Phenylhydrazines
Medchemexpress LLC Tetracycline hydrochloride | 64-75-5 | 98.7% | 50 G
Tetracycline hydrochloride is a broad-spectrum antibiotic with oral activity, effective against a wide range of bacteria including gram-positive and gram-negative bacteria, chlamydiae, mycoplasmas, and rickettsiae. This compound is intended for research on infections and can be utilized in animal modeling to create genetically engineered disease models. It has demonstrated activity in inhibiting L-amyloid aggregates and disassembling pre-formed fibrils.
- Effective against a wide range of bacteria
- Suitable for research related to infections
- Utilized in animal modeling for genetically engineered disease models
- Inhibits L-amyloid aggregates and disassembles pre-formed fibrils
- Shows susceptibility against Vibrio vulnificus strain B3547
- Induces tumor regression in mice
Medchemexpress LLC Clomipramine hydrochloride | 17321-77-6 | 99.6% | 100 MG
Clomipramine hydrochloride is a potent 5-HT reuptake blocker with an IC50 value of 1.5 nM. It is a tricyclic antidepressant primarily used for research into depression and obsessive compulsive disorder (OCD). This compound also inhibits the reuptake of both noradrenaline and 5-HT, with a stronger inhibition of 5-HT reuptake.
- Potent 5-HT reuptake blocker
- Tricyclic antidepressant
- Supports research on depression and obsessive compulsive disorder (OCD)
- Inhibits both noradrenaline and 5-HT reuptake
- Interferes with autophagic flux
Medchemexpress LLC Clomipramine (hydrochloride) | 17321-77-6 | 99.6% | 1 ML
Clomipramine hydrochloride is a potent 5-HT reuptake blocker with an IC50 value of 1.5 nM. This tricyclic antidepressant is used in research for depression and obsessive compulsive disorder (OCD).
- Potent 5-HT reuptake blocker.
- Tricyclic antidepressant for depression and OCD research.
- Inhibits reuptake of both noradrenaline and 5-HT.
- Interferes with autophagic flux and compromises tumorigenic cell viability.
- Reduces autophagy in neuronal primary cultures.
- Elicits hyperglycemia in mice by blocking 5-HT2B and/or 5-HT2C receptors.
- Reduces immobility in the forced swimming test in mice.
- Inhibits marble burying behavior in mice.
Medchemexpress LLC Levofloxacin hydrochloride | 177325-13-2 | 99.0% | 1 G
Levofloxacin hydrochloride is an orally active antibiotic that inhibits DNA gyrase and topoisomerase IV activity, inducing apoptosis. It possesses broad-spectrum antibacterial activity and exhibits anticancer properties. It is widely used in research for infectious diseases and lung cancer.
- Inhibits DNA gyrase and topoisomerase IV activity
- Active against Gram-positive and Gram-negative bacteria
- Exhibits anticancer activity against lung cancer cells
- Provides anti-acnegenic, anxiogenic, and analgesic effects
- Shortens sleep duration in mice
- Used in research for tuberculosis, chronic periodontitis, bacterial infections, and BK viremia
Medchemexpress LLC AG-636 | 1623416-31-8 | 98.07% | 343.38 | 25 MG
AG-636 is a potent, reversible, selective, and orally active dihydroorotate dehydrogenase (DHODH) inhibitor. It demonstrates strong anticancer effects by inhibiting DHODH with an IC50 of 17 nM.
- Potent, reversible, selective, and orally active DHODH inhibitor
- Inhibits dihydroorotate dehydrogenase (DHODH) with an IC50 of 17 nM
- Exhibits strong growth-inhibitory activity in cancer cell lines
- Demonstrates robust tumor growth inhibition in xenograft lymphoma tumor models
Medchemexpress LLC Pipendoxifene hydrochloride | 245124-69-0 | 99.83% | 493.04 | 1 ML
Pipendoxifene hydrochloride is a selective estrogen receptor modulator (SERM) developed for breast cancer research. It is a 2-phenyl indole SERM that has demonstrated an excellent preclinical pharmacological profile and has been selected for further development as a treatment for metastatic breast cancer.
- Selective estrogen receptor modulator (SERM).
- Used in research for breast cancer.
- New 2-phenyl indole SERM with excellent preclinical pharmacological profile.
- Available in various forms including solid and solution (e.g., 10 mM in DMSO).
- High purity (99.83%).
eMolecules 1408076-34-5 | 4-methoxyazepane hydrochloride | MFCD21641983 | 1g
Ambeed | Methyl 2-(1H-indol-3-yl)-2-oxoacetate | 25g | 525137099 | A225489 | 18372-22-0 | MFCD00047173 | 203.197 | C11H9NO3
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Medchemexpress LLC Promethazine hydrochloride | 58-33-3 | 99.85% | 5 G
Promethazine hydrochloride is an orally active phenothiazine derivative with antihistaminic (H1), sedative, antiemetic, anticholinergic, and antimotion sickness properties. It is a potent H1 receptor antagonist and a mAChR antagonist, also having affinity for 5-HT2A and 5-HT2C receptors. This compound is for research use only.
- Potent H1 receptor antagonist
- mAChR antagonist
- Affinity for 5-HT2A and 5-HT2C receptors
- Orally active phenothiazine derivative
- Exhibits sedative, antiemetic, anticholinergic, and antimotion sickness properties
Medchemexpress LLC Leriglitazone hydrochloride | 146062-46-6 | MFCD00055081 | 99.6% | 408.90 | C19H21ClN2O4S | 1 ML
Leriglitazone hydrochloride is the hydrochloride salt of leriglitazone (MIN-102), a brain-penetrant PPARγ agonist used in preclinical research on neuroinflammation, mitochondrial function, and neurodegeneration. Supplied for research use as a 10 mM solution in DMSO (1 mL) and as solid quantities for custom preparation.
- Ready-to-use 10 mM solution in DMSO (1 mL) for cell-based or biochemical assays.
- High purity (≈99.6%) suitable for research applications.
- Also available as solid material for custom dilution and dosing.
- Useful for studies of PPARγ-mediated neuroprotection and mitochondrial regulation.
- Provided with supporting datasheet and SDS for handling and safety.
Medchemexpress LLC Triprolidine (hydrochloride monohydrate) | 6138-79-0 | 99.9% | 1 ML
Triprolidine hydrochloride monohydrate is a first-generation antihistamine that acts as an oral active histamine H1 antagonist. It can be utilized in research concerning allergic rhinitis and has demonstrated spinal motor and sensory block in rats.
- First-generation antihistamine.
- Oral active histamine H1 antagonist.
- Applicable for allergic rhinitis research.
- Exhibits spinal motor and sensory block in rats.
Medchemexpress LLC CDK4/6-IN-15 (hydrochloride) | 2078047-99-9 | MFCD09904297 | 99.3% | C21H28ClFN8S | 100 MG
CDK4/6-IN-15 (hydrochloride) is an orally active and selective CDK4/6 inhibitor that potently inhibits cancer cell growth. It arrests the cell cycle at the G1 phase and suppresses retinoblastoma tumour suppressor protein (Rb) phosphorylation at S780 and E2 factor (E2F)-regulated gene expression.
- Potently inhibits cancer cell growth
- Arrests the cell cycle at G1 phase
- Suppresses retinoblastoma tumour suppressor protein (Rb) phosphorylation at S780
- Suppresses E2 factor (E2F)-regulated gene expression
Medchemexpress LLC 1-(3-fluorophenyl)-2-((2-((2,3,4-trifluorophenyl)methoxy)phenyl)methyl)pyrrolidine hydrochloride | 1227056-87-2 | 99.5% | 357.80 g/mol | C18H19ClF3NO | 5 MG
Ampreloxetine hydrochloride is an orally active, CNS-penetrant inhibitor of the norepinephrine transporter (NET) and the serotonin uptake transporter (SERT) supplied for research use. It is used in vitro and in vivo to investigate monoamine transporter pharmacology and CNS transporter-related mechanisms.
- Orally active inhibitor of norepinephrine and serotonin transporters.
- CNS-penetrant, suitable for in vivo and in vitro studies.
- Hydrochloride salt form for improved handling and solubility.
- High reported purity (99.5%).
- Supplied in milligram quantities for research applications.
- Useful for pharmacology, transporter mechanism, and CNS studies.
Medchemexpress LLC (+)-Niguldipine hydrochloride | 113145-69-0 | MFCD00873564 | 98.1% | 646.17 g/mol | C36H40ClN3O6 | 5 MG
(+)-Niguldipine hydrochloride is the S-enantiomer of niguldipine, a dihydropyridine calcium-channel blocker and α1-adrenergic receptor antagonist used in pharmacological and cardiovascular research. The compound is supplied as a high-purity solid for in vitro and biochemical studies. Certificate of Analysis, data sheet, and SDS are available; handle and store sealed, away from moisture, following the supplier COA.
Medchemexpress LLC M-PEG3-0-benzaldehyde | 153364-63-7 | C14H20O5 | 500 MG
M-PEG3-0-benzaldehyde is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs consist of two ligands connected by a linker, one binding to an E3 ubiquitin ligase and the other targeting a specific protein. These molecules utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins. This product is for research use only.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Leverages the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC Idalopirdine hydrochloride | 467458-02-2 | 99.6% | C20H20ClF5N2O | 25 MG
Idalopirdine hydrochloride (Lu AE58054 hydrochloride) is a potent, selective 5-HT6 receptor antagonist with a Ki value of 0.83 nM. It is intended for research and analytical applications and may be used in studies of Alzheimer's disease and schizophrenia, among other related disorders. This product has been tested and complies with given specifications, but has not been fully validated for medical applications.
- Potent, selective 5-HT6 receptor antagonist
- Ki value of 0.83 nM
- May be used in studies of Alzheimer's disease
- May be used in studies of schizophrenia
- Intended for research and analytical applications