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Organic compounds that consist of a phenylcarbamic acid where the hydrogen atom bonded to the oxygen atom is replaced with an organic group; phenylcarbamic acid a carboxylic acid bonded to an amino group with a phenyl group substitution.
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(4S)-1-Boc-4-fluoro-D-proline is an N-Boc protected, 4-fluoro substituted D-proline derivative used as a synthetic building block in medicinal chemistry and peptide synthesis. It is employed as an amino acid scaffold for preparing peptidomimetics, modified peptides, and small-molecule intermediates.
N-Boc protected 4-fluoro D-proline scaffold for synthesis.
Suitable for peptide synthesis and peptidomimetic preparation.
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(4S)-1-Boc-4-fluoro-D-proline is a Boc-protected, fluorinated D-proline derivative used as a building block in organic synthesis and peptide chemistry. It serves as an intermediate for preparing peptidomimetics and other fluorinated analogs where stereochemistry and fluorine incorporation are important.
Boc-protected fluorinated D-proline for synthetic versatility.
High reported purity suitable for research applications.
Defined stereochemistry (4S) for stereospecific synthesis.
Useful in peptide and peptidomimetic construction.
Available in small-scale sizes appropriate for lab use.
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Bromo-PEG2-C2-Boc is a PEG-based PROTAC linker, catalog number HY-141365, designed for the synthesis of PROTACs. PROTACs utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins by connecting an E3 ubiquitin ligase ligand and a target protein ligand via a linker like this product. It is intended for research use only.
Purity: 97.0%
Molecular weight: 297.19
Appearance: Liquid
Color: Colorless to light yellow
Solubility: Soluble in DMSO (100 mg/mL)
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Acid-C1-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein, enabling the selective degradation of target proteins through the intracellular ubiquitin-proteasome system.
PEG-based PROTAC linker
Used in the synthesis of PROTACs
Enables selective degradation of target proteins
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Boc-NH-PEG7-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. These molecules contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
peg-based protac linker for synthesis of protacs
facilitates the degradation of target proteins
utilizes the intracellular ubiquitin-proteasome system
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(±)-Boc-α-phosphonoglycine trimethyl ester functions as a glycine equivalent and donor in organic synthesis. Its reaction byproducts are water-soluble and easily purified. It facilitates the efficient synthesis of 5,6- and 5,8-dimethoxy-substituted ester products via four mild reactions.
Serves as a glycine equivalent and glycine donor
Possesses strong α-proton acidity
Reaction byproducts are water-soluble and easy to purify
Used to efficiently obtain 5,6- and 5,8-dimethoxy-substituted ester products
Achieved through four mild reactions
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Bromo-PEG1-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
PEG-based PROTAC linker.
Used in the synthesis of PROTACs.
Exploits the intracellular ubiquitin-proteasome system for selective protein degradation.
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(4S)-1-Boc-4-fluoro-D-proline is a Boc-protected, fluoro-substituted D-proline derivative used as a synthetic building block in organic and medicinal chemistry. It supplies a stereodefined fluorinated proline residue for incorporation into peptides and small molecules, enabling conformation control and exploration of structure-activity relationships.
Boc-protected amino acid compatible with standard peptide coupling chemistry.
Fluorine substitution at the 4-position to influence conformational preference and metabolic stability.
D-configuration (4S) provides stereochemical control for peptide design.
High chemical purity suitable for synthesis applications.
Available in gram-scale quantities for preparative synthesis.
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(4S)-1-Boc-4-fluoro-D-proline is a Boc-protected, fluorinated D-proline derivative used as a building block in peptide and small-molecule synthesis. Provided as a solid powder, it enables incorporation of a 4-fluoro D-proline residue to modulate conformation and physicochemical properties during medicinal chemistry and peptide design.
Boc-protected amino acid enabling selective coupling in synthesis.
Contains a 4-fluoro D-proline residue for altered sterics and polarity.
High purity (97.0%) suitable for research synthesis.
Molecular weight 233.24 g/mol; formula C10H16FNO4.
Supplied as a solid, white to off-white, available in gram-scale quantities.
Stable under recommended storage conditions for long-term use.
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(R)-1-Boc-3-methyl-piperazine is a chemical intermediate that can be used for the preparation of Compound I3, which exhibits anticancer activity against colorectal adenocarcinoma with BRCA2 gene deletion. For research use only. We do not sell to patients.
Can be used to prepare Compound I3, which exhibits anticancer activity against colorectal adenocarcinoma with BRCA2 gene deletion.
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Acid-PEG5-C2-Boc is a chemical compound with the molecular formula C18H34O9 and a molecular weight of 394.46. It is supplied in liquid form, ranging from colorless to light yellow. This product has a purity of ≥98.0% as determined by NMR spectroscopy, and its 1H NMR spectrum is consistent with its structure.
Colorless to light yellow liquid appearance
High purity of ≥98.0% by NMR
1H NMR spectrum consistent with structure
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4-(4-Boc-piperazinemethyl)phenylboronic acid pinacol ester is a PROTAC linker that can be utilized in the synthesis of CST905. PROTACs consist of two distinct ligands connected by a linker, one targeting an E3 ubiquitin ligase and the other targeting the protein of interest. These compounds leverage the intracellular ubiquitin-proteasome system to facilitate the selective degradation of target proteins.
Functions as a PROTAC linker
Can be used in the synthesis of certain PROTAC compounds
Designed to target E3 ubiquitin ligases and specific proteins of interest
Utilizes the ubiquitin-proteasome system for targeted protein degradation
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N-(4-aminophenyl)-N-methyl-2-(4-methylpiperazin-1-yl)acetamide is a chemical compound that acts as a reagent for the preparation of deuterated derivatives of nintedanib. It is used in studies related to angiokinase inhibitory, antitumor activity, and pharmacokinetic properties.
Reagent for preparation of deuterated derivatives of nintedanib
Useful in angiokinase inhibitory research
Applied in antitumor activity studies
Valuable for pharmacokinetic property investigations
Solid form
Off-white to pale beige color
Melting point of 152-154°C
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Also available in 1 mL, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 200 mg and bulk. Please contact Fisher for quotes.N-Desmethyl-Apalutamide is a less potent antagonist of the androgen receptor, is an active Apalutamide metabolite. Purity 97.83%
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