Phenoxy compounds
Enzo Life Sciences URB-602 (50mg). CAS: 565460-15-3
Selectively inhibits monoacylglycerol (MAG) lipase (IC50=28µM) via a noncompetitive mechanism. Does not inhibit FAAH, DAG lipase or COX-2. URB-602 selectively raises levels of 2-arachidonoylglycerol with no change in anandamide concentrationsin cells and tissues. In the same way anandamide levels were markely elevated by the FAAH inhibitor URB597 at 1µM. Alternative name: Biphenyl-3-yl carbamic acid cyclohexyl ester. Purity: ≥98% (TLC). Solubility: Soluble in DMSO (30 mg/ml) or ethanol (5 mg/ml warm). Long Term Storage: Ambient.
Medchemexpress LLC HY-100544 5mg Medchemexpress, FLLL32 CAS:1226895-15-3 Purity:>98%
Medchemexpress, HY-100544 5mg FLLL32 CAS:1226895-15-3 FLLL32, a synthetic analog of curcumina, is a JAK2/STAT3 dual inhibitor with anti-tumor activity [1] [2] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-100544 100mg Medchemexpress, FLLL32 CAS:1226895-15-3 Purity:>98%
Medchemexpress, HY-100544 100mg FLLL32 CAS:1226895-15-3 FLLL32, a synthetic analog of curcumina, is a JAK2/STAT3 dual inhibitor with anti-tumor activity [1] [2] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
eMolecules 5-(4-Chlorophenyl)-4-(4-ethoxybenzoyl)-1,5-dihydro-3-hydroxy-1-(2-thiazolyl)-2H-pyrrol-2-one | 380584-15-6 | MFCD02989816 | 10mg
Oakwood Chemicals | 5-(4-Chlorophenyl)-4-(4-ethoxybenzoyl)-1,5-dihydro-3-hydroxy-1-(2-thiazolyl)-2H-pyrrol-2-one | 10mg | 480151905 | 101694 | | 380584-15-6 | MFCD02989816 | 440.900 | C22H17ClN2O4S
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool
Medchemexpress LLC 1-cyclobutyl-3-(2,6-dimethylphenyl)-3,4-dihydro-pyrimido[4,5-d]pyrimidin-2(1H)-one (methoxy-piperazinyl substituted) | 2172617-15-9 | 99.8% | 5 MG
YKL-06-061 is a potent, selective, second-generation salt-inducible kinase (SIK) inhibitor for research use. It inhibits SIK1, SIK2, and SIK3 with IC50 values of 6.56 nM, 1.77 nM, and 20.5 nM, respectively. The compound is supplied as a high-purity solid with good DMSO solubility for biochemical and cellular studies.
- Potent inhibition of SIK1, SIK2, and SIK3 at low-nanomolar concentrations.
- High purity suitable for research applications.
- Soluble in DMSO at 16.67 mg/mL (31.59 mM).
- Solid storage recommended at -20°C; in solution store at -80°C for long-term stability.
- Available in small research sizes for assay development.
Medchemexpress LLC Tivozanib hydrochloride hydrate | 682745-41-1 | 99.8% | 509.34 | 10 MG
Tivozanib hydrochloride hydrate is the hydrate hydrochloride form of Tivozanib. It is a selective, orally active inhibitor for vascular endothelial growth factor receptor (VEGFR)-1, 2, and 3, with IC50s of 30, 6.5, and 15 nM, respectively. It exhibits antitumor efficacy.
- Selective, orally active inhibitor for VEGFR-1, 2, and 3.
- Exhibits antitumor efficacy.
- Inhibits the phosphorylation of VEGFR-1, VEGFR-2, and VEGFR-3.
- Inhibits VEGF-induced proliferation and migration of HUVECs.
- Selectively inhibits VEGF-stimulated phosphorylation of MAPKs in endothelial cells.
- Exhibits antitumor efficacy against various cancers in athymic mice models.
- Reversibly suppresses vascular permeability and angiogenesis.
Medchemexpress LLC HY-120012 10mg Medchemexpress, AZD9567 CAS:1893415-00-3 Purity:>98%
Medchemexpress, HY-120012 10mg AZD9567 CAS:1893415-00-3 AZD9567 (compound 15) is a potent, oral active, non-steroidal and selective glucocorticoid receptor modulator (SGRM), with an IC50 of 3.8 nM. Exhibits excellent efficacy in the streptococcal cell wall (SCW) reactivation model of joint inflammation. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-120056 10mg Medchemexpress, YKL-06-061 CAS:2172617-15-9 Purity:>98%
Medchemexpress, HY-120056 10mg YKL-06-061 CAS:2172617-15-9 YKL-06-061 is a potent, selective, second-generation salt-inducible kinase (SIK) inhibitor with IC50 values of 6.56 nM/1.77 nM/20.5 nM for SIK1/2/3, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC PXS-5153A (monohydrochloride) | 2125956-82-1 | 99.6% | 438.95 | 50 MG
PXS-5153A monohydrochloride is a potent, selective, orally active and fast-acting lysyl oxidase like 2/3 enzymatic (LOXL2/LOXL3) inhibitor, with an IC50 of <40 nM for LOXL2 across all mammalian species and an IC50 of 63 nM for human LOXL3. PXS-5153A monohydrochloride could reduce crosslinks and ameliorate fibrosis.
- Exhibits an IC50 of <40 nM for LOXL2 across all mammalian species tested.
- Also inhibits human LOXL3 with an IC50 value of 63 nM.
- Is >40-fold selective for LOXL2 over both LOX and LOXL1 and >700-fold selective over other related amine oxidases.
- Is a fast acting inhibitor, with enzymatic activity almost entirely blocked within 15 minutes.
- Reduces crosslinks and ameliorates fibrosis.
Medchemexpress LLC PXS-5153A monohydrochloride | 2125956-82-1 | 99.59% | 438.95 | 100 MG
PXS-5153A monohydrochloride is a potent, selective, orally active, and fast-acting lysyl oxidase like 2/3 enzymatic (LOXL2/LOXL3) inhibitor. It has an IC50 of <40 nM for LOXL2 across all mammalian species and an IC50 of 63 nM for human LOXL3. This compound can reduce crosslinks and ameliorate fibrosis.
- Potent, selective, orally active, and fast-acting LOXL2/LOXL3 inhibitor.
- IC50 of <40 nM for LOXL2 across all mammalian species.
- IC50 of 63 nM for human LOXL3.
- >40-fold selective for LOXL2 over LOX and LOXL1.
- >700-fold selective over other related amine oxidases.
- Fast-acting, with enzymatic activity almost entirely blocked within 15 minutes.
- Reduces crosslinks and ameliorates fibrosis.
Medchemexpress LLC HY-18874 1mg Medchemexpress, p38-α MAPK-IN-1 CAS:443913-15-3 Purity:>98%
Medchemexpress, HY-18874 1mg p38-α MAPK-IN-1 CAS:443913-15-3 p38-α MAPK-IN-1 is an inhibitor of MAPK14 (p38-α), with IC50 of 2300 nM in EFC displacement assay, and 5500 nM in HTRF assay. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.