
- High purity suitable for biochemical and pharmacological assays.
- Applicable to in vitro and in vivo pharmacology research.
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Medchemexpress LLC HY-100131 100mg Medchemexpress, GSK'481 GSK481 CAS:1622849-58-4 Purity:98%
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Medchemexpress,HY-100131 100mg GSK'481 GSK481 CAS:1622849-58-4 Formula:C21H19N3O4 Purity:98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-100639 5mg Medchemexpress, Roflumilast N-oxide CAS:292135-78-5 Purity:>98%
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Medchemexpress, HY-100639 5mg Roflumilast N-oxide CAS:292135-78-5 Roflumilast N-oxide is a PDE type 4 inhibitor. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-116790A 10mg Medchemexpress, (+)-Penbutolol CAS:38363-41-6 Purity:>98%
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Medchemexpress, HY-116790A 10mg (+)-Penbutolol CAS:38363-41-6 (+)-Penbutolol is a β-adrenoceptor antagonist, with an IC50 of 0.74 μM. (+)-Penbutolol is an optical isomer of l-penbutolol with Na+ channel-blocking action. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Selleck Chemical LLC Amuvatinib (MP-470) S1244-2mg
Amuvatinib (MP-470 HPK 56) is a potent and multi-targeted inhibitor of c-Kit PDGFR and Flt3 with IC50 of 10 nM 40 nM and 81 nM respectively Amuvatinib suppresses c-MET and c-RET Amuvatinib is also active as a DNA repair protein Rad51 inhibitor with antineoplastic activity Phase 2
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eMolecules 621-87-4 | Phenoxyacetone | ChemScene | MFCD00008767 | 150.177 | C9H10O2 | 98.000 | CC(=O)COc1ccccc1 | 10g | 686116656
Phenoxyacetone | ChemScene | 621-87-4 | MFCD00008767 | 150.177 | C9H10O2 | 98.000 | CC(=O)COc1ccccc1 | 10g | 686116656
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Medchemexpress LLC 1,1,1,3,3,3-hexafluoropropan-2-yl 4-(3-phenoxybenzyl)piperazine-1-carboxylate | 1416133-89-5 | MFCD22987956 | 99.9% | 462.39 g·mol⁻¹ | C21H20F6N2O3 | 100MG
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JW 642 is a potent inhibitor of monoacylglycerol lipase (MAGL) provided as a research-grade analytical standard for in vitro and analytical applications. It is intended for laboratory research use only and not for human or clinical use. Recommended handling includes storage under inert atmosphere and preparation in anhydrous solvent to maintain stability.
- Potent MAGL inhibitor with low-nanomolar activity.
- High purity: 99.9%.
- Molecular weight: 462.39 g·mol⁻¹.
- Chemical formula: C21H20F6N2O3.
- Supplied as a 100 mg research standard.
- Soluble in DMSO at ≥ 100 mg/mL; hygroscopic DMSO may affect solubility.
- Store solid under nitrogen at 4°C; in solvent store at -80°C (6 months) or -20°C (1 month).
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Medchemexpress LLC N-(3-chloro-4-(6-methoxypyrazolo[1,5-a]pyridine-3-carboxamido)phenyl)-1-(1-(3-cyano-3-methylbutanoyl | 2380027-49-4 | MFCD32263443 | 98.6% | 671.12 | C34H32ClFN8O4 | 5 MG
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CSK-IN-1 is a research-grade small-molecule inhibitor of CSK/Src family tyrosine kinases supplied as a white powder for laboratory use. It corresponds to CAS 2380027-49-4, has molecular formula C34H32ClFN8O4 and molecular weight 671.12 Da. Typical pack sizes include 1 mg, 5 mg, and 10 mg. Storage and purity are batch-dependent and follow standard research-reagent handling recommendations.
- Inhibits Src and related protein tyrosine kinases.
- Supplied as a stable white powder for research use.
- Molecular weight 671.12 Da and formula C34H32ClFN8O4.
- Available in small lab-scale pack sizes (1 mg, 5 mg, 10 mg).
- Recommended storage: powder at -20°C; in solvent at -80°C.
- Batch-specific purity approximately 98.6%.
- Suitable for in vitro biochemical and cellular assays.
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Medchemexpress LLC HY-70074 5mg Medchemexpress, CCG-63802 CAS:620112-78-9 Purity:>98%
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Medchemexpress, HY-70074 5mg CCG-63802 CAS:620112-78-9 CCG-63802 is a selective, reversible and allosteric RGS4 inhibitor. CCG-63802 specifically binds to RGS4 and blocks the RGS4-Gαo interaction, with an IC50 value of 1.9 μM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Hmr-1556 | 223749-46-0 | MFCD12756323 | 100.0% | 411.44 g·mol-1 | C17H24F3NO5S | 25 MG
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HMR 1556 is a chromanol-derived small molecule that selectively blocks the slow delayed rectifier potassium current (IKs) and is used as an experimental tool in cardiac electrophysiology studies. It is supplied as a high-purity research compound for in vitro ion-channel pharmacology applications.
- Potent IKs blockade with low-nanomolar IC50 values (10.5 nM in canine, 34 nM in guinea pig).
- High selectivity for IKs over other cardiac currents.
- Provided as a high-purity research-grade solid suitable for in vitro studies.
- Useful for cardiac electrophysiology and ion-channel pharmacology research.
- Available in multiple small pack sizes for research use.
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Medchemexpress LLC FR194738 FR BS10MM 1ML SOLN
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MedChemExpress | FR194738 free base | 10 mM * 1 mL in DMSO Solution | HY-100303 10 mM * 1 mL in DMSO | Purity: 99.79% | 204067-45-8 | MW: 439.65
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Medchemexpress LLC HY-50709 50mg , A939572 stearoyl-CoA desaturase (SCD) inhibitor;SCD-inhibitor CAS:1032229-33-6 Purity:98%
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Medchemexpress, HY-50709 50mg A939572 stearoyl-CoA desaturase (SCD) inhibitor;SCD-inhibitor CAS:1032229-33-6 Formula:C20H22ClN3O3 IC50: <4 nM (mSCD1), 37 nM (hSCD1) Purity:98% A939572 is a potent, and orally bioavailable SCD1 inhibitor with IC 50 values of <4 nM and 37 nM for mSCD1 and hSCD1 , respectively. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-13998 100mg Medchemexpress, ABT-333 Dasabuvir CAS:1132935-63-7 Purity:98%
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Medchemexpress,HY-13998 100mg ABT-333 Dasabuvir CAS:1132935-63-7 Formula:C26H27N3O5S ABT-333 is a nonnucleoside inhibitor of the RNA-dependent RNA polymerase encoded by the HCV NS5B gene, inhibits recombinant NS5B polymerases derived from HCV genotype 1a and 1b clinical isolates, with IC50 between 2.2 and 10.7 nM. Purity:98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Tivozanib hydrochloride hydrate | 682745-41-1 | 99.8% | 509.34 | 10 MG
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Tivozanib hydrochloride hydrate is the hydrate hydrochloride form of Tivozanib. It is a selective, orally active inhibitor for vascular endothelial growth factor receptor (VEGFR)-1, 2, and 3, with IC50s of 30, 6.5, and 15 nM, respectively. It exhibits antitumor efficacy.
- Selective, orally active inhibitor for VEGFR-1, 2, and 3.
- Exhibits antitumor efficacy.
- Inhibits the phosphorylation of VEGFR-1, VEGFR-2, and VEGFR-3.
- Inhibits VEGF-induced proliferation and migration of HUVECs.
- Selectively inhibits VEGF-stimulated phosphorylation of MAPKs in endothelial cells.
- Exhibits antitumor efficacy against various cancers in athymic mice models.
- Reversibly suppresses vascular permeability and angiogenesis.
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Medchemexpress LLC HY-13992 1mg Medchemexpress, AP20187 CAS:195514-80-8 Purity:>98%
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Medchemexpress, HY-13992 1mg AP20187 CAS:195514-80-8 AP20187 (B/B Homodimerizer) is a cell-permeable ligand used to dimerize FK506-binding protein (FKBP) fusion proteins and initiate biological signaling cascades and gene expression or disrupt protein-protein interactions. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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